Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jeremy A. Whitson"'
Autor:
Monica Sanchez-Contreras, Mariya T Sweetwyne, Kristine A Tsantilas, Jeremy A Whitson, Matthew D Campbell, Brenden F Kohrn, Hyeon Jeong Kim, Michael J Hipp, Jeanne Fredrickson, Megan M Nguyen, James B Hurley, David J Marcinek, Peter S Rabinovitch, Scott R Kennedy
Publikováno v:
eLife, Vol 12 (2023)
Accumulation of somatic mutations in the mitochondrial genome (mtDNA) has long been proposed as a possible mechanism of mitochondrial and tissue dysfunction that occurs during aging. A thorough characterization of age-associated mtDNA somatic mutatio
Externí odkaz:
https://doaj.org/article/760dc4a6fddb4876a45723742a0cefcc
Autor:
Jeremy A. Whitson, Richard Johnson, Lu Wang, Theo K. Bammler, Shin-Ichiro Imai, Huiliang Zhang, Jeanne Fredrickson, Elena Latorre-Esteves, Alessandro Bitto, Michael J. MacCoss, Peter S. Rabinovitch
Publikováno v:
GeroScience
We analyzed the effects of aging on protein abundance and acetylation, as well as the ability of the mitochondrial-targeted drugs elamipretide (SS-31) and nicotinamide mononucleotide (NMN) to reverse aging-associated changes in mouse hearts. Both dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c5db666e279b22bc3cdf8c5a4d9c7b1
https://doi.org/10.1007/s11357-022-00564-w
https://doi.org/10.1007/s11357-022-00564-w
Autor:
Mariya T Sweetwyne, Monica Sanchez-Contreras, Kristine A Tsantilas, Jeremy A Whitson, Matthew D Campbell, Brenden F Kohrn, Hyeon Jeong Kim, Michael J Hipp, Jeanne Fredrickson, Megan M Nguyen, James B Hurley, David J Marcinek, Peter S Rabinovitch, Scott R Kennedy
Publikováno v:
eLife. 12
Accumulation of somatic mutations in the mitochondrial genome (mtDNA) has long been proposed as a possible mechanism of mitochondrial and tissue dysfunction that occurs during aging. A thorough characterization of age-associated mtDNA somatic mutatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6eb6b18913036a7868e2d6ba84e32f9b
https://doi.org/10.7554/elife.83395
https://doi.org/10.7554/elife.83395
Autor:
Mariya T Sweetwyne, Monica Sanchez-Contreras, Kristine A Tsantilas, Jeremy A Whitson, Matthew D Campbell, Brenden F Kohrn, Hyeon Jeong Kim, Michael J Hipp, Jeanne Fredrickson, Megan M Nguyen, James B Hurley, David J Marcinek, Peter S Rabinovitch, Scott R Kennedy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0e8ba889f9eeb37340125cee9cbb2e5
https://doi.org/10.7554/elife.83395.sa2
https://doi.org/10.7554/elife.83395.sa2
Autor:
Ana P. Valencia, Jeremy A. Whitson, Shari Wang, Leon Nguyen, Laura J. den Hartigh, Peter S. Rabinovitch, David J. Marcinek
Publikováno v:
Nutrients; Volume 14; Issue 21; Pages: 4645
Aging and poor diet are independent risk factors for heart disease, but the impact of high-sucrose (HS) consumption in the aging heart is understudied. Aging leads to impairments in mitochondrial function that result in muscle dysfunction (e.g., card
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05a62f7b1ec93c5c54aebea36bcddeab
https://pubmed.ncbi.nlm.nih.gov/36364920
https://pubmed.ncbi.nlm.nih.gov/36364920
Autor:
Monica Sanchez-Contreras, Mariya T. Sweetwyne, Kristine A. Tsantilas, Jeremy A. Whitson, Matthew D. Campbell, Brendan F. Kohrn, Hyeon Jeong Kim, Micheal J. Hipp, Jeanne Fredrickson, Megan M. Nguyen, James B. Hurley, David J. Marcinek, Peter S. Rabinovitch, Scott R. Kennedy
Accumulation of somatic mutations in the mitochondrial genome (mtDNA) during aging has long been proposed as a possible mechanism of mitochondrial and tissue dysfunction. A thorough characterization of age-associated mtDNA somatic mutations has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::096eaf33a6859cf4e3c0a95c2a4b66d6
https://doi.org/10.1101/2022.08.30.505884
https://doi.org/10.1101/2022.08.30.505884
Autor:
Monica Sanchez-Contreras, Mariya T. Sweetwyne, Brendan F. Kohrn, Kristine A. Tsantilas, Michael J Hipp, Elizabeth K. Schmidt, Jeanne Fredrickson, Jeremy A. Whitson, Matthew D. Campbell, Peter S. Rabinovitch, David J. Marcinek, Scott R. Kennedy
BackgroundMutations in the mitochondrial genome (mtDNA) can cause devastating maternally inherited diseases, while the accumulation of somatic mtDNA mutations is linked to common diseases of aging. Although mtDNA mutations impact human health, the pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e100d739eb4d55a242e77ebcb562530
https://doi.org/10.1101/2021.06.18.448725
https://doi.org/10.1101/2021.06.18.448725