Výsledky vyhledávání - "Jeremie Vitte"

Akademický článek

Cold Atmospheric Plasma Induces Growth Arrest and Apoptosis in Neurofibromatosis Type 1-Associated Peripheral Nerve Sheath Tumor Cells

Autor: Brian Na, Blake Haist, Shilp R. Shah, Graeme Sabiston, Steven J. Jonas, Jeremie Vitte, Richard E. Wirz, Marco Giovannini

Publikováno v: Biomedicines, Vol 12, Iss 9, p 1986 (2024)

Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder resulting from mutations in the NF1 gene. Patients harboring these mutations are predisposed to a spectrum of peripheral nerve sheath tumors (PNSTs) originating from Schwann cells, of w

Externí odkaz: https://doaj.org/article/3f901916f71d4f779f1172116037a70f

Zobrazit plný text záznamu

Akademický článek

Cellular mechanisms of heterogeneity in NF2-mutant schwannoma

Autor: Christine Chiasson-MacKenzie, Jeremie Vitte, Ching-Hui Liu, Emily A. Wright, Elizabeth A. Flynn, Shannon L. Stott, Marco Giovannini, Andrea I. McClatchey

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)

Schwannomas are mainly caused by NF2 tumour suppressor inactivation, but they display intratumoural heterogeneity. Here the authors show that this heterogeneity is caused by the loss of polarity and acquisition of different programmes of ErbB ligand

Externí odkaz: https://doaj.org/article/910ca0cc6a5e4813874a61e9dbcdad7c

Zobrazit plný text záznamu

Akademický článek

Timing of Smarcb1 and Nf2 inactivation determines schwannoma versus rhabdoid tumor development

Autor: Jeremie Vitte, Fuying Gao, Giovanni Coppola, Alexander R. Judkins, Marco Giovannini

Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)

SMARCB1 mutations predispose to rhabdoid tumors and schwannomas but the mechanisms underlying the tumor type specificity are unknown. Here the authors present new mouse models and show that early Smarcb1 loss causes rhabdoid tumors whereas loss at la

Externí odkaz: https://doaj.org/article/1faf2971b5a4423bb8a856e7f90310eb

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání