Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Jeremy Mark Wilkinson"'
Autor:
Catherine Hewitt, Abhishek Abhishek, Paul Emery, Laura Mandefield, Amar Rangan, Helena Marzo-Ortega, Joy Adamson, Johanna Taylor, Susan Shepherd, Sarah Ronaldson, Jeremy Mark Wilkinson, Laura Coates, Bernard Van Duren, James Maxwell, Hemant Pandit, Jagdeep Nanchahal, Jinshuo Li, Duncan Richards, Samantha Brady, Andrew Mott, Katie Carlisle, Susan Marion Goodman, Gillian Parkinson, Kulveer Singh Mankia
Publikováno v:
BMJ Open, Vol 14, Iss 6 (2024)
Introduction Biological disease-modifying antirheumatic drugs (bDMARDs) have revolutionised the treatment of inflammatory arthritis (IA). However, many people with IA still require planned orthopaedic surgery to reduce pain and improve function. Curr
Externí odkaz:
https://doaj.org/article/fd658c2b0bbd467bb464221453418580
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Nutritional rickets is an important disease in global health. Although nutritional rickets commonly manifests as bony deformities, there is an increased risk of life-threatening seizures secondary to hypocalcaemia. Dietary vitamin D deficiency is ass
Externí odkaz:
https://doaj.org/article/94e02af1329940c8bf22b238b195aec9
Autor:
George A. E. Pickering, Favour Felix-Ilemhenbhio, Matthew J. Clark, Klaudia Kocsy, Jonathan Simpson, Ilaria Bellantuono, Alison Gartland, Jeremy Mark Wilkinson, Konstantinos Hatzikotoulas, Endre Kiss-Toth
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 16, p 9203 (2022)
The formation of pathological bone deposits within soft tissues, termed heterotopic ossification (HO), is common after trauma. However, the severity of HO formation varies substantially between individuals, from relatively isolated small bone islands
Externí odkaz:
https://doaj.org/article/f144f185821b4d7ebe3d1a6fff61447b
Autor:
Jonathan Thomas Evans, Sofia Mouchti, Ashley William Blom, Jeremy Mark Wilkinson, Michael Richard Whitehouse, Andrew Beswick, Andrew Judge
Publikováno v:
PLoS Medicine, Vol 18, Iss 7, p e1003704 (2021)
BackgroundOne in 10 people in the United Kingdom will need a total knee replacement (TKR) during their lifetime. Access to this life-changing operation has recently been restricted based on body mass index (BMI) due to belief that high BMI may lead t
Externí odkaz:
https://doaj.org/article/59118fac814b43158cea3a11d336735f
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 6983 (2022)
The term heterotopic ossification (HO) describes bone formation in tissues where bone is normally not present. Musculoskeletal trauma induces signalling events that in turn trigger cells, probably of mesenchymal origin, to differentiate into bone. Th
Externí odkaz:
https://doaj.org/article/82283c7285fd4397b8f7b51c0c36ec3e
Autor:
Mohsen Farzi, Jose M. Pozo, Eugene McCloskey, Richard Eastell, Nicholas C. Harvey, Alejandro F. Frangi, Jeremy Mark Wilkinson
Publikováno v:
Journal of Bone and Mineral Research. 37:1679-1688
The risk of osteoporotic fracture is inversely related to bone mineral density (BMD), but how spatial BMD pattern influences fracture risk remains incompletely understood. This study used a pixel-level spatiotemporal atlas of proximal femoral BMD in
Autor:
George A E, Pickering, Favour, Felix-Ilemhenbhio, Matthew J, Clark, Klaudia, Kocsy, Jonathan, Simpson, Ilaria, Bellantuono, Alison, Gartland, Jeremy Mark, Wilkinson, Konstantinos, Hatzikotoulas, Endre, Kiss-Toth
Publikováno v:
International journal of molecular sciences. 23(16)
The formation of pathological bone deposits within soft tissues, termed heterotopic ossification (HO), is common after trauma. However, the severity of HO formation varies substantially between individuals, from relatively isolated small bone islands
Autor:
Eleftheria Zeggini, D Swift, Julia Steinberg, Roger A. Brooks, Raveen L Jayasuriya, Karan M. Shah, Andreas Fontalis, Jeremy Mark Wilkinson, Andrew McCaskie, Lorraine Southam, M.J. Clark
Publikováno v:
Ann. Rheum. Dis. 80, 1070-1074 (2021)
Annals of the Rheumatic Diseases
Annals of the Rheumatic Diseases
ObjectivesTo determine how gene expression profiles in osteoarthritis joint tissues relate to patient phenotypes and whether molecular subtypes can be reproducibly captured by a molecular classification algorithm.MethodsWe analysed RNA sequencing dat
Autor:
Andrew Gordon, David J. Hughes, Mohit M Mahatma, Raveen L Jayasuriya, Jeremy Mark Wilkinson, Andrew J. Hamer, Richard Eastell, R. M. Kerry, SC Buckley, Mohammed W Tomouk, Nigel Hoggard
Publikováno v:
The Lancet Rheumatology. 3:e195-e203
Summary Background Osteolysis causes recurrent pain and disability after total hip arthroplasty. We investigated the effect of the human monoclonal antibody denosumab on osteolytic lesion activity in patients undergoing revision total hip arthroplast
Autor:
John Loughlin, Unnur Styrkarsdottir, Jeremy Mark Wilkinson, Cindy G. Boer, Lorraine Southam, Ingrid Meulenbelt, Eleftheria Zeggini, Kathleen Cheung, Mariel Young, Terence D. Capellini, Sarah J. Rice, Michelle S. Yau, Joyce B. J. van Meurs, David T. Felson, Linda Broer, André G. Uitterlinden, Rodrigo Coutinho de Almeida
Publikováno v:
Annals of the Rheumatic Diseases, 80(3), 367-375. BMJ Publishing Group
Annals of the Rheumatic Diseases, 80(3), 367-375. BMJ PUBLISHING GROUP
Ann. Rheum. Dis. 80, 367–375 (2021)
Annals of the Rheumatic Diseases, 80(3), 367-375. BMJ PUBLISHING GROUP
Ann. Rheum. Dis. 80, 367–375 (2021)
BackgroundDespite recent advances in the understanding of the genetic architecture of osteoarthritis (OA), only two genetic loci have been identified for OA of the hand, in part explained by the complexity of the different hand joints and heterogenei