Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Jeremy, Parker"'
Autor:
Yinhan Luo, Sina Safabakhsh, Alessia Palumbo, Céline Fiset, Carol Shen, Jeremy Parker, Leonard J. Foster, Zachary Laksman
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5964 (2024)
Males and females exhibit intrinsic differences in the structure and function of the heart, while the prevalence and severity of cardiovascular disease vary in the two sexes. However, the mechanisms of this sex-based dimorphism are yet to be elucidat
Externí odkaz:
https://doaj.org/article/a02d5295efc24761a1fb5f14d7a58da6
Autor:
Fahad Alajmi, Mehima Kang, James Dundas, Alexander Haenel, Jeremy Parker, Philipp Blanke, Fionn Coghlan, John King Khoo, Abdulaziz A. Bin Zaid, Amrit Singh, Bobby Heydari, Darwin Yeung, Thomas M. Roston, Kevin Ong, Jonathon Leipsic, Zachary Laksman
Publikováno v:
Life, Vol 14, Iss 2, p 200 (2024)
Hypertrophic cardiomyopathy (HCM) is a common genetic disorder with a well described risk of sudden cardiac death; however, risk stratification has remained a challenge. Recently, novel parameters in cardiac magnetic resonance imaging (CMR) have show
Externí odkaz:
https://doaj.org/article/386c65b67a494cbca876565724f8293d
Autor:
Sina Safabakhsh, BSc, Darson Du, MD, Janet Liew, BSc, Jeremy Parker, PhD, Cheryl McIlroy, BSN, Elina Khasanova, MD, Praveen Indraratna, MD, Philipp Blanke, MD, Jonathon Leipsic, MD, Jason G. Andrade, MD, Matthew T. Bennett, MD, Nathaniel M. Hawkins, MBChB, MD, Shantabanu Chakrabarti, MD, John Yeung, MD, Marc W. Deyell, MD, Andrew D. Krahn, MD, FHRS, Robert Moss, MD, Kevin Ong, MD, Zachary Laksman, MD, MSc
Publikováno v:
CJC Open, Vol 4, Iss 3, Pp 305-314 (2022)
Background: Sudden cardiac death (SCD) risk stratification in hypertrophic cardiomyopathy (HCM) currently relies on arrhythmic burden quantification by 24 or 48-hour Holter monitoring. Whether this approach adequately captures arrhythmic burden, comp
Externí odkaz:
https://doaj.org/article/c1170a9da7514c05b8db6278b2e4971f
Autor:
Matthew Cheung, Ali Husain, Darson Du, Christopher O. Y. Li, Jeremy Parker, Adaya Weissler‐Snir, Jeffrey B. Geske, Kevin Ong, Zachary Laksman
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 19 (2022)
Externí odkaz:
https://doaj.org/article/24bd57bd3e144893ae2fffe9595637d0
Autor:
Claire M. Patterson, Srividya B. Balachander, Iain Grant, Petar Pop-Damkov, Brian Kelly, William McCoull, Jeremy Parker, Michael Giannis, Kathryn J. Hill, Francis D. Gibbons, Edward J. Hennessy, Paul Kemmitt, Alexander R. Harmer, Sonya Gales, Stuart Purbrick, Sean Redmond, Matthew Skinner, Lorraine Graham, J. Paul Secrist, Alwin G. Schuller, Shenghua Wen, Ammar Adam, Corinne Reimer, Justin Cidado, Martin Wild, Eric Gangl, Stephen E. Fawell, Jamal Saeh, Barry R. Davies, David J. Owen, Marianne B. Ashford
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Claire Patterson et al. present the design and development of AZD0466, a drug-dendrimer conjugate, and use preclinical and mathematical models to determine the optimal release rate of the drug from the dendrimer carrier for maximal therapeutic index
Externí odkaz:
https://doaj.org/article/722de1f4d6464ec9a94bce51fe4fc356
A Kiosk Station for the Assessment of Multiple Cognitive Domains and Cognitive Enrichment of Monkeys
Autor:
Thilo Womelsdorf, Christopher Thomas, Adam Neumann, Marcus R. Watson, Kianoush Banaie Boroujeni, Seyed A. Hassani, Jeremy Parker, Kari L. Hoffman
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 15 (2021)
Nonhuman primates (NHP’s) are self-motivated to perform cognitive tasks on touchscreens in their animal housing setting. To leverage this ability, fully integrated hardware and software solutions are needed that work within housing and husbandry ro
Externí odkaz:
https://doaj.org/article/0740adc334894e20b7b4d68ec8ff82fe
Autor:
Jeffrey Lam, Marion van den Bosch, Joanna Wegrzyn, Jeremy Parker, Rawa Ibrahim, Kate Slowski, Linda Chang, Sergio Martinez-Høyer, Gianluigi Condorelli, Mark Boldin, Yu Deng, Patricia Umlandt, Megan Fuller, Aly Karsan
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Myelodysplastic syndrome (MDS) is characterized by altered hematopoietic stem cell (HSC) and hematopoietic progenitor cell (HPC) regulation and reduction of miR-143 and miR-145 in some subtypes. Here the authors show that miR-143/145 loss leads to HS
Externí odkaz:
https://doaj.org/article/790c5842cee2493c94acd0bef130e50e
Autor:
Brianna Davies, Jacqueline Forman, Cheryl McIlroy, Heather Joe, Sina Safabakhsh, Janet Liew, Jeremy Parker, Darson Du, Jason G Andrade, Matthew T Bennett, Nathaniel M Hawkins, Santabhanu Chakrabarti, John Yeung, Marc W Deyell, Andrew D Krahn, Robert Moss, Kevin Ong, Zachary Laksman
Publikováno v:
European Journal of Cardiovascular Nursing.
Aims Hypertrophic cardiomyopathy (HCM) is the most common inherited heart disease. Insertable cardiac monitors (ICMs) are increasingly used in this population to provide closer monitoring, with the potential for notification systems. However, little
Autor:
Angela Ya-Chi Mo, Hayle Kincross, Xuan Wang, Linda Ya-Ting Chang, Gerben Duns, Harwood Kwan, Tammy Lau, T. Roderick Docking, Jessica Tran, Shane Colborne, Se-Wing Grace Cheng, Shujun Huang, Nadia Gharaee, Elijah Willie, Jihong Jiang, Jeremy Parker, Joshua Bridgers, Davis Wood, Ramon Klein Geltink, Gregg B. Morin, Aly Karsan
Acute myeloid leukemia (AML) is an aggressive cancer with very poor outcomes. Analysis of sequencing data from 1,727 unique AML patients revealed frequent mutations in ubiquitin ligase family genes. Loss of function of the Skp1/Cul1/Fbox (SCF) E3 ubi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0736a5807776c0bfd3d4c8a2ac12b68
https://doi.org/10.1101/2022.09.10.507366
https://doi.org/10.1101/2022.09.10.507366
Autor:
YANG, Jeremy Parker, LEADMAN, Devon, BALLEW, Richard M., SID, Eric, Yanji XU, MATHÉ, Ewy A., Qian ZHU
Publikováno v:
Studies in Health Technology & Informatics; 2023, Vol. 310, p94-98, 5p