Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Jeremy F Reiter"'
Autor:
Emma A Hall, Dhivya Kumar, Suzanna L Prosser, Patricia L Yeyati, Vicente Herranz-Pérez, Jose Manuel García-Verdugo, Lorraine Rose, Lisa McKie, Daniel O Dodd, Peter A Tennant, Roly Megaw, Laura C Murphy, Marisa F Ferreira, Graeme Grimes, Lucy Williams, Tooba Quidwai, Laurence Pelletier, Jeremy F Reiter, Pleasantine Mill
Publikováno v:
eLife, Vol 12 (2023)
Centrosomes are orbited by centriolar satellites, dynamic multiprotein assemblies nucleated by Pericentriolar material 1 (PCM1). To study the requirement for centriolar satellites, we generated mice lacking PCM1, a crucial component of satellites. Pc
Externí odkaz:
https://doaj.org/article/04eeb1d5dd2f432185301e466a6cac04
Autor:
Shaun R Abrams, Jeremy F Reiter
Publikováno v:
eLife, Vol 10 (2021)
Craniofacial defects are among the most common phenotypes caused by ciliopathies, yet the developmental and molecular etiology of these defects is poorly understood. We investigated multiple mouse models of human ciliopathies (including Tctn2, Cc2d2a
Externí odkaz:
https://doaj.org/article/f11836e51aab41898f41c1a9efe6035c
Autor:
Kerstin Hasenpusch-Theil, Christine Laclef, Matt Colligan, Eamon Fitzgerald, Katherine Howe, Emily Carroll, Shaun R Abrams, Jeremy F Reiter, Sylvie Schneider-Maunoury, Thomas Theil
Publikováno v:
eLife, Vol 9 (2020)
During the development of the cerebral cortex, neurons are generated directly from radial glial cells or indirectly via basal progenitors. The balance between these division modes determines the number and types of neurons formed in the cortex thereb
Externí odkaz:
https://doaj.org/article/4ec1b1854e624433b874c7c5f09a5255
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0212735 (2019)
Due to low labeling efficiency and structural heterogeneity in fluorescence-based single-molecule localization microscopy (SMLM), image alignment and quantitative analysis is often required to make accurate conclusions on the spatial relationships be
Externí odkaz:
https://doaj.org/article/f94a1bb1f58b4077bd8b5a96792d333c
Autor:
Kodaji Ha, Nadine Mundt-Machado, Paola Bisignano, Aide Pinedo, David R. Raleigh, Gabriel Loeb, Jeremy F. Reiter, Erhu Cao, Markus Delling
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Polycystin-1 (PC-1) and PC-2 form a heteromeric ion channel complex that is abundantly expressed in primary cilia of renal epithelial cells. This complex functions as a non-selective cation channel, and mutations within the polycystin comple
Externí odkaz:
https://doaj.org/article/4f410fb7903d42e79269e3247aa712f3
Autor:
Chunmei Li, Victor L Jensen, Kwangjin Park, Julie Kennedy, Francesc R Garcia-Gonzalo, Marta Romani, Roberta De Mori, Ange-Line Bruel, Dominique Gaillard, Bérénice Doray, Estelle Lopez, Jean-Baptiste Rivière, Laurence Faivre, Christel Thauvin-Robinet, Jeremy F Reiter, Oliver E Blacque, Enza Maria Valente, Michel R Leroux
Publikováno v:
PLoS Biology, Vol 14, Iss 3, p e1002416 (2016)
Cilia have a unique diffusion barrier ("gate") within their proximal region, termed transition zone (TZ), that compartmentalises signalling proteins within the organelle. The TZ is known to harbour two functional modules/complexes (Meckel syndrome [M
Externí odkaz:
https://doaj.org/article/8218a5f05b2d4ec7ac530fd44daeffc4
Autor:
Laura E Yee, Francesc R Garcia-Gonzalo, Rachel V Bowie, Chunmei Li, Julie K Kennedy, Kaveh Ashrafi, Oliver E Blacque, Michel R Leroux, Jeremy F Reiter
Publikováno v:
PLoS Genetics, Vol 11, Iss 11, p e1005627 (2015)
Mutations in genes encoding cilia proteins cause human ciliopathies, diverse disorders affecting many tissues. Individual genes can be linked to ciliopathies with dramatically different phenotypes, suggesting that genetic modifiers may participate in
Externí odkaz:
https://doaj.org/article/f350bad5591849009c0460aaad0857a5
Autor:
Andrew Kodani, Timothy W Yu, Jeffrey R Johnson, Divya Jayaraman, Tasha L Johnson, Lihadh Al-Gazali, Lāszló Sztriha, Jennifer N Partlow, Hanjun Kim, Alexis L Krup, Alexander Dammermann, Nevan J Krogan, Christopher A Walsh, Jeremy F Reiter
Publikováno v:
eLife, Vol 4 (2015)
Primary microcephaly (MCPH) associated proteins CDK5RAP2, CEP152, WDR62 and CEP63 colocalize at the centrosome. We found that they interact to promote centriole duplication and form a hierarchy in which each is required to localize another to the cen
Externí odkaz:
https://doaj.org/article/b40640f1f0e84ee9a3c58b1340bbe175
Autor:
Julie Hunkapiller, Yin Shen, Aaron Diaz, Gerard Cagney, David McCleary, Miguel Ramalho-Santos, Nevan Krogan, Bing Ren, Jun S Song, Jeremy F Reiter
Publikováno v:
PLoS Genetics, Vol 8, Iss 3, p e1002576 (2012)
Polycomb repressive complex 2 (PRC2) trimethylates lysine 27 of histone H3 (H3K27me3) to regulate gene expression during diverse biological transitions in development, embryonic stem cell (ESC) differentiation, and cancer. Here, we show that Polycomb
Externí odkaz:
https://doaj.org/article/98757e8406d4491a99381d58e6311d59
PDF file - 77K, Src activity in SmoM2 induced skin neoplasia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ace0ccb1ff20017919400be0c23d0093
https://doi.org/10.1158/0008-5472.22400307
https://doi.org/10.1158/0008-5472.22400307
