Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jeremy Florman"'
Autor:
Bruno Hernandez-Cravero, Sofia Gallino, Jeremy Florman, Cecilia Vranych, Philippe Diaz, Ana Belén Elgoyhen, Mark J Alkema, Diego de Mendoza
Publikováno v:
PLoS Genetics, Vol 18, Iss 11, p e1010346 (2022)
The nematode Caenorhabditis elegans requires exogenous cholesterol to survive and its depletion leads to early developmental arrest. Thus, tight regulation of cholesterol storage and distribution within the organism is critical. Previously, we demons
Externí odkaz:
https://doaj.org/article/ffb746efddee491aab419cf91b15ab99
Publikováno v:
eLife, Vol 11 (2022)
In the aging brain, many of the alterations underlying cognitive and behavioral decline remain opaque. Caenorhabditis elegans offers a powerful model for aging research, with a simple, well-studied nervous system to further our understanding of the c
Externí odkaz:
https://doaj.org/article/5ae94756048d4af69029c81cf5b2a695
Autor:
Shankar Ramachandran, Navonil Banerjee, Raja Bhattacharya, Michele L Lemons, Jeremy Florman, Christopher M Lambert, Denis Touroutine, Kellianne Alexander, Liliane Schoofs, Mark J Alkema, Isabel Beets, Michael M Francis
Publikováno v:
eLife, Vol 10 (2021)
Neuromodulators promote adaptive behaviors that are often complex and involve concerted activity changes across circuits that are often not physically connected. It is not well understood how neuromodulatory systems accomplish these tasks. Here, we s
Externí odkaz:
https://doaj.org/article/19100ae39dc84f1fa80aeca26480415c
Autor:
Yuan Wang, Xiaoqian Zhang, Qi Xin, Wesley Hung, Jeremy Florman, Jing Huo, Tianqi Xu, Yu Xie, Mark J Alkema, Mei Zhen, Quan Wen
Publikováno v:
eLife, Vol 9 (2020)
Complex animal behaviors arise from a flexible combination of stereotyped motor primitives. Here we use the escape responses of the nematode Caenorhabditis elegans to study how a nervous system dynamically explores the action space. The initiation of
Externí odkaz:
https://doaj.org/article/369ed084df134017b4663dd145e32306
Autor:
Alison Philbrook, Shankar Ramachandran, Christopher M Lambert, Devyn Oliver, Jeremy Florman, Mark J Alkema, Michele Lemons, Michael M Francis
Publikováno v:
eLife, Vol 7 (2018)
In neural circuits, individual neurons often make projections onto multiple postsynaptic partners. Here, we investigate molecular mechanisms by which these divergent connections are generated, using dyadic synapses in C. elegans as a model. We report
Externí odkaz:
https://doaj.org/article/896461029c4a4bc2a481350b9d911865
Autor:
Jeremy Florman, Mark Alkema
Publikováno v:
PLoS genetics. 18(3)
Co-localization and co-transmission of neurotransmitters and neuropeptides is a core property of neural signaling across species. While co-transmission can increase the flexibility of cellular communication, understanding the functional impact on neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd488a0bdee71bced193d10376f7dcc5
https://pubmed.ncbi.nlm.nih.gov/35239681
https://pubmed.ncbi.nlm.nih.gov/35239681
Age-associated changes to neuronal dynamics involve a disruption of excitatory/inhibitory balance in
Publikováno v:
eLife. 11
In the aging brain, many of the alterations underlying cognitive and behavioral decline remain opaque. C. elegans offers a powerful model for aging research, with a simple, well-studied nervous system to further our understanding of the cellular modi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be9564304bc4164442c6c385e7eef885
https://pubmed.ncbi.nlm.nih.gov/35703498
https://pubmed.ncbi.nlm.nih.gov/35703498
Autor:
Liliane Schoofs, Isabel Beets, Denis Touroutine, Christopher M. Lambert, Kellianne Alexander, Navonil Banerjee, Shankar Ramachandran, Jeremy Florman, Raja Bhattacharya, Michael M. Francis, Mark J. Alkema, Michele L. Lemons
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
SUMMARYNeuromodulators promote adaptive behaviors that are often complex and involve concerted activity changes across circuits that are often not physically connected. It is not well understood how neuromodulatory systems accomplish these tasks. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9ab0db0314cec214bdc9918500150bc
https://pubmed.ncbi.nlm.nih.gov/34766905
https://pubmed.ncbi.nlm.nih.gov/34766905
Autor:
Jing Huo, Qi Xin, Wesley Hung, Yu Xie, Mark J. Alkema, Yuan Wang, Quan Wen, Tianqi Xu, Mei Zhen, Jeremy Florman, Xiaoqian Zhang
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Complex animal behaviors arise from a flexible combination of stereotyped motor primitives. Here we use the escape responses of the nematode Caenorhabditis elegans to study how a nervous system dynamically explores the action space. The initiation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a741c9380731dfa0992cd99600798466
https://doi.org/10.7554/elife.56942
https://doi.org/10.7554/elife.56942