Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jeremy Nix"'
Publikováno v:
ACI open
Background We offered adolescents personalized choices about the type of genetic results they wanted to learn during a research study and created a workflow to filter and transfer the results to the electronic health record (EHR). Methods We describe
Autor:
Batsal Devkota, Michal Kouril, Joseph W. St. Geme, Alba Gutierrez, Simone Temporal, Keith Marsolo, Peter White, Joseph A. Majzoub, Alan Yen, Jaspreet Khanna, Julie Wijesooriya, Mike Furgason, Florence T. Bourgeois, Christopher Geehan, Adda Grimberg, Arnold W. Strauss, Becca Harper, Kristen Safier, Aleksandr Nikitin, Andrew Wooten, Vidhu V Thaker, Deanne Taylor, Ingo Helbig, Darlene Barkman, Anil Kumar Degala, Gelvina Stevenson, Eric D. Marsh, Colin P. Hawkes, Andrew Dauber, Jason Stedman, In-Hee Lee, Andrew M. Rupert, Gary R. Fleisher, Ramkrishna Chakrabarty, Piotr Sliz, Alyssa Ellis, Barbara Hallinan, Kenneth D. Mandl, Susan Kornetsky, Bryan A. Wolf, Philip Dexheimer, Alan H. Beggs, Yu Zhang, Erin M. Borglund, Joel N. Hirschhorn, Andrew Joseph Guidetti, Amy Schwarzhoff, Anna Poduri, Gabor Korodi, Louis J. Muglia, Prakash Velayutham, Christopher P. Kirby, Mike Pistone, Allison Heath, Parth Divekar, Judson Kilbourn, Ranjay Kumar, Guillaume Labilloy, Alka Chandel, Ian D. Krantz, Thomas N DeSain, Kristen L. Sund, Lisa J. Martin, James Morgan, Jeremy Nix, Sawona Biswas, Tracy A. Glauser, Paul Avillach, Sek Won Kong, Niloofar Jalali, Jeremy J. Corsmo, Anna Bartels, Amy Kratchman, Bria Morgan
Publikováno v:
Genetics in Medicine
Purpose Clinicians and researchers must contextualize a patient’s genetic variants against population-based references with detailed phenotyping. We sought to establish globally scalable technology, policy, and procedures for sharing biosamples and
Autor:
Naoya Aoki, Pritam Das, Mitsuru Shinohara, Joseph E. Parisi, Ronald C. Petersen, Jeremy Nix, Shunsuke Koga, Guojun Bu, Dennis W. Dickson, Terrone L. Rosenberry, Takuya Konno, Motoko Shinohara
Publikováno v:
Brain. 140:3301-3316
Accumulation of amyloid-β peptides is a dominant feature in the pathogenesis of Alzheimer's disease; however, it is not clear how individual amyloid-β species accumulate and affect other neuropathological and clinical features in the disease. Thus,
Autor:
Kenneth D. Mandl, Tracy Glauser, Ian D. Krantz, Paul Avillach, Anna Bartels, Alan H. Beggs, Sawona Biswas, Florence T. Bourgeois, Jeremy Corsmo, Andrew Dauber, Batsal Devkota, Gary R. Fleisher, Allison P. Heath, Ingo Helbig, Joel N. Hirschhorn, Judson Kilbourn, Sek Won Kong, Susan Kornetsky, Joseph A. Majzoub, Keith Marsolo, Lisa J. Martin, Jeremy Nix, Amy Schwarzhoff, Jason Stedman, Arnold Strauss, Kristen L. Sund, Deanne M. Taylor, Peter S. White, Eric Marsh, Adda Grimberg, Colin Hawkes, Darlene Barkman, Erin M. Borglund, Ramkrishna Chakrabarty, Alka Chandel, Anil Kumar Degala, Thomas DeSain, Philip Dexheimer, Parth Divekar, Alyssa Ellis, Mike Furgason, Christopher Geehan, Andrew Joseph Guidetti, Alba Gutierrez, Barbara Hallinan, Becca Harper, Niloofar Jalali, Jaspreet Khanna, Christopher Kirby, Gabor Korodi, Michal Kouril, Amy Kratchman, Ranjay Kumar, Guillaume Labilloy, In-Hee Lee, Bria Morgan, James Morgan, Louis J Muglia, Aleksandr Nikitin, Mike Pistone, Anna Poduri, Andrew Rupert, Kristen Safier, Piotr Sliz, Gelvina Stevenson, Joseph St. Geme, Vidhu Thaker, Simone Temporal, Prakash Velayutham, Julie Wijesooriya, Bryan Wolf, Andrew Wooten, Alan Yen, Yu Zhang
Publikováno v:
Genetics in Medicine
Clinicians and researchers must contextualize a patient's genetic variants against population-based references with detailed phenotyping. We sought to establish globally scalable technology, policy, and procedures for sharing biosamples and associate
Autor:
Patricia K. Martin, A. Jeremy Nix, Anant K. Paravastu, Danting Huang, Terrone L. Rosenberry, Maxwell I. Zimmerman
Publikováno v:
Journal of Molecular Biology. 427:2319-2328
Understanding the molecular structures of amyloid-β (Aβ) oligomers and underlying assembly pathways will advance our understanding of Alzheimer's disease (AD) at the molecular level. This understanding could contribute to disease prevention, diagno
Autor:
Ahna Lh Pai, Keith Marsolo, Caroline F. Morrison, Larry L. Mullins, Jeremy Nix, William Shuman
Publikováno v:
JMIR Research Protocols
Background: Parents of children newly diagnosed with cancer are confronted with multiple stressors that place them at risk for significant psychological distress. One strategy that has been shown to help reduce uncertainty is the provision of basic i
Challenges in creating an opt-in biobank with a registrar-based consent process and a commercial EHR
Autor:
Jeremy J. Corsmo, Rajesh Ganta, Keith Marsolo, Christopher Smith, Jamie Chalfin, Carrie Pollick, Michael G. Barnes, Jeremy Nix
Publikováno v:
Journal of the American Medical Informatics Association : JAMIA
Residual clinical samples represent a very appealing source of biomaterial for translational and clinical research. We describe the implementation of an opt-in biobank, with consent being obtained at the time of registration and the decision stored i
Autor:
Scott A. Snyder, Ren Xiang Tan, Terrone L. Rosenberry, Patricia K. Martin, A. Jeremy Nix, Jonah Cheung, Scott A. Wildman
Natural product inhibitors of AChE are of interest both because they offer promise as inexpensive drugs for symptomatic relief in Alzheimer's disease and because they may provide insights into the structural features of the AChE catalytic site. Hopea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b29717daebeffbc25d41943e234869c
https://europepmc.org/articles/PMC5136322/
https://europepmc.org/articles/PMC5136322/
Autor:
A. Jeremy Nix, William M. Tay, Jennifer G. Bryant, Patricia K. Martin, Bernadette Cusack, Terrone L. Rosenberry
Publikováno v:
Biochemistry. 51:3759-3766
Endogenous amyloid-β (Aβ) oligomeric aggregates have been proposed as toxic agents in Alzheimer's disease (AD). Knowledge of their structures not only may provide insight into the basis of their neurotoxicities but also may reveal new targets for t
Autor:
Tay, William M., Bryant, Jennifer G., Martin, Patricia K., Jeremy Nix, A., Cusack, Bernadette M., Rosenberry, Terrone L.
Publikováno v:
Biochemistry; 5/8/2012, Vol. 51 Issue 18, p3759-3766, 8p