Výsledky vyhledávání - "Jeremy Giltner"

Safety and Pharmacokinetics of Single Doses of (+)-Calanolide A, a Novel, Naturally Occurring Nonnucleoside Reverse Transcriptase Inhibitor, in Healthy, Human Immunodeficiency Virus-Negative Human Subjects

Autor: Dwain T. Tolbert, David A. Eiznhamer, Bipul Dutta, Jon L. Ruckle, Terri Creagh, Jeremy Giltner, Ze-Qi Xu, Michael T. Flavin

Publikováno v: Antimicrobial Agents and Chemotherapy. 45:1379-1386

(+)-Calanolide A is a novel, naturally occurring, nonnucleoside inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase first isolated from a tropical tree (Calophyllum lanigerum) in the Malaysian rain forest. Previous studies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7149811ac1ebf40fd608bb254b4b2ed3
https://doi.org/10.1128/aac.45.5.1379-1386.2001

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Safety and pharmacokinetic profile of multiple escalating doses of (+)-calanolide A, a naturally occurring nonnucleoside reverse transcriptase inhibitor, in healthy HIV-negative volunteers

Autor: Michael T. Flavin, David A. Eiznhamer, Jon L. Ruckle, Bipul Dutta, Tuah R. Jenta, Jeremy Giltner, Dwain T. Tolbert, Ze-Qi Xu, Terri Creagh

Publikováno v: HIV clinical trials. 3(6)

(+)-Calanolide A is a naturally occurring nonnucleoside reverse transciptase inhibitor (NNRTI) that exhibits enhanced activity against HIV-1 isolates with the Y181C mutation and retains activity against HIV-1 isolates with dual Y181C and K103N mutati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaa33b4c2edacb288a7b528f3c8d86a9
https://pubmed.ncbi.nlm.nih.gov/12501127

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