Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Jeremy, Goc"'
Autor:
Iva Truxova, Lenka Kasikova, Michal Hensler, Petr Skapa, Jan Laco, Ladislav Pecen, Lucie Belicova, Ivan Praznovec, Michael J. Halaska, Tomas Brtnicky, Eva Salkova, Lukas Rob, Roman Kodet, Jeremy Goc, Catherine Sautes-Fridman, Wolf Herman Fridman, Ales Ryska, Lorenzo Galluzzi, Radek Spisek, Jitka Fucikova
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-13 (2018)
Abstract A high density of tumor-infiltrating CD8+ T cells and CD20+ B cells correlates with prolonged survival in patients with a wide variety of human cancers, including high-grade serous ovarian carcinoma (HGSC). However, the potential impact of m
Externí odkaz:
https://doaj.org/article/0ee748c3b81c416998552dbbd4280c8a
Autor:
Jeremy Goc, Gregory F. Sonnenberg
Publikováno v:
Cancer Immunology Research. 10:1292-1298
Immune checkpoint blockade has revolutionized opportunities for therapeutic intervention in cancer but demonstrates a low frequency of response in most patients and in some common types of tumors. An emerging paradigm supports the notion that trillio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2da835d759b1bbf2001fb35902c0775d
https://doi.org/10.1158/2326-6066.cir-22-0164
https://doi.org/10.1158/2326-6066.cir-22-0164
Autor:
Diane Damotte, Wolf-Herman Fridman, Catherine Sautès-Fridman, Bernhard Mlecnik, Stéphane Oudard, Olivier-Nicolas Pagès, Jean-François Régnard, Virginie Verkarre, Laure Gibault, Jean-François Fléjou, Aurélie Cazes, Jeremy Goc, Hanane Ouakrim, Lucile Crozet, Marc Riquet, Marie-Caroline Dieu-Nosjean, Audrey Lupo, Isabelle Cremer, Marco Alifano, Romain Remark
PDF file - 83K, Baseline characteristics of 52 patients with RCC lung metastasis. * determined by Heng et al.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ae3cdba0d1df1e481f29e51c79150a6
https://doi.org/10.1158/1078-0432.22449435.v1
https://doi.org/10.1158/1078-0432.22449435.v1
Autor:
Diane Damotte, Wolf-Herman Fridman, Catherine Sautès-Fridman, Bernhard Mlecnik, Stéphane Oudard, Olivier-Nicolas Pagès, Jean-François Régnard, Virginie Verkarre, Laure Gibault, Jean-François Fléjou, Aurélie Cazes, Jeremy Goc, Hanane Ouakrim, Lucile Crozet, Marc Riquet, Marie-Caroline Dieu-Nosjean, Audrey Lupo, Isabelle Cremer, Marco Alifano, Romain Remark
PDF file - 90K, Baseline characteristics of 140 patients with CRC lung metastasis. The stage was determined by pathological examination at the time of diagnosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1625287e17f0b550b9798f51e58665bc
https://doi.org/10.1158/1078-0432.22449438
https://doi.org/10.1158/1078-0432.22449438
Autor:
Diane Damotte, Hélène Blons, Ronald Herbst, Isabelle Cremer, Marie-Caroline Dieu-Nosjean, Pierre Laurent-Puig, Claire Germain, Marie Wislez, Jeremy Goc, Karen Leroy, François Goldwasser, Pascaline Boudou-Rouquette, Jennifer Arrondeau, Hanane Ouakrim, Marco Alifano, Nicolas Pécuchet, Audrey Mansuet-Lupo, Jérôme Biton
Purpose: By unlocking antitumor immunity, antibodies targeting programmed cell death 1 (PD-1) exhibit impressive clinical results in non–small cell lung cancer, underlining the strong interactions between tumor and immune cells. However, factors th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0be9933892cb63e1e90c325d91851c84
https://doi.org/10.1158/1078-0432.c.6527516
https://doi.org/10.1158/1078-0432.c.6527516
Autor:
Diane Damotte, Wolf-Herman Fridman, Catherine Sautès-Fridman, Bernhard Mlecnik, Stéphane Oudard, Olivier-Nicolas Pagès, Jean-François Régnard, Virginie Verkarre, Laure Gibault, Jean-François Fléjou, Aurélie Cazes, Jeremy Goc, Hanane Ouakrim, Lucile Crozet, Marc Riquet, Marie-Caroline Dieu-Nosjean, Audrey Lupo, Isabelle Cremer, Marco Alifano, Romain Remark
