Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jeremy Hembrador"'
Autor:
Timothy J. Church, Elad Kaufman, Sabine Axt, R. S. L. Chang, Ngoc Mai, Jacobsen John R, Ross G. Vickery, Shanti M. Amagasu, Courtney Gee, Thomas E. Jenkins, Jeremy Hembrador, J A M Smith
Publikováno v:
Molecular Pharmacology. 69:921-931
The interaction of symmetrical lidocaine dimers with voltage-gated Na+ channels (VGSCs) was examined using a FLIPR membrane potential assay and voltage-clamp. The dimers, in which the tertiary amines of the lidocaine moieties are linked by an alkylen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2a2c445f60db91411e99c7d42b06ae0
https://doi.org/10.1124/mol.105.019257
https://doi.org/10.1124/mol.105.019257
Autor:
N Mai, J A M Smith, R G Vickery, R Chang, J Martin, E Kaufman, D. Marquess, Jeremy Hembrador, S.M. Amagasu, M D O'Keefe, C Gee
Publikováno v:
Receptors and Channels. 10:11-23
A novel, membrane potential sensitive dye and a fluorescence imaging plate reader (FLIPR) have been used to characterize the pharmacological properties of rat Na(v)1.8 voltage-gated sodium channels (VGSC) in parallel with rat Na(v)1.2a and human Na(v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f93f84d9579162e5b274ed7991aed6f
https://doi.org/10.3109/10606820490270410
https://doi.org/10.3109/10606820490270410