Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jeremy P. Huynh"'
Autor:
Christian M. Harding, Mohamed A. Nasr, Nichollas E. Scott, Guillaume Goyette-Desjardins, Harald Nothaft, Anne E. Mayer, Sthefany M. Chavez, Jeremy P. Huynh, Rachel L. Kinsella, Christine M. Szymanski, Christina L. Stallings, Mariela Segura, Mario F. Feldman
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Bioconjugation is a promising process to manufacture conjugate vaccines, but currently employed enzymes cannot generate the full spectrum of bacterial glycoproteins. Here, the authors use an O-linking oligosaccharyltransferase to generate a polyvalen
Externí odkaz:
https://doaj.org/article/def4f3d9176a44dbb8129ca597b1866c
Autor:
Christina L. Stallings, Christine M. Szymanski, Christian M. Harding, Anne E. Mayer, Mario F. Feldman, Harald Nothaft, Sthefany M. Chavez, Guillaume Goyette-Desjardins, Jeremy P. Huynh, Rachel L. Kinsella, Nichollas E. Scott, Mohamed Adel Nasr, Mariela Segura
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications
Nature Communications
Chemical synthesis of conjugate vaccines, consisting of a polysaccharide linked to a protein, can be technically challenging, and in vivo bacterial conjugations (bioconjugations) have emerged as manufacturing alternatives. Bioconjugation relies upon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa9d6c1156d66addc38995515b791043
https://doaj.org/article/def4f3d9176a44dbb8129ca597b1866c
https://doaj.org/article/def4f3d9176a44dbb8129ca597b1866c
Autor:
William B Messer, Boyd Yount, Kari E Hacker, Eric F Donaldson, Jeremy P Huynh, Aravinda M de Silva, Ralph S Baric
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 6, Iss 2, p e1486 (2012)
Dengue viruses (DENV) are enveloped single-stranded positive-sense RNA viruses transmitted by Aedes spp. mosquitoes. There are four genetically distinct serotypes designated DENV-1 through DENV-4, each further subdivided into distinct genotypes. The
Externí odkaz:
https://doaj.org/article/2c28051283544cb08e496065d0e40d2d
Autor:
Reshma Taneja, Casey T. Weaver, Nicholas N. Jarjour, Jacqueline M. Kimmey, Irina Shchukina, Brian T. Edelson, Tara R. Bradstreet, Jeremy P. Huynh, Chih-Chung Lin, Oleg Shpynov, Maxim N. Artyomov, Christina L. Stallings, Elizabeth A. Schwarzkopf
Publikováno v:
The Journal of experimental medicine, vol 215, iss 7
The Journal of Experimental Medicine
The Journal of Experimental Medicine
This study demonstrates that the transcription factor basic helix-loop-helix family member e40 (Bhlhe40) is essential during Mycobacterium tuberculosis infection to specifically regulate Il10 expression, revealing the importance of strict control of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc81d9906c211e9a72d3e6d9868fcf11
https://doi.org/10.1084/jem.20171704
https://doi.org/10.1084/jem.20171704
Autor:
Scott A. Handley, Denise M. Monack, Ta-Chiang Liu, Paul M. Allen, Vladimir E. Diaz-Ochoa, Jonathan Dworkin, Tobias Kerrinnes, Erica L. Sennott, Caihong Wang, Jacqueline M. Kimmey, Renée M. Tsolis, Kelly M. Storek, Gaya K. Amarasinghe, Chandni Desai, Eric Chen, Ashley A. Viehmann Milam, Michael N. Starnbach, Guoyan Zhao, Camaron R. Hole, Jeremy P. Huynh, Christina L. Stallings, Daisy W. Leung, Craig A. Micchelli, Indira U. Mysorekar, Tamara L. Doering, Christine C. Yokoyama, Rachel A. Idol, Sunmin Park, Seungmin Hwang, Mary C. Dinauer, Megan T. Baldridge, Herbert W. Virgin
Publikováno v:
Journal of Biological Chemistry. 293:6022-6038
Germline-encoded receptors recognizing common pathogen-associated molecular patterns are a central element of the innate immune system and play an important role in shaping the host response to infection. Many of the innate immune molecules central t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37373c955333a5bd97b1c06e5cbba390
