Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jeremy G, Koob"'
Publikováno v:
Nature Protocols. 14:2986-3012
Rapid detection of nucleic acids is integral to applications in clinical diagnostics and biotechnology. We have recently established a CRISPR-based diagnostic platform that combines nucleic acid pre-amplification with CRISPR-Cas enzymology for specif
Autor:
Patricia R. Feliciano, Pablo Mesa, Jeremy G. Koob, Guillermo Montoya, Max J. Kellner, Omar O. Abudayyeh, Edward J. Brignole, Stefano Stella, Ian Slaymaker, Soumya Kannan, Jonathan Strecker, Feng Zhang, Jonathan S. Gootenberg
Publikováno v:
Cell Reports, Vol 34, Iss 10, Pp 108865-(2021)
Slaymaker, I M, Mesa, P, Kellner, M J, Kannan, S, Brignole, E, Koob, J, Feliciano, P R, Stella, S, Abudayyeh, O O, Gootenberg, J S, Strecker, J, Montoya, G & Zhang, F 2019, ' High-Resolution Structure of Cas13b and Biochemical Characterization of RNA Targeting and Cleavage ', Cell Reports, vol. 26, no. 13, pp. 3741-3751.e5 . https://doi.org/10.1016/j.celrep.2019.02.094
Cell Reports, Vol 26, Iss 13, Pp 3741-3751.e5 (2019)
Slaymaker, I M, Mesa, P, Kellner, M J, Kannan, S, Brignole, E, Koob, J, Feliciano, P R, Stella, S, Abudayyeh, O O, Gootenberg, J S, Strecker, J, Montoya, G & Zhang, F 2019, ' High-Resolution Structure of Cas13b and Biochemical Characterization of RNA Targeting and Cleavage ', Cell Reports, vol. 26, no. 13, pp. 3741-3751.e5 . https://doi.org/10.1016/j.celrep.2019.02.094
Cell Reports, Vol 26, Iss 13, Pp 3741-3751.e5 (2019)
Summary: Type VI CRISPR-Cas systems contain programmable single-effector RNA-guided RNases, including Cas13b, one of the four known family members. Cas13b, which has been used for both RNA editing and nucleic acid detection, is unique among type VI C
Autor:
Jonathan S. Gootenberg, Brian Franklin, Omar O. Abudayyeh, Julia Joung, Paul Kirchgatterer, Feng Zhang, Alim Ladha, Max J. Kellner, David Benjamin Turitz Cox, Jeremy G. Koob
Publikováno v:
Other repository
Programmable RNA editing enables reversible recoding of RNA information for research and disease treatment. Previously, we developed a programmable adenosine-to-inosine (A-to-I) RNA editing approach by fusing catalytically inactivate RNA-targeting CR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f581ed67aad135107181ff421bdf33ad
https://hdl.handle.net/1721.1/126395
https://hdl.handle.net/1721.1/126395
Publikováno v:
Nature protocols. 14(10)
Rapid detection of nucleic acids is integral to applications in clinical diagnostics and biotechnology. We have recently established a CRISPR-based diagnostic platform that combines nucleic acid pre-amplification with CRISPR-Cas enzymology for specif
Publikováno v:
Nature Protocols. 15:1311-1311
Rapid detection of nucleic acids is integral for applications in clinical diagnostics and biotechnology. We have recently established a CRISPR-based diagnostic platform that combines nucleic acid pre-amplification with CRISPR-Cas enzymology for speci