Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jeremy L Baryza"'
Autor:
Susanne Müller, Suzanne Ackloo, Cheryl H Arrowsmith, Marcus Bauser, Jeremy L Baryza, Julian Blagg, Jark Böttcher, Chas Bountra, Peter J Brown, Mark E Bunnage, Adrian J Carter, David Damerell, Volker Dötsch, David H Drewry, Aled M Edwards, James Edwards, Jon M Elkins, Christian Fischer, Stephen V Frye, Andreas Gollner, Charles E Grimshaw, Adriaan IJzerman, Thomas Hanke, Ingo V Hartung, Steve Hitchcock, Trevor Howe, Terry V Hughes, Stefan Laufer, Volkhart MJ Li, Spiros Liras, Brian D Marsden, Hisanori Matsui, John Mathias, Ronan C O'Hagan, Dafydd R Owen, Vineet Pande, Daniel Rauh, Saul H Rosenberg, Bryan L Roth, Natalie S Schneider, Cora Scholten, Kumar Singh Saikatendu, Anton Simeonov, Masayuki Takizawa, Chris Tse, Paul R Thompson, Daniel K Treiber, Amélia YI Viana, Carrow I Wells, Timothy M Willson, William J Zuercher, Stefan Knapp, Anke Mueller-Fahrnow
Publikováno v:
eLife, Vol 7 (2018)
Potent, selective and broadly characterized small molecule modulators of protein function (chemical probes) are powerful research reagents. The pharmaceutical industry has generated many high-quality chemical probes and several of these have been mad
Externí odkaz:
https://doaj.org/article/959198e7fd31440495c0d4c7cf3c5c06
Autor:
David H. Drewry, Steve Hitchcock, Volker Dötsch, Ingo Hartung, Brian D. Marsden, Hisanori Matsui, C. Bountra, Carrow I. Wells, Marcus Bauser, Stefan Knapp, Volkhart Mj Li, Amélia Yi Viana, Christian Fischer, Mathias John Paul, Adrian Carter, Spiros Liras, Julian Blagg, Mark Edward Bunnage, Suzanne Ackloo, Adriaan P. IJzerman, Susanne Müller, Stephen V. Frye, Saul H Rosenberg, Natalie S Schneider, Daniel K Treiber, Andreas Gollner, David R. Damerell, Cora Scholten, Bryan L. Roth, Cheryl H. Arrowsmith, Charles E. Grimshaw, Aled M. Edwards, Kumar Singh Saikatendu, Timothy M. Willson, Jeremy L Baryza, Thomas Hanke, Masayuki Takizawa, Peter Brown, Terry V Hughes, James P. Edwards, Daniel Rauh, Trevor Howe, Anke Mueller-Fahrnow, Ronan C. O'Hagan, Chris Tse, Vineet Pande, Anton Simeonov, Paul R. Thompson, Dafydd R. Owen, J.M. Elkins, Jark Böttcher, William J. Zuercher, Stefan Laufer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d718f899c5ce6099584927eb7f1b37e
https://doi.org/10.7554/elife.34311.009
https://doi.org/10.7554/elife.34311.009
Autor:
Julian Blagg, David H. Drewry, Steve Hitchcock, Hisanori Matsui, Carrow I. Wells, Daniel Rauh, Anke Mueller-Fahrnow, Ronan C. O'Hagan, Adriaan P. IJzerman, Kumar Singh Saikatendu, Stefan Laufer, Timothy M. Willson, Paul R. Thompson, Chris Tse, Saul H Rosenberg, C. Bountra, Marcus Bauser, Dafydd R. Owen, Brian D. Marsden, Terry V Hughes, Daniel K Treiber, James P. Edwards, Bryan L. Roth, Cheryl H. Arrowsmith, Suzanne Ackloo, J.M. Elkins, Adrian Carter, Spiros Liras, Stefan Knapp, Christian Fischer, Susanne Müller, Amélia Yi Viana, Mathias John Paul, William J. Zuercher, Masayuki Takizawa, Jeremy L Baryza, Thomas Hanke, Peter Brown, David R. Damerell, Cora Scholten, Stephen V. Frye, Anton Simeonov, Mark Edward Bunnage, Charles E. Grimshaw, Andreas Gollner, Aled M. Edwards, Natalie S Schneider, Trevor Howe, Volker Dötsch, Ingo Hartung, Jark Böttcher, Vineet Pande, Volkhart Mj Li
Publikováno v:
eLife, Vol 7 (2018)
eLife
ELIFE, 7, e34311. ELIFE SCIENCES PUBLICATIONS LTD
eLife
ELIFE, 7, e34311. ELIFE SCIENCES PUBLICATIONS LTD
Potent, selective and broadly characterized small molecule modulators of protein function (chemical probes) are powerful research reagents. The pharmaceutical industry has generated many high-quality chemical probes and several of these have been mad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba91100a44a3d9b67ccf3f2841cb55bf
Prolonging microtubule dysruption enhances the immunogenicity of chronic lymphocytic leukaemia cells
Autor:
