Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Jeremy D Burgess"'
Autor:
Olivia J Conway, Minerva M Carrasquillo, Xue Wang, Jenny M Bredenberg, Joseph S Reddy, Samantha L Strickland, Curtis S Younkin, Jeremy D Burgess, Mariet Allen, Sarah J Lincoln, Thuy Nguyen, Kimberly G Malphrus, Alexandra I Soto, Ronald L Walton, Bradley F Boeve, Ronald C Petersen, John A Lucas, Tanis J Ferman, William P Cheshire, Jay A van Gerpen, Ryan J Uitti, Zbigniew K Wszolek, Owen A Ross, Dennis W Dickson, Neill R Graff-Radford, Nilüfer Ertekin-Taner
Publikováno v:
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-12 (2018)
Abstract Background Rare coding variants ABI3_rs616338-T and PLCG2_rs72824905-G were identified as risk or protective factors, respectively, for Alzheimer’s disease (AD). Methods We tested the association of these variants with five neurodegenerati
Externí odkaz:
https://doaj.org/article/26aae77c26cb4a6c9e381ff00070adea
Autor:
Kshama Gupta, Ralph B. Perkerson, Tammee M. Parsons, Ramacharan Angom, Danilyn Amerna, Jeremy D. Burgess, Yingxue Ren, Pamela J. McLean, Debabrata Mukhopadhyay, Prasanna Vibhute, Zbigniew K. Wszolek, Abba C. Zubair, Alfredo Quiñones-Hinojosa, Takahisa Kanekiyo
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-24 (2024)
Abstract Background Radiation therapy is the standard of care for central nervous system tumours. Despite the success of radiation therapy in reducing tumour mass, irradiation (IR)-induced vasculopathies and neuroinflammation contribute to late-delay
Externí odkaz:
https://doaj.org/article/24c38dbdcbff4be1bdca3df216a51ac3
Autor:
Jeremy D. Burgess, Danilyn Amerna, Emily S. Norton, Tammee M. Parsons, Ralph B. Perkerson, Ayman H. Faroqi, Zbigniew K. Wszolek, Hugo Guerrero Cazares, Takahisa Kanekiyo, Marion Delenclos, Pamela J. McLean
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Background Mesenchymal stromal cells (MSCs) have a dynamic secretome that plays a critical role in tissue repair and regeneration. However, studying the MSC secretome in mixed-culture disease models remains challenging. This study aimed to d
Externí odkaz:
https://doaj.org/article/26b95de1f2774f8b9a09c407294b15bf
Autor:
Sara J. Fagen, Jeremy D. Burgess, Melina J. Lim, Danilyn Amerna, Zeynep B. Kaya, Ayman H. Faroqi, Priyanka Perisetla, Natasha N. DeMeo, Iva Stojkovska, Drew J. Quiriconi, Joseph R. Mazzulli, Marion Delenclos, Suelen L. Boschen, Pamela J. McLean
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
BackgroundIntracytoplasmic inclusions comprised of aggregated alpha-synuclein (αsyn) represent a key histopathological feature of neurological disorders collectively termed “synucleinopathies,” which includes Parkinson’s disease (PD). Mutation
Externí odkaz:
https://doaj.org/article/2969623c54014de0ac6153319e52265f
Autor:
Jae-Hyeon Park, Jeremy D. Burgess, Ayman H. Faroqi, Natasha N. DeMeo, Fabienne C. Fiesel, Wolfdieter Springer, Marion Delenclos, Pamela J. McLean
Publikováno v:
Molecular Neurodegeneration, Vol 15, Iss 1, Pp 1-19 (2020)
Abstract Background Misfolding and aggregation of the presynaptic protein alpha-synuclein (αsyn) is a hallmark of Parkinson’s disease (PD) and related synucleinopathies. Although predominantly localized in the cytosol, a body of evidence has shown
Externí odkaz:
https://doaj.org/article/60b1e65ccc0c4003b48d0247a385a231
Autor:
Yunjung Jin, Fuyao Li, Berkiye Sonoustoun, Naveen Chandra Kondru, Yuka A. Martens, Wenhui Qiao, Michael G. Heckman, Tadafumi C. Ikezu, Zonghua Li, Jeremy D. Burgess, Danilyn Amerna, Justin O’Leary, Michael A. DeTure, Jing Zhao, Pamela J. McLean, Dennis W. Dickson, Owen A. Ross, Guojun Bu, Na Zhao
Publikováno v:
Acta Neuropathologica. 143:641-662
Approximately half of Alzheimer’s disease (AD) brains have concomitant Lewy pathology at autopsy, suggesting that α-synuclein (α-SYN) aggregation is a regulated event in the pathogenesis of AD. Genome-wide association studies revealed that the ε
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe046db23f2c71b438ae91254c8dc0a3
https://doi.org/10.1007/s00401-022-02421-8
https://doi.org/10.1007/s00401-022-02421-8
In Vivo Detection of Extracellular Adenosine Triphosphate in a Mouse Model of Traumatic Brain Injury
Autor:
Francesco Di Virgilio, Melina J. Lim, Pamela J. McLean, Emma C. Kee, Ridong Chen, Jeremy D. Burgess, Jannifer H. Lee, Ayman H. Faroqi, Marion Delenclos
Publikováno v:
Journal of Neurotrauma
Traumatic brain injury (TBI) is traditionally characterized by primary and secondary injury phases, both contributing to pathological and morphological changes. The mechanisms of damage and chronic consequences of TBI remain to be fully elucidated, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04fb17de9b191dfbd4088f253a7dadd1
https://doi.org/10.1089/neu.2020.7226
https://doi.org/10.1089/neu.2020.7226
Autor:
Karen N. McFarland, Paramita Chakrabarty, Nicholas T. Seyfried, Xue Wang, Gilbert S. Omenn, Jeremy D. Burgess, Steven G. Younkin, Todd E. Golde, Cory C. Funk, Hong-Dong Li, Yona Levites, Nathan D. Price, Nilufer Ertekin-Taner, Dennis W. Dickson, Allan I. Levey, James J. Lah, Eric B. Dammer, Mariet Allen, Duc M. Duong, Minerva M. Carrasquillo
Publikováno v:
Alzheimer's & Dementia
Intron retention (IR) has been implicated in the pathogenesis of complex diseases such as cancers; its association with Alzheimer's disease (AD) remains unexplored. We performed genome‐wide analysis of IR through integrating genetic, transcriptomic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6fc9eee42fe1fad8a102cc751d2b905
http://europepmc.org/articles/PMC8248162
http://europepmc.org/articles/PMC8248162
Autor:
Ronald C. Petersen, Mariet Allen, Kwangsik Nho, Liana G. Apostolova, Xue Wang, Tatiana Foroud, Isaac M. Neuhaus, Aiqing He, Kelley Faber, Simon Lovestone, Shannon L. Risacher, Sungeun Kim, Lisu Wang, Nilufer Ertekin-Taner, Jeremy D. Burgess, Zhenhao Qi, Katie Lunnon, Michael W. Weiner, Vishal Patel, Andrew Simmons, Kelly N.H. Nudelman, Kuang Lin, Andrew J. Saykin, Angela Hodges
Publikováno v:
Alzheimer's & dementia : the journal of the Alzheimer's Association, vol 16, iss 9
Alzheimers Dement
Alzheimers Dement
INTRODUCTION Abnormal gene expression patterns may contribute to the onset and progression of late-onset Alzheimer's disease (LOAD). METHODS We performed transcriptome-wide meta-analysis (N = 1440) of blood-based microarray gene expression profiles a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f3eb16e9b4623ae689186c11f708cbf
https://doi.org/10.1002/alz.12092
https://doi.org/10.1002/alz.12092
Autor:
Yunjung, Jin, Fuyao, Li, Berkiye, Sonoustoun, Naveen Chandra, Kondru, Yuka A, Martens, Wenhui, Qiao, Michael G, Heckman, Tadafumi C, Ikezu, Zonghua, Li, Jeremy D, Burgess, Danilyn, Amerna, Justin, O'Leary, Michael A, DeTure, Jing, Zhao, Pamela J, McLean, Dennis W, Dickson, Owen A, Ross, Guojun, Bu, Na, Zhao
Publikováno v:
Acta neuropathologica. 143(6)
Approximately half of Alzheimer's disease (AD) brains have concomitant Lewy pathology at autopsy, suggesting that α-synuclein (α-SYN) aggregation is a regulated event in the pathogenesis of AD. Genome-wide association studies revealed that the ε4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::30856c316aaa01643431664cb386d7eb
https://pubmed.ncbi.nlm.nih.gov/35471463
https://pubmed.ncbi.nlm.nih.gov/35471463