Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Jeremiah F. Kelly"'
Publikováno v:
Brain, Behavior, and Immunity. 24:438-443
Self-reported experiences of “everyday” discrimination have been linked to indices of cardiovascular disease and overall mortality and findings have been particularly pronounced for African-American populations. However, the biological mechanisms
Publikováno v:
Neuroepidemiology. 34:43-49
Background: The apolipoprotein E (APOE) ε4 allele is a well-known risk factor for the development of Alzheimer’s disease, but little is known about the association of the ε4 allele with incident mild cognitive impairment (MCI). Objective: Test th
Autor:
Robert S. Wilson, Todd Beck, Aron S. Buchman, Patricia A. Boyle, Jeremiah F. Kelly, David A. Bennett
Publikováno v:
Alzheimer Disease & Associated Disorders. 23:63-69
We tested the hypothesis that apolipoprotein E allele status predicts the rate of motor decline in the elderly. Eight hundred seventy-six older participants without dementia underwent baseline and annual motor testing for up to 10 years. In a general
Autor:
Julia L. Bienias, Julie A. Schneider, Kathleen A. Meeke, Jeremiah F. Kelly, David A. Bennett, Avni Shah, Edwin Soriano
Publikováno v:
Current Alzheimer Research. 5:45-51
Estrogen exerts beneficial effects on the brain throughout life. Studies demonstrate that estrogen is neuroprotective and that reduced brain estrogen activity may influence the clinical course of Alzheimer's disease (AD). Changes in levels of estroge
Autor:
Neelum T. Aggarwal, Zoe Arvanitakis, Aron S. Buchman, Yuxiao Tang, Robert S. Wilson, Jeremiah F. Kelly, Patricia A. Boyle, David A. Bennett
Publikováno v:
Experimental Aging Research. 33:355-371
Recent findings suggest that lower extremity motor dysfunction may be a feature of mild cognitive impairment (MCI), but little is known about the nature and significance of lower extremity motor dysfunction in MCI. The aim of this study was to examin
Autor:
Robert S. Wilson, Jeremiah F. Kelly, Julie A. Schneider, Steven E. Arnold, Yuxiao Tang, David A. Bennett
Publikováno v:
Neuroepidemiology. 27:143-153
Clinical and pathological data from the Rush Memory and Aging Project were used to test the hypothesis that distress proneness is associated with increased risk of Alzheimer’s disease (AD). More than 600 older persons without dementia completed a 6
Publikováno v:
Neuroscience Letters. 381:36-41
Dysregulation of cholesterol homeostasis may be associated with the pathogenesis of coronary artery disease (CAD) and Alzheimers disease (AD). Recently, several single nucleotide polymorphisms (SNPs) in cholesteryl ester transfer protein (CETP) were
Publikováno v:
Journal of Neurochemistry. 69:570-580
Considerable data indicate that oxidative stress and membrane lipid peroxidation contribute to neuronal degeneration in an array of age-related neurodegenerative disorders. In contrast, the impact of subtoxic levels of membrane lipid peroxidation on
Autor:
Aron S. Buchman, Jeremiah F. Kelly, Debra A. Fleischman, Niranjini Rajendran, Lisa L. Barnes, David A. Bennett, Konstantinos Arfanakis, Martha Clare Morris
Publikováno v:
Journal of the American Geriatrics Society. 58:1823-1825
To the editor: Regional cortical thinning occurs in aging1, in Alzheimer’s disease (AD)2 and its prodromal stages2–3, but little is known about its biological basis. This thinning may reflect the presence of neuroinflammation associated with depo