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pro vyhledávání: '"Jeremy N. Bradbeer"'
Autor:
Jeremy N. Bradbeer, Rasesh D. Kapadia, George B. Stroup, Susanta K. Sarkar, Alison M. Badger, Barbara A. Swift, Hugh Zhao, David J. Rieman
Publikováno v:
Arthritis & Rheumatism. 39:504-514
Objective. To evaluate the effect of SK&F 106615 on joint integrity in rats with adjuvant-induced arthritis (AIA). Methods. AIA was induced in Lewis rats on day 0, and the animals were treated either prophylactically (days 0–16 or days 0–23) or t
Autor:
Paola Misiano, Jeremy N. Bradbeer, Xiaoguang Liang, Maurizio Valente, Luciano Visentin, Sergio Oneta, R.A. Dodds, Maxine Gowen, Carlo Farina
Publikováno v:
Scopus-Elsevier
A potent and selective inhibitor of the osteoclastic V-H(+)-ATPase, (2Z,4E)-5-(5,6-dichloro-2-indolyl)-2-methoxy-N-(1,2,2,6, 6-pentamethylpiperidin-4-yl)-2,4-pentadienamide (SB 242784), was evaluated in two animal models of bone resorption. SB 242784