Purpose: If immune cells are involved in tumor surveillance and have a prognostic impact in most primary tumors, little is known about their significance in metastases. Because patients' survival is heterogeneous, even at metastatic stages, we hypoth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d163c91bf1cbff45754f158b37307a40
https://doi.org/10.1158/1078-0432.c.6521661.v1
https://doi.org/10.1158/1078-0432.c.6521661.v1
Autor:
Diane Damotte, Wolf-Herman Fridman, Catherine Sautès-Fridman, Bernhard Mlecnik, Stéphane Oudard, Olivier-Nicolas Pagès, Jean-François Régnard, Virginie Verkarre, Laure Gibault, Jean-François Fléjou, Aurélie Cazes, Jeremy Goc, Hanane Ouakrim, Lucile Crozet, Marc Riquet, Marie-Caroline Dieu-Nosjean, Audrey Lupo, Isabelle Cremer, Marco Alifano, Romain Remark
PDF file - 101K, Influence of pre-operative patient treatments on the distribution of CD8+, DC-LAMP+ and NKp46+ immune cells in CRC (a, b and c) and RCC lung metastases (d, e and f). 63/140 patients with CRC lung metastases have been treated with neo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa6918657b853ca9501eea1529eefc1
https://doi.org/10.1158/1078-0432.22449447.v1
https://doi.org/10.1158/1078-0432.22449447.v1
Autor:
Diane Damotte, Hélène Blons, Ronald Herbst, Isabelle Cremer, Marie-Caroline Dieu-Nosjean, Pierre Laurent-Puig, Claire Germain, Marie Wislez, Jeremy Goc, Karen Leroy, François Goldwasser, Pascaline Boudou-Rouquette, Jennifer Arrondeau, Hanane Ouakrim, Marco Alifano, Nicolas Pécuchet, Audrey Mansuet-Lupo, Jérôme Biton
Figures S1-12 Tables S1-S4 Supplementary material Supplementary Table S1. Antibodies used in flow cytometry experiments. Supplementary Table S2. Baseline characteristics of the 221 patients with lung adenocarcinoma in each TIP. Supplementary Table S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1793e050c7a3a699dad8917392d81e61
https://doi.org/10.1158/1078-0432.22470311
https://doi.org/10.1158/1078-0432.22470311
Autor:
Diane Damotte, Wolf-Herman Fridman, Catherine Sautès-Fridman, Bernhard Mlecnik, Stéphane Oudard, Olivier-Nicolas Pagès, Jean-François Régnard, Virginie Verkarre, Laure Gibault, Jean-François Fléjou, Aurélie Cazes, Jeremy Goc, Hanane Ouakrim, Lucile Crozet, Marc Riquet, Marie-Caroline Dieu-Nosjean, Audrey Lupo, Isabelle Cremer, Marco Alifano, Romain Remark
PDF file - 88K, Gene expression in lung metastases from CRC and RCC. Expression of genes related to (a) immune cell populations, (b) Th1/Th2 orientations, (c) inflammation and angiogenesis, (d) immunosuppression, (e) cytotoxicity, (f) chemokines/chem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b49f9dd4ac68517177328ad66648e71a
https://doi.org/10.1158/1078-0432.22449444.v1
https://doi.org/10.1158/1078-0432.22449444.v1
Autor:
Diane Damotte, Wolf-Herman Fridman, Catherine Sautès-Fridman, Bernhard Mlecnik, Stéphane Oudard, Olivier-Nicolas Pagès, Jean-François Régnard, Virginie Verkarre, Laure Gibault, Jean-François Fléjou, Aurélie Cazes, Jeremy Goc, Hanane Ouakrim, Lucile Crozet, Marc Riquet, Marie-Caroline Dieu-Nosjean, Audrey Lupo, Isabelle Cremer, Marco Alifano, Romain Remark
PDF file - 107K, Kaplan-Meier curves for the duration of OS according to the presence of CD8+ T cells in the center of the tumor (CT) (a), in the invasive margin (IM) (b) and in combined regions (CT+IM) (c) of CRC lung metastases. Statistical compari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a666fb77c02e8c2466853d9ace3bef6b
https://doi.org/10.1158/1078-0432.22449453.v1
https://doi.org/10.1158/1078-0432.22449453.v1