S. P. Shaha, Liwei He, Jeremy L. Baryza, J. Tomic, David Spaner, T. Pham, J. W. Booth, Paul A. Wender, Y. Shi, D White, P. Mero
Publikováno v:
Clinical and Experimental Immunology. 158:186-198
Summary Cytotoxic chemotherapies do not usually mediate the expression of an immunogenic gene programme in tumours, despite activating many of the signalling pathways employed by highly immunogenic cells. Concomitant use of agents that modulate and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::362a993acbc590ef6c188e64478b9a46
https://doi.org/10.1111/j.1365-2249.2009.04003.x
https://doi.org/10.1111/j.1365-2249.2009.04003.x
Autor:
Jeremy L. Baryza, Paul A. Wender
Publikováno v:
Organic Letters. 7:1177-1180
[structure: see text] The C20 region of our bryostatin analogs was identified as a nonpharmacophoric site that could be varied to tune analogs for function and physical properties without significantly affecting their binding affinity for PKC. The us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1118a4c4eeb05575000a01c882b19790
https://doi.org/10.1021/ol0501931
https://doi.org/10.1021/ol0501931
Autor:
Mark DeBenedette, David Cervi, Paul A. Wender, Andre C. Schuh, Jenny Mena, David Spaner, Caitlin Hammond, Liwei He, Jeremy L. Baryza, Yonghong Shi, Jelena Tomic, Laszlo Radvanyi, Amanda E Millar
Publikováno v:
Journal of Immunotherapy. 28:28-39
Since the intrinsically poor immunogenicity of chronic lymphocytic leukemia (CLL) cells might be a key factor in allowing them to avoid immune control mechanisms, the development of methods to enhance CLL cell immunogenicity might lead to improved di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d8ca06014c88e9b292198b30201a7f9
https://doi.org/10.1097/00002371-200501000-00004
https://doi.org/10.1097/00002371-200501000-00004
Publikováno v:
Biochemical and Biophysical Research Communications. 318:949-954
Intracellularly acting peptide modulators of signaling enzymes provide a powerful means to regulate signaling events. Delivery of peptides into cells is facilitated by conjugation to carrier peptides, such as Tat. When peptides are irreversibly conju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbc8356c8aee1db62dfbbce70c224881
https://doi.org/10.1016/j.bbrc.2004.04.121
https://doi.org/10.1016/j.bbrc.2004.04.121
Autor:
Travis J. Williams, Theodore C. Jessop, Joshua C. Horan, Gabriel G. Gamber, Paul A. Wender, Cindy Kan, Kanaka Pattabiraman, Stacey E. Brenner, Michael O. Clarke, Jeremy L. Baryza
Publikováno v:
Pure and Applied Chemistry. 75:143-155
Studies in our laboratory focus on problems in chemistry (new reactions and syn- thesis), biology (novel modes of action), and medicine (new therapeutic leads and drug deliv- ery systems). These interconnected and often synergistic activities are ins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f59cd3a6c51e21424ac22615aa2d5ba
https://doi.org/10.1351/pac200375020143
https://doi.org/10.1351/pac200375020143
Autor:
Adam J. Schrier, Brian A. DeChristopher, Vishal Verma, Brian Loy, Jeremy L. Baryza, Stacey E. Brenner, Paul A. Wender
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 108(17)
Modern methods for the identification of therapeutic leads include chemical or virtual screening of compound libraries. Nature’s library represents a vast and diverse source of leads, often exhibiting exquisite biological activities. However, the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e29a67e0d5492afb9a6a1742f280edb3
https://pubmed.ncbi.nlm.nih.gov/21415363
https://pubmed.ncbi.nlm.nih.gov/21415363
Autor:
Michael K. Hilinski, Paul A. Wender, Joshua C. Horan, Cindy Kan, Vishal Verma, Jeremy L. Baryza
Publikováno v:
Drug Discovery Research: New Frontiers in the Post-Genomic Era
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28a8ed1ecece89e2e09e5a582520577a
https://doi.org/10.1002/9780470131862.ch6
https://doi.org/10.1002/9780470131862.ch6