Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jeremiah D. Mitzelfelt"'
Publikováno v:
Psychopharmacology. 231:75-84
Chronic pain is becoming a more common medical diagnosis and is especially prevalent in older individuals. As such, prescribed use of opioids is on the rise, even though the efficacy for pain management in older individuals is unclear.Thus, the prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aed0be621df926bd0263a02e639d251
https://doi.org/10.1007/s00213-013-3208-4
https://doi.org/10.1007/s00213-013-3208-4
Publikováno v:
Experimental Gerontology. 46:65-72
There is growing concern over the increasing use of opioids to treat chronic pain in the elderly primarily because of the potential increased sensitivity to the adverse side effects. Here, we use a preclinical model (male Brown Norway X F344 rats age
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b800dbb28eff0c7386a6bec33c7c90e5
https://doi.org/10.1016/j.exger.2010.10.004
https://doi.org/10.1016/j.exger.2010.10.004
Autor:
Douglas C. Eaton, Jeremiah D. Mitzelfelt, Otor Al-Khalili, Hui-Fang Bao, Billie Jeanne Duke, Megan M. Greenlee
Many hormonal pathways contribute to the regulation of renal epithelial sodium channel (ENaC) function, a key process for maintaining blood volume and controlling blood pressure. In the present study, we examined whether the peptide hormone prolactin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dddccf04f260b4444bdc09d3ca270562
https://europepmc.org/articles/PMC4385885/
https://europepmc.org/articles/PMC4385885/
Publikováno v:
The FASEB Journal. 28
In the renal collecting duct, sodium reabsorption through the epithelial sodium channel (ENaC) creates an osmotic driving force for water reabsorption resulting in increased blood volume and pressu...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cc073e5c812126c4934790386a7f30c
https://doi.org/10.1096/fasebj.28.1_supplement.893.3
https://doi.org/10.1096/fasebj.28.1_supplement.893.3
Publikováno v:
The FASEB Journal. 28
Prolactin (PRL) is a peptide hormone well-known for its role in lactation. PRL also has osmoregulatory actions via alteration of ion and water transport, actions characterized mostly in aquatic lif...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2215f046a01459c8e440311750ecd80
https://doi.org/10.1096/fasebj.28.1_supplement.1181.9
https://doi.org/10.1096/fasebj.28.1_supplement.1181.9
Autor:
Constance S. Harrell, Ling Yu, Billie Jeanne Duke, Gretchen N. Neigh, Douglas C. Eaton, Qiang Yue, Megan M. Greenlee, Jeremiah D. Mitzelfelt
Female sex predisposes individuals to poorer outcomes during respiratory disorders like cystic fibrosis and influenza-associated pneumonia. A common link between these disorders is dysregulation of alveolar fluid clearance via disruption of epithelia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b07b520d954a598010c728e94e2f3a7a
https://europepmc.org/articles/PMC3882529/
https://europepmc.org/articles/PMC3882529/
Publikováno v:
The FASEB Journal. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf07f8ecb5421a25ab82e854e953fc9a
https://doi.org/10.1096/fasebj.27.1_supplement.722.2
https://doi.org/10.1096/fasebj.27.1_supplement.722.2
Publikováno v:
The FASEB Journal. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2d6aef8547f4585c280f4bbccd66493
https://doi.org/10.1096/fasebj.27.1_supplement.1148.7
https://doi.org/10.1096/fasebj.27.1_supplement.1148.7
There are contradictory data regarding older individuals’ sensitivity to pain stimulation and opioid administration. Adult (12–16 months; n = 10) and aged (27–31 months; n = 7) male F344xBN rats were tested in a thermal sensitivity procedure wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d0770279eca1a0cb6f3d272dfc0f733
https://europepmc.org/articles/PMC3391067/
https://europepmc.org/articles/PMC3391067/
Autor:
Firas H, Kobeissy, Jeremiah D, Mitzelfelt, Irina, Fishman, Drake, Morgan, Roger, Gaskins, Zhiqun, Zhang, Mark S, Gold, Kevin K, Wang
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 829
Methamphetamine (METH) is a widely abused psychomotor stimulant. Investigating the effects of METH use on the brain has been applied in different animal models, including rats, mice, and nonhuman primates. Human abuse of METH occurs in different para
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::525d9f5706e9e4ffe91d9345fd3ac1b4
https://pubmed.ncbi.nlm.nih.gov/22231820
https://pubmed.ncbi.nlm.nih.gov/22231820