Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jeremy M T J, Dennison"'
Autor:
Eugenii A. Rabiner, Ayla Mansur, Wei Yin, Terry Brown, Graham E. Searle, Tolga Uz, Joy Atienza, Johannes Tauscher, Jeremy M. T. J. Dennison, Jan Passchier, Jingtao Wu, Roger N. Gunn, Grace Chen, Adam J. Schwarz, Yvonne Lewis
Publikováno v:
Neuropsychopharmacology. 47:1405-1412
The use of positron emission tomography (PET) in early-phase development of novel drugs targeting the central nervous system, is well established for the evaluation of brain penetration and target engagement. However, when novel targets are involved
Autor:
Maciej J, Zamek-Gliszczynski, David, Kenworthy, David A, Bershas, Mitesh, Sanghvi, Adrian I, Pereira, Jennypher, Mudunuru, Lee, Crossman, Jill L, Pirhalla, Karl M, Thorpe, Jeremy M T J, Dennison, Megan M, McLaughlin, Matthew, Allinder, Brandon, Swift, Robin L, O'Connor-Semmes, Graeme C, Young
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 49(12)
Linerixibat, an oral small-molecule ileal bile acid transporter inhibitor under development for cholestatic pruritus in primary biliary cholangitis, was designed for minimal absorption from the intestine (site of pharmacological action). This study c
Autor:
Eugenii A, Rabiner, Tolga, Uz, Ayla, Mansur, Terry, Brown, Grace, Chen, Jingtao, Wu, Joy, Atienza, Adam J, Schwarz, Wei, Yin, Yvonne, Lewis, Graham E, Searle, Jeremy M T J, Dennison, Jan, Passchier, Roger N, Gunn, Johannes, Tauscher
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 47(7)
The use of positron emission tomography (PET) in early-phase development of novel drugs targeting the central nervous system, is well established for the evaluation of brain penetration and target engagement. However, when novel targets are involved