Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Jeremy Metz"'
Publikováno v:
Biology Open, Vol 12, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/680bd308a460453fb69bc79c24e309d1
Autor:
Olivia Goode, Ashley Smith, Ashraf Zarkan, Jehangir Cama, Brandon M. Invergo, Daaniyah Belgami, Santiago Caño-Muñiz, Jeremy Metz, Paul O’Neill, Aaron Jeffries, Isobel H. Norville, Jonathan David, David Summers, Stefano Pagliara
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
ABSTRACT Persister and viable but non-culturable (VBNC) cells are two clonal subpopulations that can survive multidrug exposure via a plethora of putative molecular mechanisms. Here, we combine microfluidics, time-lapse microscopy, and a plasmid-enco
Externí odkaz:
https://doaj.org/article/6d1f31061d5a4954937de418453ed324
Autor:
Sulayman Mourabit, Jennifer A. Fitzgerald, Robert P. Ellis, Aya Takesono, Cosima S. Porteus, Maciej Trznadel, Jeremy Metz, Matthew J. Winter, Tetsuhiro Kudoh, Charles R. Tyler
Publikováno v:
Environment International, Vol 133, Iss , Pp - (2019)
Background: Reactive oxygen species (ROS) arise as a result from, and are essential in, numerous cellular processes. ROS, however, are highly reactive and if left unneutralised by endogenous antioxidant systems, can result in extensive cellular damag
Externí odkaz:
https://doaj.org/article/15d294de008a404fa72c8868d401fd3d
Autor:
Jonathan P. Evans, Jeremy Metz, Rahul Anaspure, William J. Thomas, Andrew King, Vicki A. Goodwin, Chris D. Smith
Publikováno v:
Journal of Experimental Orthopaedics, Vol 5, Iss 1, Pp 1-8 (2018)
Abstract Background Injections into the tendinous portion of the common extensor origin are a common intervention in the treatment of Lateral Elbow Tendinopathy (LET). Clinical trials report a heterogeneous selection of injectate volumes and delivery
Externí odkaz:
https://doaj.org/article/f368e39cdc504974a38dd40e71f103bb
Autor:
Rosemary A. Bamford, Ashley Smith, Jeremy Metz, Georgina Glover, Richard W. Titball, Stefano Pagliara
Publikováno v:
BMC Biology, Vol 15, Iss 1, Pp 1-12 (2017)
Abstract Background Clonal microbial populations often harbor rare phenotypic variants that are typically hidden within the majority of the remaining cells, but are crucial for the population’s resilience to external perturbations. Persister and vi
Externí odkaz:
https://doaj.org/article/2283628220054f6e8b6037028c70d1b9
Autor:
Jack W. C. Chen, Zhuo A. Chen, Kacper B. Rogala, Jeremy Metz, Charlotte M. Deane, Juri Rappsilber, James G. Wakefield
Publikováno v:
Biology Open, Vol 6, Iss 5, Pp 654-663 (2017)
The hetero-octameric protein complex, Augmin, recruits γ-Tubulin ring complex (γ-TuRC) to pre-existing microtubules (MTs) to generate branched MTs during mitosis, facilitating robust spindle assembly. However, despite a recent partial reconstitutio
Externí odkaz:
https://doaj.org/article/12de2de42a50405e8c6a3f02e5c55981
Autor:
Rikke Brandstrup Morrish, Michael Hermes, Jeremy Metz, Nicholas Stone, Stefano Pagliara, Richard Chahwan, Francesca Palombo
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
The dynamic architecture of chromatin, the macromolecular complex comprised primarily of DNA and histones, is vital for eukaryotic cell growth. Chemical and conformational changes to chromatin are important markers of functional and developmental pro
Externí odkaz:
https://doaj.org/article/41eca15b4b504a02b19105d2b6ece3ea
Autor:
Monika Bokori-Brown, Jeremy Metz, Peter G. Petrov, Francis Mussai, Carmela De Santo, Neil J. Smart, Sarah Saunders, Bridget Knight, Ira Pastan, Richard W. Titball, C. Peter Winlove
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
Acute Lymphoblastic Leukemia (ALL) remains the most frequent cause of cancer-related mortality in children and novel therapies are needed for the treatment of relapsed/refractory childhood ALL. One approach is the targeting of ALL blasts with the Pse
Externí odkaz:
https://doaj.org/article/fd5f37bb2a274ab29288d9ff4093e7cc
Autor:
Congping Lin, Martin Schuster, Sofia Cunha Guimaraes, Peter Ashwin, Michael Schrader, Jeremy Metz, Christian Hacker, Sarah Jane Gurr, Gero Steinberg
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
The mechanisms underlying the positioning of eukaryotic organelles remain elusive. Here Lin et al. use imaging and a mathematical model to show that microtubule-based transport and active diffusion and actin-based polar drift act together to facilita
Externí odkaz:
https://doaj.org/article/bbd6d036c48243b1b66504db2d372bae
Autor:
Yunhong Wang, Jeremy Metz, Joseph L Costello, Josiah Passmore, Michael Schrader, Christian Schultz, Markus Islinger
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0209507 (2018)
Peroxisomes can be frequently found in proximity to other subcellular organelles such as the endoplasmic reticulum (ER), mitochondria or lysosomes. The tail-anchored protein ACBD5 was recently identified as part of a tethering complex at peroxisome-E
Externí odkaz:
https://doaj.org/article/463161190464436ea07898e1c5226559