Zobrazeno 1 - 10
of 189
pro vyhledávání: '"Jeremy Hughes"'
Publikováno v:
Radiology Case Reports, Vol 19, Iss 6, Pp 2168-2182 (2024)
Primary central nervous system post-transplant lymphoproliferative disease (PCNS-PTLD) is a rare subset of post-transplant lymphoproliferative disorder (PTLD) isolated to the CNS without nodal or extra-nodal organ involvement [1,2]. PCNS-PTLD occurs
Externí odkaz:
https://doaj.org/article/a88ad66f2bd143ec9562b197748d6dcb
Autor:
Eoin D. O’Sullivan, Katie J. Mylonas, Rachel Bell, Cyril Carvalho, David P. Baird, Carolynn Cairns, Kevin M. Gallagher, Ross Campbell, Marie Docherty, Alexander Laird, Neil C. Henderson, Tamir Chandra, Kristina Kirschner, Bryan Conway, Gry H. Dihazi, Michael Zeisberg, Jeremy Hughes, Laura Denby, Hassan Dihazi, David A. Ferenbach
Publikováno v:
JCI Insight, Vol 7, Iss 22 (2022)
Progressive fibrosis and maladaptive organ repair result in significant morbidity and millions of premature deaths annually. Senescent cells accumulate with aging and after injury and are implicated in organ fibrosis, but the mechanisms by which sene
Externí odkaz:
https://doaj.org/article/4b3de86c4fb74e508d5ddb5a3c0e0003
Autor:
Hannah Beckwith, Michael Nation, Aisling McMahon, David C Wheeler, Matthew J Bottomley, Neil S Sheerin, Jeremy Hughes, Sharlene Greenwood
Publikováno v:
BMJ Open, Vol 12, Iss 12 (2022)
Objectives To establish barriers and motivators underlying research engagement among early-career practitioners in nephrology across the UK, in order to guide potential interventions to enhance research involvement in renal units.Design Cross-section
Externí odkaz:
https://doaj.org/article/644000dbb14d42f4af9f76bad3e38632
Autor:
Isaac W. Shaw, Eoin D. O'Sullivan, Angela O. Pisco, Gary Borthwick, Kevin M. Gallagher, Bruno Péault, Jeremy Hughes, David A. Ferenbach
Publikováno v:
Stem Cells Translational Medicine, Vol 10, Iss 8, Pp 1232-1248 (2021)
Abstract The renal mesenchyme contains heterogeneous cells, including interstitial fibroblasts and pericytes, with key roles in wound healing. Although healing is impaired in aged kidneys, the effect of age and injury on the mesenchyme remains poorly
Externí odkaz:
https://doaj.org/article/42a9b397f5f6498cbf0976b58102e425
Publikováno v:
Journal of Research in Higher Education, Vol 5, Iss 1, Pp 47-69 (2021)
Chinese international students account for a significant portion of the US higher education system. This impact is amplified by the fact that many of these students are paying higher out-of-state tuition fees, that many universities rely on to meet t
Externí odkaz:
https://doaj.org/article/198eb31113de464697c7e6f9df5a9994
Autor:
Colin Smith, Rustam Al-Shahi Salman, Karina McDade, Edward Christopher, Neshika Samarasekera, James J M Loan, Jamie Rose, Jack Barrington, Jeremy Hughes
Publikováno v:
BMJ Neurology Open, Vol 4, Iss 1 (2022)
Aims Pharmacological activation of the antioxidative transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) improves outcomes in experimental models of intracerebral haemorrhage (ICH). However, the Nrf2 pathway has not been previousl
Externí odkaz:
https://doaj.org/article/3cfe53a053a74e8583f76664a1754f3e
Publikováno v:
Pharmacy, Vol 10, Iss 5, p 128 (2022)
Organizational vitality encompasses organizational mission and identity, organizational purpose and values, and employee engagement, cohesiveness, anxiety, and information sharing. Using the organizational vitality framework consisting of the followi
Externí odkaz:
https://doaj.org/article/cf89582cdf534f1eb463c2d1f44c88af
Autor:
Jose Meseguer-Ripolles, Baltasar Lucendo-Villarin, Carl Tucker, Sofia Ferreira-Gonzalez, Natalie Homer, Yu Wang, Philip J. Starkey Lewis, Enrique M Toledo, Esther Mellado-Gomez, Joanna Simpson, Oliver Flint, Himjyot Jaiswal, Nicola L. Beer, Allan E. Karlsen, Stuart J. Forbes, James W. Dear, Jeremy Hughes, David C. Hay
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102552- (2021)
Summary: Liver disease is a major cause of premature death. Oxidative stress in the liver represents a key disease driver. Compounds, such as dimethyl fumarate (DMF), can activate the antioxidant response and are used clinically to treat disease. In
Externí odkaz:
https://doaj.org/article/0fd0f2e5fb724e438758d7df1a29d1bc
Autor:
Xiaozhong Zheng, Ailiang Zhang, Margaret Binnie, Kris McGuire, Scott P. Webster, Jeremy Hughes, Sarah E. M. Howie, Damian J. Mole
Publikováno v:
Experimental and Molecular Medicine, Vol 51, Iss 2, Pp 1-14 (2019)
Kidney disease: drug target for acute injury following reperfusion Inhibition of a metabolic enzyme linked to inflammation could be a novel treatment approach for sudden kidney failure following a “reperfusion” injury caused by blood flow returni
Externí odkaz:
https://doaj.org/article/ecd0d27bbf6d459ca7a317a69807af0d
Autor:
Katie L. Connor, Oliver Teenan, Carolynn Cairns, Victoria Banwell, Rachel A.B. Thomas, Julie Rodor, Sarah Finnie, Riinu Pius, Gillian M. Tannahill, Vishal Sahni, Caroline O.S. Savage, Jeremy Hughes, Ewen M. Harrison, Robert B. Henderson, Lorna P. Marson, Bryan R. Conway, Stephen J. Wigmore, Laura Denby
Publikováno v:
JCI Insight, Vol 5, Iss 24 (2020)
Small noncoding RNAs, miRNAs (miRNAs), are emerging as important modulators in the pathogenesis of kidney disease, with potential as biomarkers of kidney disease onset, progression, or therapeutic efficacy. Bulk tissue small RNA-sequencing (sRNA-Seq)
Externí odkaz:
https://doaj.org/article/0e57397672654b13af1fc22e1d4a45d8