Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Jeremy Pratt"'
Autor:
Natasha K, Brusco, Annette, Alafaci, Jane, Tuckerman, Helena, Frawley, Jeremy, Pratt, Andrew J, Daley, Angela K, Todd, Yi-Mo, Deng, Kanta, Subbarao, Ian, Barr, Nigel W, Crawford
Publikováno v:
Communicable Diseases Intelligence. 46
Respiratory syncytial virus (RSV) is one of the principal causes of acute bronchiolitis and respiratory tract infections in young children. Routine RSV surveillance in Australian children is limited; vaccines are in late stage development; prophylact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2543f75ca8a9cef8416b124710e35122
https://doi.org/10.33321/cdi.2022.46.5
https://doi.org/10.33321/cdi.2022.46.5
Autor:
Hans-Paul Juretschke, Ralf Elvert, Werner Kramer, Michaela Liebig, Guido Haschke, Andreas W. Herling, Claudia Neumann-Haefelin, Mark D. Black, Matthias Gossel, Jeremy Pratt
Publikováno v:
Obesity. 18:1952-1958
This is the first study to examine the effect of subchronic olanzapine (OLZ) on energy homeostasis in rats, covering all aspects of energy balance, including energy intake as metabolizable energy, storage, and expenditure. We further analyzed whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9754d1c393c044ce1d4220be6a62e0c
https://doi.org/10.1038/oby.2010.17
https://doi.org/10.1038/oby.2010.17
Autor:
Veronique Mary, Odile Grosjean-Piot, Jean-Marie Stutzmann, Jeremy Pratt, Florence Wahl, Andre Uzan
Publikováno v:
CNS Drug Reviews. 8:1-30
The development of treatments for acute neurodegenerative diseases (stroke and brain trauma) has focused on (i) re‐establishing blood flow to ischemic areas as quickly as possible (i.e. mainly antithrombotics or thrombolytics for stroke therapy) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::627fa66ad725f66d28f11c7c32f7b93d
https://doi.org/10.1111/j.1527-3458.2002.tb00213.x
https://doi.org/10.1111/j.1527-3458.2002.tb00213.x
Autor:
Nacer Abbas, Patrice Denefle, Jeremy Pratt, Maria Angeles Mena, Gunter Tremp, Thomas Rooney, Eva Gallego, Marina P. Sánchez, Gwénnäelle Ret, Francisco Araujo, Chantal Joubert, Justo García de Yébenes, Pablo Ibanez, Alexis Brice, Rosa M. Solano, Olga Corti, Charles Cohen-Salmon, Jean Michel Itier, Laurent Pradier, Michel Laville, Magali Periquet, Santiago Canals, Alba Serrano, María José Casarejos, Julia Negroni, Georg Andrees Bohme, Jesus Benavides
Publikováno v:
Human Molecular Genetics. 12:2277-2291
Mutations of the parkin gene are the most frequent cause of early onset autosomal recessive parkinsonism (EO-AR). Here we show that inactivation of the parkin gene in mice results in motor and cognitive deficits, inhibition of amphetamine-induced dop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08af4b7c2aabd7f608f69e18482c3683
https://doi.org/10.1093/hmg/ddg239
https://doi.org/10.1093/hmg/ddg239
Autor:
Jeremy Pratt, Guillaume Birraux, Patrick Jimonet, Alain Boireau, Jean Marie Stutzmann, Serge Mignani, Arielle Genevois-Borella, Dominique Damour, Florence Wahl, Marc Williams Debono, Marc Vuilhorgne, Georg Andrees Bohme
Publikováno v:
Bioorganic & Medicinal Chemistry. 10:1627-1637
Excessive release of glutamate, a potent excitatory neurotransmitter, is thought to play an important role in a variety of acute and chronic neurological disorders, suggesting that excitatory amino acid antagonists may have broad therapeutic potentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15f8ad3bdc58720bd70bc789f47bb6c7
https://doi.org/10.1016/s0968-0896(01)00431-x
https://doi.org/10.1016/s0968-0896(01)00431-x
Autor:
Marc Williams Debono, Patrick Jimonet, Arielle Genevois-Borella, John Randle, Yves Ribeill, Serge Mignani, Alain Boireau, Dominique Damour, Marc Vuilhorgne, Georg Andrees Bohme, Jean-Marie Stutzmann, Jeremy Pratt
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 11:1205-1210
The overstimulation of excitatory amino acid receptors such as the glutamate AMPA receptor has been implicated in the physiopathogenesis of epilepsy as well as in acute and chronic neurodegenerative disorders. An original series of readily water solu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1be2de3f0a9672b1df14d4985d7b501e
https://doi.org/10.1016/s0960-894x(01)00180-9
https://doi.org/10.1016/s0960-894x(01)00180-9
Autor:
Arielle Genevois-Borella, Georg Andrees Bohme, Franco Manfre, Alain Boireau, Yves Ribeill, Marc Williams Debono, Patrick Jimonet, Jean-Marie Stutzmann, Jeremy Pratt, Dominique Damour, Jean Bouquerel, Philippe Hubert, Marc Vuilhorgne, John Randle, Patrick Nemecek, Jean-Claude Hardy, Serge Mignani
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 11:127-132
A novel series of 2- and 9-disubstituted heterocyclic-fused 4-oxo-indeno[1,2- e ]pyrazin derivatives was synthesized. One of them, the 9-(1 H -tetrazol-5-ylmethyl)-4-oxo-5,10-dihydroimidazo[1,2- a ]indeno[1,2- e ]pyrazin-2-yl phosphonic acid 4i exhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4ac0e92b179b6bdf461d575d0a942d3
https://doi.org/10.1016/s0960-894x(00)00592-8
https://doi.org/10.1016/s0960-894x(00)00592-8
Autor:
John Randle, Alain Boireau, Jean-Marie Stutzmann, Patrick Jimonet, Jeremy Pratt, Dominique Damour, Arielle Genevois-Borella, Serge Mignani, Marc Williams Debono, Marc Vuilhorgne, Yves Ribeill, Georg Andrees Bohme
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 10:2749-2754
The over-stimulation of excitatory amino acid receptors such as the glutamate AMPA receptor has been suggested to be associated with neurodegenerative disorders. Here we describe an original series of readily water soluble 4-oxo-imidazo[1,2-a] indeno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10737b7c9953a61e4271b1d429d74468
https://doi.org/10.1016/s0960-894x(00)00561-8
https://doi.org/10.1016/s0960-894x(00)00561-8
Autor:
Jean-Marie Stutzmann, Marc Williams Debono, Alain Boireau, Arielle Genevois-Borella, Michel Cheve, Dominique Damour, Assunta Imperato, John Randle, Yves Ribeill, Jeremy Pratt, Serge Mignani, Patrick Jimonet, Marc Vuilhorgne, Georg Andrees Bohme
Publikováno v:
Bioorganic & Medicinal Chemistry. 8:2211-2217
Water soluble 8-methylureido-10-amino-10-methyl-imidazo[1,2-a]indeno[1,2-e]pyraz ine-4-one 4 represents a novel class of highly potent and selective AMPA receptors antagonists with in vivo activity. The dextrorotatory isomer (+)-4 was found to displa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::675b2882dda673cbc94a2c3686682c41
https://doi.org/10.1016/s0968-0896(00)00161-9
https://doi.org/10.1016/s0968-0896(00)00161-9
Autor:
Jeremy Pratt, Arielle Genevois-Borella, Michel Cheve, Georg Andrees Bohme, Yves Ribeill, Franco Manfre, Patrick Jimonet, Jean Marie Stutzmann, Alain Boireau, S. Le Guern, A. Doble, John Randle, Serge Mignani, F. Herman, Dominique Damour, Assunta Imperato
Publikováno v:
Journal of Medicinal Chemistry. 43:2371-2381
Indeno[1,2-b]pyrazin-2,3-diones have been identified as a novel series of potent ligands on the glycine site of the NMDA receptor. To improve their in vivo activities, an acetic acid-type side chain was introduced to the 5-position, giving water-solu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdb6bb95b505689a045ccf42c7891307
https://doi.org/10.1021/jm990957g
https://doi.org/10.1021/jm990957g