Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Jeremy Katzen"'
Autor:
Slaven Crnkovic, Francesco Valzano, Elisabeth Fließer, Jürgen Gindlhuber, Helene Thekkekara Puthenparampil, Maria Basil, Mike P. Morley, Jeremy Katzen, Elisabeth Gschwandtner, Walter Klepetko, Edward Cantu, Heimo Wolinski, Horst Olschewski, Jörg Lindenmann, You-Yang Zhao, Edward E. Morrisey, Leigh M. Marsh, Grazyna Kwapiszewska
Publikováno v:
JCI Insight, Vol 7, Iss 20 (2022)
A central feature of progressive vascular remodeling is altered smooth muscle cell (SMC) homeostasis; however, the understanding of how different cell populations contribute to this process is limited. Here, we utilized single-cell RNA sequencing to
Externí odkaz:
https://doaj.org/article/44b0a9ebfeff415b9c53d340fe872d68
Autor:
Sushila A. Toulmin, Chaitali Bhadiadra, Andrew J. Paris, Jeffrey H. Lin, Jeremy Katzen, Maria C. Basil, Edward E. Morrisey, G. Scott Worthen, Laurence C. Eisenlohr
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Type II alveolar cells play central roles in multiple aspects of lung biology. Here the authors show that type II alveolar cells also constitutively express MHCII, exhibit limited MHCII antigen presentation capacity, and are a component of the host r
Externí odkaz:
https://doaj.org/article/e19c792b6eed4c79a384d45bab80f5de
Autor:
Kseniya Obraztsova, Maria C. Basil, Ryan Rue, Aravind Sivakumar, Susan M. Lin, Alexander R. Mukhitov, Andrei I. Gritsiuta, Jilly F. Evans, Meghan Kopp, Jeremy Katzen, Annette Robichaud, Elena N. Atochina-Vasserman, Shanru Li, Justine Carl, Apoorva Babu, Michael P. Morley, Edward Cantu, Michael F. Beers, David B. Frank, Edward E. Morrisey, Vera P. Krymskaya
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
The cellular origins of lymphangioleiomyomatosis (LAM), a rare fatal lung disease, are poorly understood. Here the authors identify a mesenchymal cell hub coordinating the LAM phenotype and develop a LAM mouse model where they investigate the co-oper
Externí odkaz:
https://doaj.org/article/920f2bde4ce048d5a6bf73943fc2fe6e
Autor:
Alessandro Venosa, Sophie Cowman, Jeremy Katzen, Yaniv Tomer, Brittnie S. Armstrong, Surafel Mulugeta, Michael F. Beers
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Acute inflammatory exacerbations (AIE) represent precipitous deteriorations of a number of chronic lung conditions, including pulmonary fibrosis (PF), chronic obstructive pulmonary disease and asthma. AIEs are marked by diffuse and persistent polycel
Externí odkaz:
https://doaj.org/article/d1bceeb9ee854c818092784037d79c1d
Autor:
Luis Rodriguez, Yaniv Tomer, Paige Carson, Thalia Dimopoulos, Ming Zhao, Katrina Chavez, Swati Iyer, Li Huang, Christina Ebert, Larisa Sereda, Aditi Murthy, Glenda Trujillo, Michael F. Beers, Jeremy Katzen
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 68:358-365
Autor:
Luis Rodriguez, Swati Iyer, Katrina Chavez, Thalia Dimopoulos, Aditi Murthy, Jeremy Katzen, Surafel Mulugeta, Michael Beers
Publikováno v:
Physiology. 38
Alveolar Type II (AT2) epithelial cell dysfunction is a hallmark of the pathogenesis of Idiopathic Pulmonary Fibrosis (IPF), a progressive interstitial lung disease. Mutations in the surfactant protein C (SP-C) gene (SFTPC) are a high effect size eti
Autor:
Jeremy Katzen, Luis Rodriguez, Yaniv Tomer, Apoorva Babu, Ming Zhao, Aditi Murthy, Paige Carson, Matthew Barrett, Maria C. Basil, Justine Carl, John P. Leach, Michael Morley, Matthew D. McGraw, Surafel Mulugeta, Timothy Pelura, Glenn Rosen, Edward E. Morrisey, Michael F. Beers
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(43)
Disruption of alveolar type 2 cell (AEC2) protein quality control has been implicated in chronic lung diseases, including pulmonary fibrosis (PF). We previously reported the in vivo modeling of a clinical surfactant protein C (SP-C) mutation that led
Autor:
Luis, Rodriguez, Yaniv, Tomer, Paige, Carson, Thalia, Dimopoulos, Ming, Zhao, Katrina, Chavez, Swati, Iyer, Li, Huang, Christina, Ebert, Larisa, Sereda, Aditi, Murthy, Glenda, Trujillo, Michael F, Beers, Jeremy, Katzen
Publikováno v:
American journal of respiratory cell and molecular biology.
Idiopathic Pulmonary Fibrosis (IPF) is a chronic progressive fibrotic interstitial lung disease (ILD). A barrier to developing more effective therapies for IPF is the dearth of preclinical models that recapitulate the early pathobiology of this disea
Autor:
Kathryn Friedman Flack, Jeremy Katzen
Publikováno v:
Chest. 163:744-745
Autor:
Kazushige Shiraishi, Parisha P. Shah, Michael P. Morley, Claudia Loebel, Garrett T. Santini, Jeremy Katzen, Maria C. Basil, Susan M. Lin, Joseph D. Planer, Edward Cantu, Dakota L. Jones, Ana N. Nottingham, Shanru Li, Fabian L. Cardenas-Diaz, Su Zhou, Jason A. Burdick, Rajan Jain, Edward E. Morrisey
Publikováno v:
Cell. 186:1478-1492.e15