Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Jeremy G. Turner"'
Autor:
Alec N. Salt, Jeremy G. Turner
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionOne of the primary tenets in pharmacotherapy is that the applied drug must reach the target tissue at therapeutic concentration. For many therapies intended to treat hearing disorders it has become apparent that we have failed to achieve
Externí odkaz:
https://doaj.org/article/2119fa32dd4647589ff4f73e54e1c76c
Autor:
Jeremy G. Turner
Publikováno v:
J Am Assoc Lab Anim Sci
Noise and vibration are present in every room of laboratory animal vivaria, with great variability from room-to-room and facility-to-facility. Such stimuli are rarely measured. As a result, the many stakeholders involved in biomedical research, (for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0696071a44f0aff1a34a284feb65cc01
https://doi.org/10.30802/aalas-jaalas-19-000131
https://doi.org/10.30802/aalas-jaalas-19-000131
Autor:
Jeremy G. Turner, Deb L. Larsen
Publikováno v:
Hearing Research. 334:30-36
Fischer Brown Norway (FBN) rats (n = 233) were unilaterally exposed to 12 different combinations of noise intensity, duration, and spectrum, while 46 rats served as sham-exposed controls. Rats were behaviorally tested for tinnitus and hyperacusis usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d2b5b486eb23ea192bb7b37829d91ff
https://doi.org/10.1016/j.heares.2015.11.004
https://doi.org/10.1016/j.heares.2015.11.004
Autor:
Jeremy G. Turner, Daniel A. Llano, Kevin A. Stebbings, A. Ravindra, H. W. Choi, Donald M. Caspary
Publikováno v:
The Journal of Physiology. 594:207-221
Key points Ageing is associated with hearing loss and changes in GABAergic signalling in the auditory system. We tested whether GABAergic signalling in an isolated forebrain preparation also showed ageing-related changes. A novel approach was used, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::349ce875a4def29ca4337702eb5ba121
https://doi.org/10.1113/jp271221
https://doi.org/10.1113/jp271221
Publikováno v:
Journal of Neuroscience. 35:9369-9380
Accumulating evidence suggests a role for inhibitory neurotransmitter dysfunction in the pathology of tinnitus. Opposing hypotheses proposed either a pathologic decrease or increase of GABAergic inhibition in medial geniculate body (MGB). In thalamus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5da275cbd580aea8fa10fed2227f1482
https://doi.org/10.1523/jneurosci.5054-14.2015
https://doi.org/10.1523/jneurosci.5054-14.2015
Autor:
Donald M. Caspary, Jennifer L. Parrish, Loren Zuiderveld, Esma Idrezbegovic, Barbara Canlon, Larry F. Hughes, Jeremy G. Turner, Stacy Darr
Publikováno v:
Ear & Hearing. 34:151-159
Objectives Presbyacusis, one of the most common ailments of the elderly, is often treated with hearing aids, which serve to reintroduce some or all of those sounds lost to peripheral hearing loss. However, little is known about the underlying changes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05616c61beab2702a37218a3bbc08455
https://doi.org/10.1097/aud.0b013e318269ca5b
https://doi.org/10.1097/aud.0b013e318269ca5b
Publikováno v:
Hearing Research. 264:79-85
Presbycusis can be considered a slow age-related peripheral and central deterioration of auditory function which manifests itself as deficits in speech comprehension, especially in noisy environments. The present study examined neural correlates of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4abf4a81718879cf808f93ca97e6bcba
https://doi.org/10.1016/j.heares.2009.09.005
https://doi.org/10.1016/j.heares.2009.09.005
Autor:
Craig Whitworth, Jennifer R. Bunch, Jeremy G. Turner, Debashree Mukherjea, Vickram Ramkumar, Leonard P. Rybak, Sarvesh Jajoo
Publikováno v:
The Journal of Neuroscience. 28:13056-13065
Cisplatin, a chemotherapeutic agent of choice for the treatment of solid tumors, produces hearing loss in approximately half a million new cancer patients annually in the United States. The hearing loss is due, in part, to increased generation of rea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d323f6a26415ca0204296e0f16714a9b
https://doi.org/10.1523/jneurosci.1307-08.2008
https://doi.org/10.1523/jneurosci.1307-08.2008
Publikováno v:
Journal of Experimental Biology. 211:1781-1791
SUMMARY Aging and acoustic trauma may result in partial peripheral deafferentation in the central auditory pathway of the mammalian brain. In accord with homeostatic plasticity, loss of sensory input results in a change in pre- and postsynaptic GABAe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4c16cc3b73ec7882c38b5263eed219d
https://doi.org/10.1242/jeb.013581
https://doi.org/10.1242/jeb.013581
Autor:
Wei Sun, Jeremy G. Turner, Edward Lobarinas, Daniel Stolzberg, Richard Salvi, Liyan Zhang, Guang Yang
Publikováno v:
Hearing Research. 226:244-253
Neurophysiological studies of salicylate-induced tinnitus have generally been carried out under anesthesia, a condition that abolishes the perception of tinnitus and depresses neural activity. To overcome these limitations, measurement of salicylate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7206d7ad1af3d7d4edc669003f9ba7c
https://doi.org/10.1016/j.heares.2006.06.013
https://doi.org/10.1016/j.heares.2006.06.013