Zobrazeno 1 - 10
of 307
pro vyhledávání: '"Jeremy A Sullivan"'
Autor:
Kelsey J. Solomon, Jeremy C. Sullivan, Edward P. Gardiner, Mark C. Scott, Rebecca J. Bixby, Seth J. Wenger, C. Rhett Jackson, Catherine M. Pringle
Publikováno v:
Ecological Indicators, Vol 168, Iss , Pp 112753- (2024)
Land use/land cover change from forested to developed land is a major threat to freshwater biodiversity globally. However, existing research has focused on high-density development in urban centers. We know less about how low-density development affe
Externí odkaz:
https://doaj.org/article/8929b3337fd3491bb5611ffe1e931d3c
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/27d454c3b68c4291bfda3b83ddead810
Autor:
Do Hoon Kwon, Feng Zhang, Brett A. McCray, Shasha Feng, Meha Kumar, Jeremy M. Sullivan, Wonpil Im, Charlotte J. Sumner, Seok-Yong Lee
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Crosstalk between ion channels and small GTPases is critical during homeostasis and disease, but little is known about the structural underpinnings of these interactions. TRPV4 is a polymodal, calcium-permeable cation channel that has emerge
Externí odkaz:
https://doaj.org/article/331aacbb49b14346b60ba84795aa8594
Autor:
William J. Burlingham, PhD, Ewa Jankowska-Gan, MS, John H. Fechner, MS, Christopher J. Little, MD, Jianxin Wang, PhD, Seungpyo Hong, PhD, Miraf Molla, BS, Jeremy A. Sullivan, PhD, David P. Foley, MD
Publikováno v:
Transplantation Direct, Vol 9, Iss 6, p e1475 (2023)
Background. Here we test the hypothesis that, like CD81-associated “latent” IL35, the transforming growth factor (TGF)β:latency-associated peptide (LAP)/glycoprotein A repetitions predominant (GARP) complex was also tethered to small extracellul
Externí odkaz:
https://doaj.org/article/55c62bbd8b1e4c159f6be1fe92b81bef
Autor:
Adam W. McCrimmon
Publikováno v:
Journal of Psychoeducational Assessment. 29:188-190
Autor:
Brett A. McCray, Erika Diehl, Jeremy M. Sullivan, William H. Aisenberg, Nicholas W. Zaccor, Alexander R. Lau, Dominick J. Rich, Benedikt Goretzki, Ute A. Hellmich, Thomas E. Lloyd, Charlotte J. Sumner
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
TRPV4 dominant mutations cause neuropathy. Here, the authors show that TRPV4 binds and interacts with RhoA, modulating the actin cytoskeleton. Neuropathy-causing mutations of TRPV4 disrupt this complex, leading to RhoA activation and impairment of ne
Externí odkaz:
https://doaj.org/article/c12c32fb25af4c0fbec8907050b017a1
Autor:
Brian M. Woolums, Brett A. McCray, Hyun Sung, Masashi Tabuchi, Jeremy M. Sullivan, Kendra Takle Ruppell, Yunpeng Yang, Catherine Mamah, William H. Aisenberg, Pamela C. Saavedra-Rivera, Bryan S. Larin, Alexander R. Lau, Douglas N. Robinson, Yang Xiang, Mark N. Wu, Charlotte J. Sumner, Thomas E. Lloyd
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Mutations in the TRPV4 channel cause inherited neurodegeneration syndromes, but the molecular mechanisms are unknown. Here the authors reveal that TRPV4 activation causes dose-dependent, CaMKII-mediated neuronal dysfunction and axonal degeneration vi
Externí odkaz:
https://doaj.org/article/27caf567bfbb4b33b6d71b47ffe0ae8f
Donor HLA−DR Drives the Development of De Novo Autoimmunity Following Lung and Heart Transplantation
Autor:
Ewa Jankowska−Gan, MS, Vrushali V. Agashe, PhD, Diego A. Lema, MD, Ying Zhou, MS, Laura Gonzalez Bosc, PhD, Jeremy A. Sullivan, PhD, Daniel S. Greenspan, PhD, William J. Burlingham, PhD
Publikováno v:
Transplantation Direct, Vol 6, Iss 10, p e607 (2020)
Background. Individuals harbor preexisting HLA−DR/DQ−restricted responses to collagen type V (ColV) mediated by Th17 cells under Treg control, both specific to peptides that bind to inherited HLA class II antigens. Yet after transplant, the donor
Externí odkaz:
https://doaj.org/article/440bd605fad843e1bb8e3d2b1e36fbab
Autor:
Jeremy A. Sullivan, David P. AlAdra, Brian M. Olson, Douglas G. McNeel, William J. Burlingham
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Originally identified as lymphocyte regulation of fellow lymphocytes, our understanding of infectious tolerance has undergone significant evolutions in understanding since being proposed in the early 1970s by Gershon and Kondo and expanded upon by He
Externí odkaz:
https://doaj.org/article/9bd64808cfef4ef380e337f25657c867
Autor:
Jeremy A. Sullivan, Yusuke Tomita, Ewa Jankowska-Gan, Diego A. Lema, Matt P. Arvedson, Ashita Nair, William Bracamonte-Baran, Ying Zhou, Kristy K. Meyer, Weixiong Zhong, Deepali V. Sawant, Andrea L. Szymczak-Workman, Qianxia Zhang, Creg J. Workman, Seungpyo Hong, Dario A.A. Vignali, William J. Burlingham
Publikováno v:
Cell Reports, Vol 30, Iss 4, Pp 1039-1051.e5 (2020)
Summary: Interleukin-35 (IL-35) is an immunosuppressive cytokine composed of Epstein-Barr-virus-induced protein 3 (Ebi3) and IL-12α chain (p35) subunits, yet the forms that IL-35 assume and its role in peripheral tolerance remain elusive. We induce
Externí odkaz:
https://doaj.org/article/19bc2a5483074d60bb874b0ead25e86d