Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Jeremy Herrera"'
Autor:
Libang Yang, Adam Gilbertsen, Hong Xia, Alexey Benyumov, Karen Smith, Jeremy Herrera, Emil Racila, Peter B. Bitterman, Craig A. Henke
Publikováno v:
JCI Insight, Vol 8, Iss 4 (2023)
Hypoxia is a sentinel feature of idiopathic pulmonary fibrosis (IPF). The IPF microenvironment contains high lactate levels, and hypoxia enhances cellular lactate production. Lactate, acting through the GPR81 lactate receptor, serves as a signal mole
Externí odkaz:
https://doaj.org/article/3154f58106d74c148d746f3dce91fdab
Autor:
Xiaofei Cong, Nagaraja Nagre, Jeremy Herrera, Andrew C. Pearson, Ian Pepper, Robell Morehouse, Hong-Long Ji, Dianhua Jiang, Rolf D. Hubmayr, Xiaoli Zhao
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-20 (2020)
Abstract Background Chronic tissue injury was shown to induce progressive scarring in fibrotic diseases such as idiopathic pulmonary fibrosis (IPF), while an array of repair/regeneration and stress responses come to equilibrium to determine the outco
Externí odkaz:
https://doaj.org/article/f527195e24d742fa9d88e4d6c987bcee
Autor:
Vitaly A. Polunovsky, Peter B. Bitterman, Douglas Yee, Anja-Katrin Bielinsky, Shunan Li, J. Carlos Manivel, Alexey O. Benyumov, Kathryn L. Schwertfeger, Thomas C. Beadnell, Jose R. Gomez-Garcia, Mark Peterson, Karen Smith, Jeremy Herrera, Svetlana Avdulov
Supplementary Fig. S4. Over expressed eIF4E induces luminal subtype tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f0a8911282c8ce6f0d164aedcd071d
https://doi.org/10.1158/0008-5472.22408124
https://doi.org/10.1158/0008-5472.22408124
Autor:
Vitaly A. Polunovsky, Peter B. Bitterman, Douglas Yee, Anja-Katrin Bielinsky, Shunan Li, J. Carlos Manivel, Alexey O. Benyumov, Kathryn L. Schwertfeger, Thomas C. Beadnell, Jose R. Gomez-Garcia, Mark Peterson, Karen Smith, Jeremy Herrera, Svetlana Avdulov
Supplementary Fig. S3. Double K8/Ki-67staining of wild type (WT) and transgenic (WAP-4E) mammary glands (gestation 6).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c11a70c02ba4631c2dde13518895a499
https://doi.org/10.1158/0008-5472.22408112.v1
https://doi.org/10.1158/0008-5472.22408112.v1
Autor:
Vitaly A. Polunovsky, Peter B. Bitterman, Douglas Yee, Anja-Katrin Bielinsky, Shunan Li, J. Carlos Manivel, Alexey O. Benyumov, Kathryn L. Schwertfeger, Thomas C. Beadnell, Jose R. Gomez-Garcia, Mark Peterson, Karen Smith, Jeremy Herrera, Svetlana Avdulov
Translation initiation factor eIF4E mediates normal cell proliferation, yet induces tumorigenesis when overexpressed. The mechanisms by which eIF4E directs such distinct biologic outputs remain unknown. We found that mouse mammary morphogenesis durin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28346b9f8ca9f8d867cb9937ff1ee65e
https://doi.org/10.1158/0008-5472.c.6507467.v1
https://doi.org/10.1158/0008-5472.c.6507467.v1
Autor:
Vitaly A. Polunovsky, Peter B. Bitterman, Douglas Yee, Anja-Katrin Bielinsky, Shunan Li, J. Carlos Manivel, Alexey O. Benyumov, Kathryn L. Schwertfeger, Thomas C. Beadnell, Jose R. Gomez-Garcia, Mark Peterson, Karen Smith, Jeremy Herrera, Svetlana Avdulov
Supplementary Methods, Figure Legends from eIF4E Threshold Levels Differ in Governing Normal and Neoplastic Expansion of Mammary Stem and Luminal Progenitor Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d867a683acd4aafa4a49f78cade969e
https://doi.org/10.1158/0008-5472.22408109.v1
https://doi.org/10.1158/0008-5472.22408109.v1
Autor:
Vitaly A. Polunovsky, Peter B. Bitterman, Douglas Yee, Anja-Katrin Bielinsky, Shunan Li, J. Carlos Manivel, Alexey O. Benyumov, Kathryn L. Schwertfeger, Thomas C. Beadnell, Jose R. Gomez-Garcia, Mark Peterson, Karen Smith, Jeremy Herrera, Svetlana Avdulov
Supplementary Fig. S5. HA-eIF4E rescues HMEC/hTERT cells from Ras-induced senescence and activates ATR signaling.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d783734c01491ffc1b4c8eeba56f999
https://doi.org/10.1158/0008-5472.22408121
https://doi.org/10.1158/0008-5472.22408121
Autor:
Hong Xia, Alexey Benyumov, Craig A. Henke, Peter B. Bitterman, Jeremy Herrera, Libang Yang, Emilian Racila, Karen Smith, Adam J Gilbertsen
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
Despite modest improvement in patient outcomes from recent advances in pharmacotherapy targeting fibrogenic signaling pathways, idiopathic pulmonary fibrosis (IPF) remains a major unsolved clinical problem. One reason for this is that available antif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d61b27e1839ff838c9a5e77a4772b64
https://doi.org/10.1152/ajplung.00456.2020
https://doi.org/10.1152/ajplung.00456.2020
Autor:
M. Angeles Montero, Rajamiyer Venkateswaran, John F. Blaikley, Lewis Dingle, Martin A. Schwartz, Jeremy Herrera, Rajesh Shah, Craig Lawless
BackgroundThe Fibroblastic Focus (FF) is the signature lesion of Idiopathic Pulmonary Fibrosis (IPF) where myofibroblasts accumulate and extracellular matrix (ECM) is produced. However, the molecular composition and function of the FF and surrounding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27df2797d060e3f2c13b639dcec5b054
https://doi.org/10.1101/2021.11.06.467549
https://doi.org/10.1101/2021.11.06.467549
Autor:
Silvia Rosini, Craig Lawless, Judith E. Allen, Alistair L Chenery, Bhk Chan, Tara E. Sutherland, P'ng Loke, Jeremy Herrera, James E Parkinson, Andrew S. MacDonald, Karl E. Kadler
IL-13 plays a key role during protective type 2 immune responses at mucosal sites, such as during infection with nematodes. However, dysregulation of IL-13 can also contribute to the pathogenesis of atopic and fibrotic diseases such as allergic asthm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c08bfcf6e512c069dd75011cf1e5921f
https://doi.org/10.1101/2020.10.14.337949
https://doi.org/10.1101/2020.10.14.337949