Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jeremy, Boss"'
Autor:
Miyoung Lee, Jamie A. G. Hamilton, Ganesh R. Talekar, Anthony J. Ross, Langston Michael, Manali Rupji, Bhakti Dwivedi, Sunil S. Raikar, Jeremy Boss, Christopher D. Scharer, Douglas K. Graham, Deborah DeRyckere, Christopher C. Porter, Curtis J. Henry
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Obesity has been reported to promote tumourigenesis and chemoresistance but the underlying mechanisms are not completely understood. Here, the authors show that adipocytes induce Galectin-9 (GAL-9) expression in B-acute lymphoblastic leukaemia (B-ALL
Externí odkaz:
https://doaj.org/article/2dbae7c4d3ee43d79487bfe5ab1bc1e6
Autor:
Anna Cole, Hannah Knochelmann, Amalia Rivera-Reyes, Aubrey Smith, Megan Wyatt, Guillermo Rangel RIvera, Jeremy Boss, Gregory Lesinski, Chrystal Paulos
Publikováno v:
Regular and Young Investigator Award Abstracts.
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93480 (2014)
Aberrant expression of oncogenic 14-3-3 proteins is correlated with poor survival of cancer patients. While the underlying mechanism of the abnormal expression in tumors remains elusive for the six oncogenic 14-3-3 isoforms; the potential involvement
Externí odkaz:
https://doaj.org/article/b4a00469281644ceb54d4fe7aa5cbb91
Autor:
Miyoung, Lee, Jamie A G, Hamilton, Ganesh R, Talekar, Anthony J, Ross, Langston, Michael, Manali, Rupji, Bhakti, Dwivedi, Sunil S, Raikar, Jeremy, Boss, Christopher D, Scharer, Douglas K, Graham, Deborah, DeRyckere, Christopher C, Porter, Curtis J, Henry
Publikováno v:
Nature communications. 13(1)
The incidence of obesity is rising with greater than 40% of the world's population expected to be overweight or suffering from obesity by 2030. This is alarming because obesity increases mortality rates in patients with various cancer subtypes includ
Autor:
Lou-Ella George-Alexander, Anna Kania, Sakeenah Hicks, Tian Mi, Christopher D. Scharer, Jeremy Boss
Publikováno v:
The Journal of Immunology. 204:151.14-151.14
B cell differentiation is a tightly regulated process coordinated by the timed expression of various transcription factors and chromatin accessibility changes mediated by histone modifying enzymes. The histone methyltransferase (HMT) G9a, dimethylate
Publikováno v:
The Journal of Immunology. 202:188.9-188.9
Marginal zone B cells (MZB) are a mature B cell subset that rapidly respond to blood-borne pathogens and are transcriptionally poised to differentiate. Although the transcriptional changes that occur throughout MZB development are known, the correspo
Publikováno v:
The Journal of Immunology. 202:51.10-51.10
The germinal center (GC) is composed of distinct regions with proliferation and affinity maturation of GC B cells (GCB) occurring in the dark zone (DZ) and antigen-mediated selection and commitment of the long-lived plasma cell (LL-PCs) precursors oc
Autor:
Madeline J Price, Christopher D. Scharer, Anna K Kania, Tian Mi, Sakeenah L Hicks, Troy D Randall, Jeremy Boss
Publikováno v:
The Journal of Immunology. 202:123.8-123.8
Immunological memory is a hallmark of the adaptive immune response. Memory B cells (MBC) have increased affinity, expression of costimulatory molecules, and capacity to proliferate and differentiate than their naïve counterparts; however, the epigen
Autor:
Anna Kania, Christopher D. Scharer, Madeline J Price, Robert Richard Haines, Lou-Ella Alexander-George, Jeremy Boss
Publikováno v:
The Journal of Immunology. 202:188.15-188.15
B cell terminal differentiation into antibody secreting plasma cells (ASC) must be properly regulated to ensure robust humoral immune responses against foreign but not self-antigens. While the role of transcription factors in this process is well-est
Publikováno v:
The Journal of Immunology. 196:52.3-52.3
Dendritic cells (DCs) are important mediators of the innate and adaptive immune responses. The network of genes governing the differentiation of these cells has been a topic of discussion for a long time, mainly because of their similarity to other m