Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jeremy D Rhodes"'
Autor:
Andrew Osborne, Amal Aldarwesh, Jeremy D Rhodes, David C Broadway, Claire Everitt, Julie Sanderson
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0115591 (2015)
PURPOSE:Elevated intraocular pressure (IOP) is a major risk factor for glaucoma. One consequence of raised IOP is that ocular tissues are subjected to increased hydrostatic pressure (HP). The effect of raised HP on stress pathway signaling and retina
Externí odkaz:
https://doaj.org/article/16c9574f65c14bccac1c6c157c806ef6
Publikováno v:
Experimental Eye Research. 89:995-1002
Quercetin is a dietary bioflavonoid which has been shown to inhibit lens opacification in a number of models of cataract. The objectives of this study were to determine gene expression changes in human lens epithelial cells in response to quercetin a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52091a4037df36ae70fb9a08be749f17
https://doi.org/10.1016/j.exer.2009.08.011
https://doi.org/10.1016/j.exer.2009.08.011
Autor:
Jeremy D. Rhodes, Julie Sanderson
Publikováno v:
Experimental Eye Research. 88:226-234
Excessive Ca(2+) can be detrimental to cells and raised levels of Ca(2+) in human lenses with cortical cataract have been found to play a major role in the opacification process. Ca(2+) homeostasis is therefore, recognised as having fundamental impor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61ec8a3db2e1b4d7f9fe0947321f6889
https://doi.org/10.1016/j.exer.2008.10.025
https://doi.org/10.1016/j.exer.2008.10.025
Autor:
Kevin F. Webb, Paul J. Donaldson, George Duncan, Haruna Suzuki-Kerr, Jeremy D. Rhodes, Rebecca G. Hu, David J. Collison
Publikováno v:
Experimental Eye Research. 87:137-146
Extracellular ATP has been shown to mobilize intracellular Ca(2+) in cultured ovine lens epithelial cells and in human lens epithelium, suggesting a role for purines in the modulation of lens transparency. In this study, we characterized the expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e7c5f527dae3c595908a14c5475c4d7
https://doi.org/10.1016/j.exer.2008.05.008
https://doi.org/10.1016/j.exer.2008.05.008
Publikováno v:
Human Molecular Genetics. 15:3559-3568
Although cataract is a characteristic feature of myotonic dystrophy type 1 (DM1), little is known of the underlying mechanisms. We generated four lens epithelial cell lines derived from DM1 cataracts and two from age-matched, non-DM cataracts. Small-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53086056bf73f787750a82c930de4806
https://doi.org/10.1093/hmg/ddl432
https://doi.org/10.1093/hmg/ddl432
Publikováno v:
Annals of Botany. 84:109-116
The physical pathway of a systemic signal linking local wounding and systemic synthesis of proteinase inhibitors was investigated in tomato (Lycopersicon esculentum Mill. ‘Moneymaker’) plants. Lucifer Yellow was used to visualize wound induced fl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::864980db4a0e559d73dcca19a4df60cf
https://doi.org/10.1006/anbo.1999.0900
https://doi.org/10.1006/anbo.1999.0900
Autor:
Julie Sanderson, Jeremy D. Rhodes, I. Michael Wormstone, Vincent Moulton, Martin Lott, Sarah L. Russell, David C Broadway
Publikováno v:
Human molecular genetics. 21(4)
Myotonic dystrophy (DM) is caused by a triplet repeat expansion in the non-coding region of either the DMPK (DM1) or CNBP (DM2) gene. Transcription of the expanded region causes accumulation of double-stranded RNA (dsRNA) in DM cells. We sought to de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc820721d3854b7cf90a53706b2232bb
https://pubmed.ncbi.nlm.nih.gov/22062891
https://pubmed.ncbi.nlm.nih.gov/22062891
Publikováno v:
Acta Ophthalmologica. 89
Purpose Raised intraocular pressure is the major risk factor for glaucoma. It is therefore vitally important to understand how increased pressure impacts on retinal ganglion cells (RGC) viability. These experiments investigate the effect of “pure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::714fbab3d2bf76f16f855a0599ecdd46
https://doi.org/10.1111/j.1755-3768.2011.2255.x
https://doi.org/10.1111/j.1755-3768.2011.2255.x
Volume homeostasis is essential for the preservation of lens transparency and this is of particular significance to anadromous fish species where migration from freshwater to seawater presents severe osmotic challenges. In Atlantic salmon ( Salmo sal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8d5eb8265f0bd36bb947cae432cf3a7
https://ueaeprints.uea.ac.uk/id/eprint/28409/
https://ueaeprints.uea.ac.uk/id/eprint/28409/
Lenses of adult Atlantic salmon fed with a plant oil and plant protein-based diet (plant diet) were compared to lenses of fish fed a diet based on traditional marine ingredients (marine diet) with respect to biochemical composition and functionality
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ffab8c02aa3365656e3c2dc30bc8db3
https://ueaeprints.uea.ac.uk/id/eprint/28410/
https://ueaeprints.uea.ac.uk/id/eprint/28410/