Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jeremy Haaf"'
Autor:
Diana Amend, Julia Skokowa, Masoud Nasri, Maksim Klimiankou, Jeremy Haaf, Karl Welte, Regine Bernhard, Benjamin Secker, Malte U Ritter, Perihan Mir, Benjamin Dannenmann, Cornelia Zeidler, Ingeborg Steiert
Publikováno v:
Blood. 136:22-22
Patients with the rare pre-leukemia bone marrow failure syndrome severe congenital neutropenia (CN) have markedly reduced numbers of neutrophils in peripheral blood ( Here, we describe for the first time the application of CRISPR/Cas9 gene-editing in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3f417db3ca3ad4392abd8f34c157075
https://doi.org/10.1182/blood-2020-140260
https://doi.org/10.1182/blood-2020-140260
Autor:
Julia Skokowa, Birte Hernandez Alvarez, Murray Coles, Malte Ritter, Masoud Nasri, Jérémy Haaf, Narges Aghaallaei, Yun Xu, Perihan Mir, Ann-Christin Krahl, Katherine W. Rogers, Kateryna Maksymenko, Baubak Bajoghli, Karl Welte, Andrei N. Lupas, Patrick Müller, Mohammad ElGamacy
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Skokowa et al. reconstruct the fold of a granulopoietic cytokine, resulting in de novo, hyperstable, highly active proteins with therapeutic potential for treating several neutropenia disorders.
Externí odkaz:
https://doaj.org/article/68deee8b6ece4f268cc8599f9cf0df38