Výsledky vyhledávání - "Jeremy J Wolff"

Akademický článek

SITE-SPECIFIC LABELING OF A PROTEIN LYSINE RESIDUE BY NOVEL KINETIC LABELING COMBINATORIAL LIBRARIES

Autor: Allen Krantz, Arthur M Hanel, Ivona Strug, Andrzej Wilczynski, Jeremy J Wolff, Wolin Huang, Linda H Huang, Tina Settineri, Darren L Holmes, Margaret C Hardy, Dominique P Bridon

Publikováno v: Computational and Structural Biotechnology Journal, Vol 9, Iss 15 (2014)

The first example of a kinetic labeling library designed to enable the discovery of affinity labels is presented. Each library component (1) consists of a variable peptidyl component linked to a biotinyl moiety by a 4-mercaptobenzoyl linker in thioes

Externí odkaz: https://doaj.org/article/b5781b56027b45358e4cbb98b9eca02e

Zobrazit plný text záznamu

Akademický článek

Cholesterol-binding translocator protein TSPO regulates steatosis and bile acid synthesis in nonalcoholic fatty liver disease

Publikováno v: iScience, Vol 24, Iss 5, Pp 102457- (2021)

Summary: Translocator protein (TSPO, 18 kDa) levels increase in parallel with the evolution of simple steatosis (SS) to nonalcoholic steatohepatitis (NASH) in nonalcoholic fatty liver disease (NAFLD). However, TSPO function in SS and NASH is unknown.

Externí odkaz: https://doaj.org/article/d8dec988be0e41ee9ce7256bef9886c1

Zobrazit plný text záznamu

High Mass Analysis with a Fourier Transform Ion Cyclotron Resonance Mass Spectrometer: From Inorganic Salt Clusters to Antibody Conjugates and Beyond

Autor: Jeremy J. Wolff, Joseph A. Loo, Piriya Wongkongkathep, Iain Campuzano, Huilin Li, Michael Nshanian, Chawita Netirojjanakul, Carter Lantz, Chris Spahr

Publikováno v: J Am Soc Mass Spectrom
Journal of the American Society for Mass Spectrometry, vol 31, iss 5

Analysis of proteins and complexes under native mass spectrometric (MS) and solution conditions was typically performed using the time-of-flight analyzers, due to their routine high m/z transmission and detection capabilities. However, over recent ye

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87e9e889b3f169a9dc6221a849864816
https://doi.org/10.1021/jasms.0c00030

Zobrazit plný text záznamu

Large-scale interlaboratory DI-FT-ICR MS comparability study employing various systems

Publikováno v: J. Am. Soc. Mass Spectrom. 33, 2203–2214 (2022)
Journal of The American Society for Mass Spectrometry, 33(12), 2203-2214. AMER CHEMICAL SOC
Journal of The American Society for Mass Spectrometry
Journal of The American Society for Mass Spectrometry, 2022, 33 (12), pp.2203-2214. ⟨10.1021/jasms.2c00082⟩

International audience; Ultrahigh resolution mass spectrometry (UHR-MS) coupled with direct infusion (DI) electrospray ionization offers a fast solution for accurate untargeted profiling. Fourier transform ion cyclotron resonance (FT-ICR) mass spectr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d6a8f864314d5f2f165ea13bb494dd
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=66674

Zobrazit plný text záznamu

Spatially resolved isotope tracing reveals tissue metabolic activity

Autor: Lin, Wang, Xi, Xing, Xianfeng, Zeng, S RaElle, Jackson, Tara, TeSlaa, Osama, Al-Dalahmah, Laith Z, Samarah, Katharine, Goodwin, Lifeng, Yang, Melanie R, McReynolds, Xiaoxuan, Li, Jeremy J, Wolff, Joshua D, Rabinowitz, Shawn M, Davidson

Publikováno v: Nature methods. 19(2)

Isotope tracing has helped to determine the metabolic activities of organs. Methods to probe metabolic heterogeneity within organs are less developed. We couple stable-isotope-labeled nutrient infusion to matrix-assisted laser desorption ionization i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4f6535a72b1df877ddf536d9119a03f9
https://pubmed.ncbi.nlm.nih.gov/35132243

Zobrazit plný text záznamu

The Cholesterol-Binding Translocator Protein (18 kDa) Regulates Hepatic Steatosis and Bile Acid Synthesis in Non-Alcoholic Fatty Liver Disease

Autor: Tiffany Huang, Jinjiang Fan, Martine Culty, Bangyan L. Stiles, Peter Metrakos, Hanguy Wu, Chantal M. Sottas, Anthoula Lazaris, Liting Chen, Garett Cheung, Vassilios Papadopoulos, Lu Li, Christina Silvescu, Kinji Asahina, Jeremy J. Wolff, Stephanie Petrillo, Samuel Garza, Yuchang Li

Publikováno v: SSRN Electronic Journal.

Translocator protein (TSPO, 18kDa) levels increase in parallel with the evolution of simple steatosis (SS) to nonalcoholic steatohepatitis (NASH) in non-alcoholic fatty liver disease (NAFLD). However, TSPO function in SS and NASH is unknown. Loss of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::56425bee06cbc73dd80c20f575d543e9
https://doi.org/10.2139/ssrn.3751757

Zobrazit plný text záznamu

Using Tumor Explants for Imaging Mass Spectrometry Visualization of Unlabeled Peptides and Small Molecules

Autor: Jonna Frasor, Jeremy J. Wolff, Brian P. David, Thomas E. Speltz, Laura M. Sanchez, Terry W. Moore, Oleksii Dubrovskyi

Publikováno v: ACS medicinal chemistry letters, vol 9, iss 7

[Image: see text] Matrix assisted laser desorption ionization time-of-flight (MALDI-TOF) imaging mass spectrometry has emerged as a powerful, label-free technique to visualize penetration of small molecules in vivo and in vitro, including in 3D cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a3ed6893e94491d8c42fa0ec785a1c0
https://doi.org/10.1021/acsmedchemlett.8b00091

Zobrazit plný text záznamu

Best practices and benchmarks for intact protein analysis for top-down mass spectrometry

Publikováno v: Nature methods, vol 16, iss 7
Nature Methods
Nature Methods, Nature Publishing Group, 2019, 16 (7), pp.587-594. ⟨10.1038/s41592-019-0457-0⟩
Nature Methods, 2019, 16 (7), pp.587-594. ⟨10.1038/s41592-019-0457-0⟩

One gene can give rise to many functionally distinct proteoforms, each of which has a characteristic molecular mass. Top-down mass spectrometry enables the analysis of intact proteins and proteoforms. Here members of the Consortium for Top-Down Prote

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f4d2ff753f4535711f739a1916ff31f
https://escholarship.org/uc/item/72c7s81j

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání