Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Jeremy P. Wood"'
Autor:
Sagar S. Matharu, Cassidy S. Nordmann, Kurtis R. Ottman, Rahul Akkem, Douglas Palumbo, Denzel R. D. Cruz, Kenneth Campbell, Gail Sievert, Jamie Sturgill, James Z. Porterfield, Smita Joshi, Hammodah R. Alfar, Chi Peng, Irina D. Pokrovskaya, Jeffrey A. Kamykowski, Jeremy P. Wood, Beth Garvy, Maria A. Aronova, Sidney W. Whiteheart, Richard D. Leapman, Brian Storrie
Publikováno v:
Platelets, Vol 34, Iss 1 (2023)
AbstractPlatelets contribute to COVID-19 clinical manifestations, of which microclotting in the pulmonary vasculature has been a prominent symptom. To investigate the potential diagnostic contributions of overall platelet morphology and their α-gran
Externí odkaz:
https://doaj.org/article/568668bf99a4473e9c0e48d15d0ffc3d
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Antithrombotic therapy is a delicate balance between the benefits of preventing a thrombotic event and the risks of inducing a major bleed. Traditional approaches have included antiplatelet and anticoagulant medications, require careful dosing and mo
Externí odkaz:
https://doaj.org/article/19c8052004214452a573e39ed1ee49ab
Autor:
Muhammad H. Gul, Zin Mar Htun, Vinicio de Jesus Perez, Muhammad Suleman, Samiullah Arshad, Muhammad Imran, Mahender Vyasabattu, Jeremy P. Wood, Michael Anstead, Peter E. Morris
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Objectives To investigate whether COVID-19 patients with pulmonary embolism had higher mortality and assess the utility of d-dimer in predicting acute pulmonary embolism. Patients and methods Using the National Collaborative COVID-19 retrosp
Externí odkaz:
https://doaj.org/article/0eb86447f8d44a23a185ba93883d239a
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 6, Iss 4, Pp n/a-n/a (2022)
Abstract Background Traumatic brain injury (TBI) results in neurovascular damage that initiates intrinsic mechanisms of hypercoagulation, which can contribute to the development of life‐threatening complications, such as coagulopathy and delayed th
Externí odkaz:
https://doaj.org/article/d545223b28be42b1a85f87eb36479cd0
Publikováno v:
Blood Advances, Vol 1, Iss 27, Pp 2692-2702 (2017)
Abstract: Tissue factor pathway inhibitor α (TFPIα) inhibits prothrombinase, the thrombin-generating complex of factor Xa (FXa) and factor Va (FVa), during the initiation of coagulation. This inhibition requires binding of a conserved basic region
Externí odkaz:
https://doaj.org/article/b80cab3955024d39919b18c5139417a1
Publikováno v:
Blood Advances, Vol 1, Iss 6, Pp 386-395 (2017)
Abstract: Activated factor V (FVa) and factor X (FXa) form prothrombinase, which converts prothrombin to thrombin. The α isoform of tissue factor pathway inhibitor (TFPI) dampens early procoagulant events, partly by interacting with FV. FV Leiden (F
Externí odkaz:
https://doaj.org/article/b04ab5d3b319450f8c1338912aeb1738
Autor:
Martha M S, Sim, Meenakshi, Banerjee, Thein, Myint, Beth A, Garvy, Sidney W, Whiteheart, Jeremy P, Wood
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 90:463-471
HIV-1 infection is associated with multiple procoagulant changes and increased thrombotic risk. Possible mechanisms for this risk include heigthened expression of procoagulant tissue factor (TF) on circulating monocytes, extracellular vesicles, and v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34b2c3b1970e883302ffd7c7e31350b9
https://doi.org/10.1097/qai.0000000000002994
https://doi.org/10.1097/qai.0000000000002994
Autor:
Ruth R. Wexler, Kenneth G. Mann, Leonard M. Milstone, Rodney M. Camire, Jeremy P. Wood, Wolfram Ruf, Robert M. Knabb, Richard C. Becker, Craig M Jackson
Publikováno v:
Journal of Thrombosis and Thrombolysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90df0cfa476016d56b01c7183ae509bc
http://europepmc.org/articles/PMC8506080
http://europepmc.org/articles/PMC8506080
Autor:
Irina D. Pokrovskaya, Gunnar Pejler, Joshua Lykins, Subershan Wigna‐Kumar, Harry Amuguni Chanzu, Jeremy P. Wood, Sidney W. Whiteheart, Smita Joshi, Brian Storrie
Publikováno v:
Journal of Thrombosis and Haemostasis. 19:1082-1095
Background Serglycin (SRGN) is an intragranular, sulfated proteoglycan in hematopoietic cells that affects granule composition and function. Objective To understand how SRGN affects platelet granule packaging, cargo release, and extra-platelet microe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::853eea70a4f20096b7bcb6a8814e014b
https://doi.org/10.1111/jth.15243
https://doi.org/10.1111/jth.15243
Autor:
Congqing Wu, Yan Zhang, Lan Li, Ankit Pandeya, Guoying Zhang, Jian Cui, Daniel Kirchhofer, Jeremy P Wood, Susan S Smyth, Yinan Wei, Zhenyu Li
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42
Background: Histones are cationic nuclear proteins that are essential for the structure andfunctions of eukaryotic chromatin. However, extracellular histones trigger inflammatoryresponses and contribute to death in sepsis by unknown mechanisms. We re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f88ad1092505fa1724d0ca95520c9281
https://doi.org/10.1161/atvb.42.suppl_1.487
https://doi.org/10.1161/atvb.42.suppl_1.487