Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Jeremy D. Pearson"'
Autor:
Jeremy D. Pearson, Justin C Mason
Publikováno v:
Free radical biologymedicine. 125
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b88adebdaa4a2289e61a22cc5e16aab5
https://pubmed.ncbi.nlm.nih.gov/30217269
https://pubmed.ncbi.nlm.nih.gov/30217269
Publikováno v:
Cardiovascular research. 114(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e16b303c0c474de46a1b1300be1b63cb
https://pubmed.ncbi.nlm.nih.gov/29481651
https://pubmed.ncbi.nlm.nih.gov/29481651
Scientists on the Spot: The past, present, and future of the Council on Basic Cardiovascular Science
Publikováno v:
Cardiovascular Research. 114:e74-e75
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01a1bb953a79759950b9a91c042a8124
https://doi.org/10.1093/cvr/cvy178
https://doi.org/10.1093/cvr/cvy178
Autor:
Carol M. Black, Christopher P. Denton, Roland M. du Bois, Alan M. Holmes, Jeremy D. Pearson, David Abraham, George Bou-Gharios, Elisabetta A. Renzoni, Michael R. Dashwood, Xu Shiwen, Sarah L. Howat, Andrew Leask
The endothelins are a family of endothelium-derived peptides that possess a variety of biological activities, including potent vasoconstriction. Endothelin-1 (ET-1) is up-regulated during tissue repair and pulmonary fibrosis. Here, we use genome-wide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b00d73c1d78ddca5fd4861c6c3f1698e
https://ora.ox.ac.uk/objects/uuid:2e338bb4-0180-412e-88f3-09dea7cd7aaf
https://ora.ox.ac.uk/objects/uuid:2e338bb4-0180-412e-88f3-09dea7cd7aaf
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 298:H1850-H1856
Endothelial properties are affected by mechanical stresses. Several studies have shown that an acute application of shear stress increases the permeability of endothelial monolayers in culture. We investigated whether more prolonged application of sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::081e540dd98f7cfbd8f4d3901d08368b
https://doi.org/10.1152/ajpheart.00114.2010
https://doi.org/10.1152/ajpheart.00114.2010
Autor:
Jeremy D. Pearson
Publikováno v:
Cardiovascular research. 108(3)
This editorial refers to ‘Endothelial-to-mesenchymal transition contributes to fibro-proliferative vascular disease and is modulated by fluid shear stress’ by J.-R. Moonen et al. , doi:10.1093/cvr/cvv175. In most healthy blood vessels, average en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7a82819adc317b1ceffa7977683e293
https://pubmed.ncbi.nlm.nih.gov/26084310
https://pubmed.ncbi.nlm.nih.gov/26084310
Autor:
Jeremy D. Pearson
Publikováno v:
Interaction of Cells with Natural and Foreign Surfaces ISBN: 9781461293071
Vascular endothelial cells form a monolayer that, except at a few specialised sites, continuously lines blood vessels and constitutes the primary interface between the bloodstream and all extravascular tissue.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66703def1f0cbf6a34e8750b88577dac
https://doi.org/10.1159/000414546
https://doi.org/10.1159/000414546
Autor:
Susan D. Brain, KA Brown, David F. Treacher, Jeremy D. Pearson, Jonathan D. Edgeworth, SM Lewis
Publikováno v:
The Lancet. 368:157-169
Multiple organ failure is a major threat to the survival of patients with sepsis and systemic inflammation. In the UK and in the USA, mortality rates are currently comparable with and projected to exceed those from myocardial infarction. The immune s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcdc9505f80a60fdb8d0cea35a900366
https://doi.org/10.1016/s0140-6736(06)69005-3
https://doi.org/10.1016/s0140-6736(06)69005-3
Autor:
Daphne Pala, Carol M. Black, David E. Carter, Lee Anne Stanton, Xu Shiwen, Richard Stratton, Sarah L. Howat, Karen M. Lyons, George Bou-Gharios, Elisabetta A. Renzoni, Frank Beier, Laura Kennedy, Yunliang Chen, David Abraham, Jeremy D. Pearson, Andrew Leask
Publikováno v:
Journal of Biological Chemistry. 281:10715-10726
CCN2 is induced by transforming growth factor-beta (TGFbeta) in fibroblasts and is overexpressed in connective tissue disease. CCN2 has been proposed to be a downstream mediator of TGFbeta action in fibroblasts; however, the role of CCN2 in regulatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::186b07baf7c92f5f090123578c36516a
https://doi.org/10.1074/jbc.m511343200
https://doi.org/10.1074/jbc.m511343200
Publikováno v:
Arthritis & Rheumatism. 54:649-660
Endothelin 1 (ET-1) has been implicated in the pathogenesis of fibrotic and inflammatory diseases, including scleroderma. In addition to modulating vascular tone and extracellular matrix turnover, ET-1 up-regulates cell surface adhesion molecules inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f4a0bceac46ac5a8b7e8089f2829556
https://doi.org/10.1002/art.21572
https://doi.org/10.1002/art.21572