Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Jeremy J Barr"'
Autor:
Adam Jaffe, Dominic A Fitzgerald, Hiran Selvadurai, Jonathan Iredell, Sharon Hunt, Jagdev Singh, Jeremy J Barr
Publikováno v:
BMJ Open Respiratory Research, Vol 10, Iss 1 (2023)
Introduction Cystic fibrosis (CF) is a multisystem condition that is complicated by recurrent pulmonary infections requiring aggressive antibiotic treatment. This predisposes the patient to complications such as sensorineural hearing loss, renal impa
Externí odkaz:
https://doaj.org/article/5d98a77cb89b44c787c0567222311385
Autor:
Marion C Bichet, Jack Adderley, Laura Avellaneda-Franco, Isabelle Magnin-Bougma, Natasha Torriero-Smith, Linden J Gearing, Celine Deffrasnes, Cassandra David, Genevieve Pepin, Michael P Gantier, Ruby Cy Lin, Ruzeen Patwa, Gregory W Moseley, Christian Doerig, Jeremy J Barr
Publikováno v:
PLoS Biology, Vol 21, Iss 10, p e3002341 (2023)
There is a growing appreciation that the direct interaction between bacteriophages and the mammalian host can facilitate diverse and unexplored symbioses. Yet the impact these bacteriophages may have on mammalian cellular and immunological processes
Externí odkaz:
https://doaj.org/article/6f17943a39654ebdb9c37c01b6a2076b
Publikováno v:
The Lancet Microbe, Vol 3, Iss 3, Pp e160-e161 (2022)
Externí odkaz:
https://doaj.org/article/6146a830d0bd4ccc9cac194f3e370c3c
Autor:
Mohammad Adnan Tariq, Francesca Louise Claire Everest, Lauren eCowley, Anthony eDe Soyza, Giles Samuel Holt, Simon Harwood Bridge, Audrey ePerry, John D Perry, Stephen eBourke, Stephen eCummings, Clare Veronica Lanyon, Jeremy J Barr, Darren Lee Smith
Publikováno v:
Frontiers in Microbiology, Vol 6 (2015)
Pseudomonas aeruginosa (Pa), normally a soil commensal, is an important opportunistic pathogen in Cystic Fibrosis (CF) and non-Cystic Fibrosis Bronchiectasis (nCFBR). Persistent infection correlates with accelerated decline in lung function and early
Externí odkaz:
https://doaj.org/article/8170c93fdc9b41989bd93cda466c5439
Autor:
Marion C. Bichet, Jack Adderley, Laura Avellaneda, Linden J. Gearing, Celine Deffrasnes, Cassandra David, Genevieve Pepin, Michael P. Gantier, Ruby CY Lin, Ruzeen Patwa, Gregory W. Moseley, Christian Doerig, Jeremy J. Barr
There is a growing appreciation that the direct interaction between bacteriophages and the mammalian host can facilitate diverse and unexplored symbioses. Yet the impact these bacteriophages may have on mammalian cellular and immunological processes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::704b1d521ceb038a64e62a6ea4afc5d8
https://doi.org/10.1101/2023.03.10.532157
https://doi.org/10.1101/2023.03.10.532157
Autor:
Shane A Landry, Dinesh Subedi, Jeremy J Barr, Martin I MacDonald, Samantha Dix, Donna M Kutey, Darren Mansfield, Garun S Hamilton, Bradley A Edwards, Simon A Joosten
Publikováno v:
The Journal of Infectious Diseases. 226:199-207
BackgroundHealthcare workers (HCWs) are at risk from aerosol transmission of severe acute respiratory syndrome coronavirus 2. The aims of this study were to (1) quantify the protection provided by masks (surgical, fit-testFAILED N95, fit-testPASSED N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52d7e112ceb1596017f89a9d2d977850
https://doi.org/10.1093/infdis/jiac195
https://doi.org/10.1093/infdis/jiac195
Autor:
Mei-Ling Han, Sue C. Nang, Yu-Wei Lin, Yan Zhu, Heidi H. Yu, Hasini Wickremasinghe, Christopher K. Barlow, Darren J. Creek, Simon Crawford, Gauri Rao, Chongshan Dai, Jeremy J. Barr, Kim Chan, Robert Turner Schooley, Tony Velkov, Jian Li
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 20, Iss, Pp 485-495 (2022)
Computational and Structural Biotechnology Journal, Vol 20, Iss, Pp 485-495 (2022)
Graphical abstract
Resistance to the last-line polymyxins is emerging in multidrug-resistant Klebsiella pneumoniae and phage therapy is a promising alternative. However, phage monotherapy often rapidly causes resistance and few studies have exam
Resistance to the last-line polymyxins is emerging in multidrug-resistant Klebsiella pneumoniae and phage therapy is a promising alternative. However, phage monotherapy often rapidly causes resistance and few studies have exam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6acac77101f62fa1866db98cd3b6e10
https://doi.org/10.1016/j.csbj.2021.12.039
https://doi.org/10.1016/j.csbj.2021.12.039
Autor:
Sue C. Nang, Jing Lu, Heidi H. Yu, Hasini Wickremasinghe, Mohammad A. K. Azad, Meiling Han, Jinxin Zhao, Gauri Rao, Phillip J. Bergen, Tony Velkov, Norelle Sherry, David T. McCarthy, Saima Aslam, Robert T. Schooley, Benjamin P. Howden, Jeremy J. Barr, Yan Zhu, Jian Li
Phage therapy is a promising alternative treatment for multidrug-resistant bacterial infections. Unfortunately, phage resistance represents a major barrier hindering the clinical utility. Mechanistic insights into bacterial phage defense mechanisms a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::665a18723337dce6ac406c39f73b45db
https://doi.org/10.1101/2022.11.14.516531
https://doi.org/10.1101/2022.11.14.516531
Autor:
Wai Hoe Chin, Ciaren Kett, Oren Cooper, Deike Müseler, Yaqi Zhang, Rebecca S. Bamert, Ruzeen Patwa, Laura C. Woods, Citsabehsan Devendran, Denis Korneev, Joe Tiralongo, Trevor Lithgow, Michael J. McDonald, Adrian Neild, Jeremy J. Barr
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(27)
The majority of viruses within the gut are obligate bacterial viruses known as bacteriophages (phages). Their bacteriotropism underscores the study of phage ecology in the gut, where they modulate and coevolve with gut bacterial communities. Traditio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d1d3c8ab657515889709bff98d1335f
https://pubmed.ncbi.nlm.nih.gov/35767643
https://pubmed.ncbi.nlm.nih.gov/35767643
Publikováno v:
Current Opinion in Biotechnology. 68:89-95
The concept of (bacterio)phage therapy is simple; target the phage to the bacterial pathogen causing disease. As phages are natural killers of bacteria, one could expect this to be an easy task. However, when it comes to phage therapy within the gut,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ffdc82072b10634478518f2c8c10ed4
https://doi.org/10.1016/j.copbio.2020.09.016
https://doi.org/10.1016/j.copbio.2020.09.016