Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jeremy Barton"'
Autor:
Mario Sznol, Harriet Kluger, Igor Puzanov, Gerald S Falchook, Ryan Sullivan, Matthew H Taylor, Justin C Moser, Aaron M Ring, Virginia E Paton, David Chonzi, Brage Garofalo, Mark Sonnemann, Hirdesh Uppal, Jeremy Barton, Beatrice Y McQueen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/c9d6a589d3ec4c688bdb430c28cf8a3d
Autor:
Jeremy Barton, D. Sebastian Arias, Chamani Niyangoda, Gustavo Borjas, Nathan Le, Saefallah Mohamed, Martin Muschol
Publikováno v:
Biomolecules, Vol 9, Iss 10, p 539 (2019)
Assembly of amyloid fibrils and small globular oligomers is associated with a significant number of human disorders that include Alzheimer’s disease, senile systemic amyloidosis, and type II diabetes. Recent findings implicate small amyloid oligome
Externí odkaz:
https://doaj.org/article/1f4f2cbb7b6d48f4a94df7c972a8d30d
Autor:
James G. Christensen, Peter Olson, Pasi A. Jänne, Kyriakos P. Papadopoulos, Piro Lito, Sai-Hong Ignatius Ou, Melissa L. Johnson, Igor I. Rybkin, Matthew A. Marx, Douglas P. Cassidy, Emanuel F. Patricoin, Elisa Baldelli, Mariaelena Pierobon, Jeremy Barton, Richard C. Chao, Karen Velastagui, Adam Pavlicek, Julio Fernandez-Banet, Sole Gatto, Yaohua Xue, Guy P. Vigers, John P. Fischer, Jay B. Fell, Michael R. Burkard, Joshua A. Ballard, Brian R. Baer, Vickie Bowcut, Niranjan Sudhakar, David M. Briere, Ruth Aranda, Andrew Calinisan, Lauren Hargis, Lars D. Engstrom, Jill Hallin
Supplementary Composite Figure File
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::095624453d8ad8530fb345958c4cd8b6
https://doi.org/10.1158/2159-8290.22535530.v1
https://doi.org/10.1158/2159-8290.22535530.v1
Autor:
James G. Christensen, Peter Olson, Pasi A. Jänne, Kyriakos P. Papadopoulos, Piro Lito, Sai-Hong Ignatius Ou, Melissa L. Johnson, Igor I. Rybkin, Matthew A. Marx, Douglas P. Cassidy, Emanuel F. Patricoin, Elisa Baldelli, Mariaelena Pierobon, Jeremy Barton, Richard C. Chao, Karen Velastagui, Adam Pavlicek, Julio Fernandez-Banet, Sole Gatto, Yaohua Xue, Guy P. Vigers, John P. Fischer, Jay B. Fell, Michael R. Burkard, Joshua A. Ballard, Brian R. Baer, Vickie Bowcut, Niranjan Sudhakar, David M. Briere, Ruth Aranda, Andrew Calinisan, Lauren Hargis, Lars D. Engstrom, Jill Hallin
Despite decades of research, efforts to directly target KRAS have been challenging. MRTX849 was identified as a potent, selective, and covalent KRASG12C inhibitor that exhibits favorable drug-like properties, selectively modifies mutant cysteine 12 i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd866fa6fe03bc0849986ce88d5870c4
https://doi.org/10.1158/2159-8290.c.6547879.v1
https://doi.org/10.1158/2159-8290.c.6547879.v1
Autor:
Chamani Niyangoda, Piyush Koria, Nabila Bushra, Kanchana Karunarathne, Fadia Fakhre, Jeremy Barton, Graham Strauss, Martin Muschol
Publikováno v:
RSC Chemical Biology
There is compelling evidence that small oligomeric aggregates, emerging during the assembly of amyloid fibrils and plaques, are important molecular pathogens in many amyloid diseases. While significant progress has been made in revealing the mechanis
Autor:
Jill, Hallin, Lars D, Engstrom, Lauren, Hargis, Andrew, Calinisan, Ruth, Aranda, David M, Briere, Niranjan, Sudhakar, Vickie, Bowcut, Brian R, Baer, Joshua A, Ballard, Michael R, Burkard, Jay B, Fell, John P, Fischer, Guy P, Vigers, Yaohua, Xue, Sole, Gatto, Julio, Fernandez-Banet, Adam, Pavlicek, Karen, Velastagui, Richard C, Chao, Jeremy, Barton, Mariaelena, Pierobon, Elisa, Baldelli, Emanuel F, Patricoin, Douglas P, Cassidy, Matthew A, Marx, Igor I, Rybkin, Melissa L, Johnson, Sai-Hong Ignatius, Ou, Piro, Lito, Kyriakos P, Papadopoulos, Pasi A, Jänne, Peter, Olson, James G, Christensen
Publikováno v:
Cancer discovery. 10(1)
Despite decades of research, efforts to directly target KRAS have been challenging. MRTX849 was identified as a potent, selective, and covalent KRAS
Autor:
Chamani Niyangoda, D. Sebastian Arias, Martin Muschol, Nathan Le, Gustavo Borjas, Saefallah Mohamed, Jeremy Barton
Publikováno v:
Biomolecules
Biomolecules, Vol 9, Iss 10, p 539 (2019)
Volume 9
Issue 10
Biomolecules, Vol 9, Iss 10, p 539 (2019)
Volume 9
Issue 10
Assembly of amyloid fibrils and small globular oligomers is associated with a significant number of human disorders that include Alzheimer&rsquo
s disease, senile systemic amyloidosis, and type II diabetes. Recent findings implicate small amyloi
s disease, senile systemic amyloidosis, and type II diabetes. Recent findings implicate small amyloi
Master Today's Best Practices for Building Reusable.NET Frameworks, Libraries, and Components “.NET Core [contains] advances important to cloud application developers: performance, resource utilization, container support, and others. This third edi
Publikováno v:
Drug discovery today. 21(12)
With 80-90% of drugs entering the clinic not meeting regulatory approval (a high cost of failure), there is a major need for innovation in the clinical development space. Features of the new era of practice-changing innovation in oncology have includ
Autor:
Carolyn M. Matthews, Russell J. Schilder, Kye Gilder, Richard T. Penson, Rameshraja Palaparthy, Artemios Vassos, Minal A. Barve, Steffan Ho, Sara Weymer, Ernst Lengyel, Jeremy Barton, Katherine M. Bell-McGuinn, William McAuliffe, Lucy Gilbert
Publikováno v:
Gynecologic Oncology. 121:273-279
This phase II, multicenter, single-arm, two-stage study in platinum-resistant, advanced epithelial ovarian or primary peritoneal cancer evaluated the efficacy, safety, and tolerability of weekly single-agent volociximab. Pharmacokinetic/pharmacodynam