https://doi.org/10.1074/jbc.ra117.001246
https://doi.org/10.1074/jbc.ra117.001246
Autor:
Sharmila Nair, Vicky Lampropoulou, Ekaterina Esaulova, Anshu P. Gounder, Maxim N. Artyomov, Adrianus C. M. Boon, Michael S. Diamond, Elizabeth A. Schwarzkopf, Ekaterina Loginicheva, Tara R. Bradstreet, Brian T. Edelson, Jeremy P. Huynh, Christina L. Stallings
Publikováno v:
The Journal of Experimental Medicine
Nair et al. define a key role for Irg1 in minimizing the pathological immune response associated with Mtb infection. Using Irg1−/− and Irg1fl/fl conditional mice, detailed immune cell analysis, and transcriptional profiling, their data supports a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3b7b64bf1bf436ce79642fedccf62bd
http://europepmc.org/articles/PMC5881474
http://europepmc.org/articles/PMC5881474
Autor:
Michael L. Mallory, Jacob Kocher, J. Edward Gates, Lisa C. Lindesmith, Anne Beall, Eric F. Donaldson, Kari Debbink, Ralph S. Baric, Jeremy P. Huynh, Boyd Yount, Rachel L. Graham
Publikováno v:
mBio
mBio, Vol 9, Iss 3 (2018)
mBio, Vol 9, Iss 3, p e00869-18 (2018)
mBio, Vol 9, Iss 3 (2018)
mBio, Vol 9, Iss 3, p e00869-18 (2018)
Emerging zoonotic viral diseases remain a challenge to global public health. Recent surveillance studies have implicated bats as potential reservoirs for a number of viral pathogens, including coronaviruses and Ebola viruses. Caliciviridae represent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1866ef6245e8b89cad982f3c4f0445a4
https://doi.org/10.1128/mbio.00869-18
https://doi.org/10.1128/mbio.00869-18
Autor:
Christine C, Yokoyama, Megan T, Baldridge, Daisy W, Leung, Guoyan, Zhao, Chandni, Desai, Ta-Chiang, Liu, Vladimir E, Diaz-Ochoa, Jeremy P, Huynh, Jacqueline M, Kimmey, Erica L, Sennott, Camaron R, Hole, Rachel A, Idol, Sunmin, Park, Kelly M, Storek, Caihong, Wang, Seungmin, Hwang, Ashley, Viehmann Milam, Eric, Chen, Tobias, Kerrinnes, Michael N, Starnbach, Scott A, Handley, Indira U, Mysorekar, Paul M, Allen, Denise M, Monack, Mary C, Dinauer, Tamara L, Doering, Renee M, Tsolis, Jonathan E, Dworkin, Christina L, Stallings, Gaya K, Amarasinghe, Craig A, Micchelli, Herbert W, Virgin
Publikováno v:
The Journal of biological chemistry. 293(16)
Germline-encoded receptors recognizing common pathogen-associated molecular patterns are a central element of the innate immune system and play an important role in shaping the host response to infection. Many of the innate immune molecules central t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dbc8e8875fab2d72791c4ef269563bb0
https://pubmed.ncbi.nlm.nih.gov/29496999
https://pubmed.ncbi.nlm.nih.gov/29496999
Autor:
Scott W. Wong, Alfred W. Legasse, Michael K. Axthelm, Shannon L. Planer, Anne D. Lewis, Minsha Manoharan, Jeremy P. Huynh, Margo A. Brinton, Stephanie Rawlings, Eric F. Donaldson, Ralph S. Baric, Mary F. Dickerson, Jerilyn K. Pecotte, Lois M. A. Colgin, Heather A. Vatter
Publikováno v:
Virology
Simian hemorrhagic fever virus is an arterivirus that naturally infects species of African nonhuman primates causing acute or persistent asymptomatic infections. Although it was previously estimated that 1% of baboons are SHFV-positive, more than 10%
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6befa8aaa7337fb2cd4e85b7e8ae796
Autor:
Everardo Vega, Eric F. Donaldson, Jeremy P. Huynh, Ben Lopman, Leslie Barclay, Ralph S. Baric, Jan Vinjé, Luke F. Chen
Publikováno v:
Journal of Virology
Noroviruses are the leading cause of acute gastroenteritis outbreaks worldwide. The majority of norovirus outbreaks are caused by genogroup II.4 (GII.4). Novel GII.4 strains emerge every 2 to 4 years and replace older variants as the dominant norovir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff53108ea9360642df68a2b6bac5ef0c
https://doi.org/10.1128/jvi.02494-14
https://doi.org/10.1128/jvi.02494-14