Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jeremy Gingrich"'
Publikováno v:
Environment International, Vol 147, Iss , Pp 106301- (2021)
Predictions from physiologically based toxicokinetic (PBTK) models can help inform human health risk assessment for potentially toxic chemicals in the environment. Bisphenol S (BPS) is the second most abundant bisphenol detected in humans in the Unit
Externí odkaz:
https://doaj.org/article/e2690c9422824bff9ca2735d3a92888d
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 2, p 671 (2022)
The placenta supports fetal growth and is vulnerable to exogenous chemical exposures. We have previously demonstrated that exposure to the emerging chemical bisphenol S (BPS) can alter placental endocrine function. Mechanistically, we have demonstrat
Externí odkaz:
https://doaj.org/article/81a6cdb1fa3246b08c1f278d7069e0cd
Autor:
Stefania Marsili, Sem Genini, Raghavi Sudharsan, Jeremy Gingrich, Gustavo D Aguirre, William A Beltran
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0115723 (2015)
PURPOSE:To examine the occurrence of endoplasmic reticulum (ER) stress and the unfolded protein response (UPR) following acute light damage in the naturally-occurring canine model of RHO-adRP (T4R RHO dog). METHODS:The left eyes of T4R RHO dogs were
Externí odkaz:
https://doaj.org/article/7a0c4fb90ce84ad48063873a4d1b5b3a
Publikováno v:
Lab Chip
Placental trophoblast cells invasion into the maternal uterus is an essential and complex event in the formation of the maternal-fetal interface. Commonly used two-dimensional (2D) cell invasion tools do not accurately represent the in vivo cell inva
Publikováno v:
Trends Endocrinol Metab
Endocrine disrupting chemicals (EDCs) are chemicals that can interfere with normal endocrine signals. Human exposure to EDCs is particularly concerning during vulnerable periods of life, such as pregnancy. However, often overlooked is the effect that
Autor:
Jiongjie Jing, Almudena Veiga-Lopez, Carlos Murga-Zamalloa, Denny Martin, Sarah Pearl, Jeremy Gingrich, Yong Pu
Publikováno v:
Arch Toxicol
Tributyltin (TBT), an organotin chemical used as a catalyst and biocide, can stimulate cholesterol efflux in non-steroidogenic cells. Since cholesterol is the first limiting step for sex hormone production, we hypothesized that TBT disrupts intracell
Autor:
Rajendiran Karthikraj, R Ehrhardt, Jeremy Gingrich, Almudena Veiga-Lopez, Kurunthachalam Kannan, Yong Pu
Publikováno v:
Chemosphere. 220:185-194
Bisphenol A (BPA), S (BPS), and F (BPF) are among the most abundant bisphenols detected in humans, yet pregnancy toxicokinetics for BPS or BPF remain unknown. Because gestational BPS can disrupt placental function and result in reproductive and metab
Publikováno v:
Toxicol Mech Methods
Gap junction intercellular communication (GJIC) is a necessary process for placental development. GJIC can be assessed with a parachute assay, where fluorescent dye-loaded donor cells are ‘parachuted’ onto acceptor cells and dye diffuses to adjac
Publikováno v:
Environment International, Vol 147, Iss, Pp 106301-(2021)
Environ Int
Environ Int
Predictions from physiologically based toxicokinetic (PBTK) models can help inform human health risk assessment for potentially toxic chemicals in the environment. Bisphenol S (BPS) is the second most abundant bisphenol detected in humans in the Unit
Publikováno v:
Trends in Endocrinology & Metabolism. 29:607-625
Endocrine disrupting chemicals (EDCs) are compounds that are part of everyday consumer products and industrial manufacturing processes. EDCs can interfere with the endocrine system, including the adipose tissue. Accumulating evidence from epidemiolog