Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Jeremiah Ong'Achwa Machuki"'
Autor:
Marie Louise Ndzie Noah, Richard Mprah, Prosperl Ivette Wowui, Adebayo Oluwafemi Adekunle, Joseph Adu-Amankwaah, Rubin Tan, Zheng Gong, Tao Li, Lu Fu, Jeremiah Ong’achwa Machuki, Shijie Zhang, Hong Sun
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Clinical and experimental studies have shown that the myocardial inflammatory response during pathological events varies between males and females. However, the cellular and molecular mechanisms of these sex differences remain elu
Externí odkaz:
https://doaj.org/article/82cac09ee8a5477d8a81d5b1287b5b17
Publikováno v:
Reviews in Cardiovascular Medicine, Vol 22, Iss 4, Pp 1361-1381 (2021)
Due to their high prevalence and incidence, diabetes and atherosclerosis are increasingly becoming global public health concerns. Atherosclerosis is one of the leading causes of morbidity and disability in type 1 and/or type 2 diabetes patients. Athe
Externí odkaz:
https://doaj.org/article/7e027da7df32414a8f7cb53ad448a522
Autor:
Joseph Adu-Amankwaah, Richard Mprah, Adebayo Oluwafemi Adekunle, Marie Louise Ndzie Noah, Gabriel Komla Adzika, Jeremiah Ong’achwa Machuki, Hong Sun
Publikováno v:
Annals of Medicine, Vol 53, Iss 1, Pp 227-236 (2021)
AbstractThe coronavirus disease-2019 (COVID-19), an infectious disease caused by Severe Acute Respiratory Syndrome Coronavirus 2(SARS-CoV-2), has hit the world very hard by affecting millions of people across countries hence posing a major health thr
Externí odkaz:
https://doaj.org/article/97cb6a03cdc44f43860f26423f563769
Autor:
Ke-Xue Li, Zi-Chao Wang, Jeremiah Ong’Achwa Machuki, Meng-Zhen Li, Yu-Jie Wu, Ming-Kai Niu, Kang-Ying Yu, Qing-Bo Lu, Hai-Jian Sun
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Growing evidence suggests that hypertension is one of the leading causes of cardiovascular morbidity and mortality since uncontrolled high blood pressure increases the risk of myocardial infarction, aortic dissection, hemorrhagic stroke, and chronic
Externí odkaz:
https://doaj.org/article/9bed3beb01a2459183841488705f8e5a
Autor:
Gabriel Komla Adzika, Hongjian Hou, Adebayo Oluwafemi Adekunle, Ruqayya Rizvi, Seyram Yao Adzraku, Kexue Li, Qi-Ming Deng, Richard Mprah, Marie Louise Ndzie Noah, Joseph Adu-Amankwaah, Jeremiah Ong’achwa Machuki, Wenkang Shang, Tongtong Ma, Stephane Koda, Xianluo Ma, Hong Sun
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Chronic catecholamine stress (CCS) induces the occurrence of cardiomyopathy—pathological cardiac hypertrophy (PCH), which is characterized by left ventricular systolic dysfunction (LVSD). Recently, mounting evidence has implicated myocardial inflam
Externí odkaz:
https://doaj.org/article/e795c5c9a88342459dd8487dae8abb71
Autor:
Wenkang Shang, Gabriel Komla Adzika, Yujie Li, Qike Huang, Ningding Ding, Bianca Chinembiri, Mohammad Sajjad Ibn Rashid, Jeremiah Ong'achwa Machuki
Publikováno v:
Cancer Medicine, Vol 8, Iss 15, Pp 6684-6699 (2019)
Abstract At the heart of hepatocellular carcinoma (HCC) lies disruption of signaling pathways at the level of molecules, genes, and cells. Non‐coding RNAs (ncRNAs) have been implicated in the disease progression of HCC. For instance, dysregulated e
Externí odkaz:
https://doaj.org/article/12c1e96048ee4c2fbfa848bb69034901
Autor:
Jeremiah Ong’achwa Machuki, Hong-Yuan Zhang, Juan Geng, Lu Fu, Gabriel Komla Adzika, Lijuan Wu, Wenkang Shang, Jinxia Wu, Li Kexue, Zhiwei Zhao, Hong Sun
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-17 (2019)
Abstract Backgrounds/Aim Male and female hearts have many structural and functional differences. Here, we investigated the role of estrogen (E2) in the mechanisms of sex differences in contraction through the cAMP-L-type Ca2+channel pathway in adult
Externí odkaz:
https://doaj.org/article/ad1339f27ec44e91a2d05802bd1564c0
Autor:
Lin Zhang, Chenfei Li, Liting Yang, Gabriel Komla Adzika, Jeremiah Ong'achwa Machuki, Mingjin Shi, Qi Sun, Hong Sun
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
The incidence of dysfunctional vasomotor diseases has mostly occurred in postmenopausal women but not in premenopausal women. Hence, this study sought to investigate the impact of estrogen deficiency during catecholamine stress on vasomotor function.
Externí odkaz:
https://doaj.org/article/9318aa89bfde4c48b09fa0fee2848222
Autor:
Wenzhen Pan, Na Li, Jeremiah Ong'achwa Machuki, Zhao Liu, Fenglei Gao, Kezhen Ge, Caiyi Zhang, Mengying Fu, Xing Zhang
Publikováno v:
Analytical Chemistry. 93:12103-12115
Despite several attempts, incorporating biological detection that supplies necessary biological information into therapeutic nanotheranostics for hypoxic tumor treatments is considered to be in its infancy. It is therefore imperative to consolidate b
Autor:
Hong Sun, Lili Sang, Hongyuan Zhang, Matthew James Turley, Zhiwei Zhao, Xide Hu, Hongjian Hou, Lijuan Wu, Tingting Zhang, Dongye Li, Lin Han, Jeremiah Ong'achwa Machuki, Lu Fu, Sian E. Harding
Publikováno v:
Journal of Endocrinology. 249:209-222
Currently, there are no conventional treatments for stress-induced cardiomyopathy (SCM, also known as Takotsubo syndrome), and the existing therapies are not effective. The recently discovered G protein-coupled estrogen receptor (GPER) executes the r