Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jeremy Petravicz"'
Autor:
Mriganka Sur, Rodrigo Garófallo Garcia, Jeremy Petravicz, Rajeev V. Rikhye, Nikolaos Mellios, Grayson O. Sipe
Publikováno v:
Glia
The uptake of glutamate by astrocytes actively shapes synaptic transmission, however its role in the development and plasticity of neuronal circuits remains poorly understood. The astrocytic glutamate transporter, GLT1 is the predominant source of gl
Publikováno v:
Society for Neuroscience
Journal of Neuroscience, 38(16), 3890-3900. Society for Neuroscience
Journal of Neuroscience, 38(16), 3890-3900. Society for Neuroscience
Microdeletion of a region in chromosome 16p11.2 increases susceptibility to autism. Although this region contains exons of 29 genes, disrupting only a small segment of the region, which spans five genes, is sufficient to cause autistic traits. One ca
Publikováno v:
Journal of Neuroscience. 34:10256-10263
Accumulating evidence points to a role for Janus kinase/signal transducers and activators of transcription (STAT) immune signaling in neuronal function; however, its role in experience-dependent plasticity is unknown. Here we show that one of its com
Autor:
Jeremy Petravicz, Showming Kwok, Nikolaos Mellios, Jonathan Woodson, Daniela Tropea, Abhishek Banerjee, Jorge Castro, Mriganka Sur, Rodrigo Garófallo Garcia
Publikováno v:
Proceedings of the National Academy of Sciences. 111:9941-9946
Rett Syndrome is a neurodevelopmental disorder that arises from mutations in the X-linked gene methyl-CpG binding protein 2 (MeCP2). MeCP2 has a large number of targets and a wide range of functions, suggesting the hypothesis that functional signalin
Autor:
Elizabeth J. Sweger, Ken D. McCarthy, Todd A. Fiacco, Suzanne K. Minton, Sarah Taves, Kristen B. Casper, Jeremy Petravicz, Cendra Agulhon, Allison B. McMullen
Publikováno v:
Neuron. 59:932-946
Astrocytes comprise approximately half of the volume of the adult mammalian brain and are the primary neuronal structural and trophic supportive elements. Astrocytes are organized into distinct nonoverlapping domains and extend elaborate and dense fi
Publikováno v:
The Journal of Neuroscience. 28:4967-4973
Astrocytes in the hippocampus release calcium (Ca2+) from intracellular stores intrinsically and in response to activation of Gq-linked G-protein-coupled receptors (GPCRs) through the binding of inositol 1,4,5-trisphosphate (IP3) to its receptor (IP3
Autor:
Sarah Taves, Ken D. McCarthy, Todd A. Fiacco, Kristen B. Casper, Xinzhong Dong, Cendra Agulhon, Ju Chen, Jeremy Petravicz
Publikováno v:
Neuron. 54(4):611-626
Astrocytes are considered the third component of the synapse, responding to neurotransmitter release from synaptic terminals and releasing gliotransmitters--including glutamate--in a Ca(2+)-dependent manner to affect neuronal synaptic activity. Many
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 9 (2015)
Frontiers in Cellular Neuroscience
Frontiers Research Foundation
Frontiers in Cellular Neuroscience
Frontiers Research Foundation
Astrocytes are the predominant glial type in the central nervous system and play important roles in assisting neuronal function and network activity. Astrocytes exhibit complex signaling systems that are essential for their normal function and the ho
Publikováno v:
BMC Neuroscience
Several recent studies reveal a close interplay of neurons and astrocytes in information processing [1]. Astrocytes affect neural transmission by their control of glutamate concentrations by glutamate transporters [2] in direct vicinity to the synapt
Autor:
Gertrudis Perea, Naiyan Chen, Mriganka Sur, Jitendra Sharma, Hiroki Sugihara, Jeremy Petravicz, Chuong Le
Publikováno v:
Proceedings of the National Academy of Sciences. 109
Although cholinergic innervation of the cortex by the nucleus basalis (NB) is known to modulate cortical neuronal responses and instruct cortical plasticity, little is known about the underlying cellular mechanisms. Using cell-attached recordings in