Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Jeremiah D Degenhardt"'
Autor:
Ying Zhu, Danielle E Dettling, Eilene Kwok, Lucy Quach, Aakash Datt, Jeremiah D Degenhardt, Anand Panchal, Pui Seto, Jessica L Krakow, Russell Wall, Brian J Hillier, Maia Vinogradova, Robert B DuBridge, Chad May
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 6 (2022)
Externí odkaz:
https://doaj.org/article/c0d4502e962a41b08a1e2dfef4485839
Autor:
Xin Ma, Joanna L Kelley, Kirsten Eilertson, Shaila Musharoff, Jeremiah D Degenhardt, André L Martins, Tomas Vinar, Carolin Kosiol, Adam Siepel, Ryan N Gutenkunst, Carlos D Bustamante
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77175 (2013)
To gain insights into evolutionary forces that have shaped the history of Bornean and Sumatran populations of orang-utans, we compare patterns of variation across more than 11 million single nucleotide polymorphisms found by previous mitochondrial an
Externí odkaz:
https://doaj.org/article/7090b00f81ee43a8a09926ee1945932b
Autor:
Adam R Boyko, Pascale Quignon, Lin Li, Jeffrey J Schoenebeck, Jeremiah D Degenhardt, Kirk E Lohmueller, Keyan Zhao, Abra Brisbin, Heidi G Parker, Bridgett M vonHoldt, Michele Cargill, Adam Auton, Andy Reynolds, Abdel G Elkahloun, Marta Castelhano, Dana S Mosher, Nathan B Sutter, Gary S Johnson, John Novembre, Melissa J Hubisz, Adam Siepel, Robert K Wayne, Carlos D Bustamante, Elaine A Ostrander
Publikováno v:
PLoS Biology, Vol 8, Iss 8, p e1000451 (2010)
Domestic dogs exhibit tremendous phenotypic diversity, including a greater variation in body size than any other terrestrial mammal. Here, we generate a high density map of canine genetic variation by genotyping 915 dogs from 80 domestic dog breeds,
Externí odkaz:
https://doaj.org/article/1fa232fafe334e7881e1e97d3f873e57
Autor:
Jeremiah D Degenhardt, Paola de Candia, Adrien Chabot, Stuart Schwartz, Les Henderson, Binhua Ling, Meredith Hunter, Zhaoshi Jiang, Robert E Palermo, Michael Katze, Evan E Eichler, Mario Ventura, Jeffrey Rogers, Preston Marx, Yoav Gilad, Carlos D Bustamante
Publikováno v:
PLoS Genetics, Vol 5, Iss 1, p e1000346 (2009)
Variation in genes underlying host immunity can lead to marked differences in susceptibility to HIV infection among humans. Despite heavy reliance on non-human primates as models for HIV/AIDS, little is known about which host factors are shared and w
Externí odkaz:
https://doaj.org/article/aef92161213745ddaa6043f88e71a440
Autor:
Adam R Boyko, Scott H Williamson, Amit R Indap, Jeremiah D Degenhardt, Ryan D Hernandez, Kirk E Lohmueller, Mark D Adams, Steffen Schmidt, John J Sninsky, Shamil R Sunyaev, Thomas J White, Rasmus Nielsen, Andrew G Clark, Carlos D Bustamante
Publikováno v:
PLoS Genetics, Vol 4, Iss 5, p e1000083 (2008)
Quantifying the distribution of fitness effects among newly arising mutations in the human genome is key to resolving important debates in medical and evolutionary genetics. Here, we present a method for inferring this distribution using Single Nucle
Externí odkaz:
https://doaj.org/article/7d2e6d340ec24e4a8b1cfd2d5ef74e32
Autor:
Eugen Tausch, Viktor Ljungström, Andreas Agathangelidis, Marc Zapatka, Lydia Scarfò, Billy Michael Chelliah Jebaraj, Deyan Y. Yosifov, Annika Müller, Veerendra Munugalavadla, Jeremiah D. Degenhardt, Paolo Ghia, Richard Rosenquist, Stephan Stilgenbauer
Publikováno v:
Blood. 139:3340-3344
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f88466d0a6390f06185c322cc5d799e
https://doi.org/10.1182/blood.2021014550
https://doi.org/10.1182/blood.2021014550
Publikováno v:
Cancer Immunology and Immunotherapy ISBN: 9780128233979
T-cell engagers (TCEs) are highly potent cancer therapeutics. Designed to coengage T-cells and target antigens on tumors, they can eliminate tumors at very low concentrations. While they have demonstrated success in the clinic when pursuing hematolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92f21598811ebe2d215dede844263d8e
https://doi.org/10.1016/b978-0-12-823397-9.00002-8
https://doi.org/10.1016/b978-0-12-823397-9.00002-8
Autor:
Gulzar Ahmad, Nadia Tasnim Ahmed, Amedeo Amedei, Mansoor M. Amiji, Kirtika H. Asrani, Federico Boem, Kevin A. Cassady, Yu Chen, Patty A. Culp, Jeremiah D. Degenhardt, Danielle E. Dettling, Mustafa B.A. Djamgoz, Aatman S. Doshi, Eyad Elkord, Laetitia Firmenich, Lauren M. Gauthier, Hazem E. Ghoneim, Taichiro Goto, Ilse Hernandez-Aguirre, Hae Lin Jang, Yongsheng Li, Xiang Liu, Gerardo G. Mackenzie, Chad May, Lara Scheherazade Milane, Edda Russo, Abbey A. Saadey, Reem Saleh, Varun Sasidharan Nair, Shiladitya Sengupta, Ting Su, Salman M. Toor, Amir Yousif, Shurong Zhou, Guizhi Zhu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a61abb19f336a0ec05483d3a462bf4f
https://doi.org/10.1016/b978-0-12-823397-9.09989-0
https://doi.org/10.1016/b978-0-12-823397-9.09989-0
Autor:
Danielle E Dettling, Eilene Kwok, Lucy Quach, Aakash Datt, Jeremiah D Degenhardt, Anand Panchal, Pui Seto, Jessica L Krakow, Russell Wall, Brian J Hillier, Ying Zhu, Maia Vinogradova, Robert B DuBridge, Chad May
Publikováno v:
Journal for ImmunoTherapy of Cancer. 10:e004336
BackgroundDespite clinical success with T cell engagers (TCEs) targeting hematological malignancies, achieving a safe and efficacious dose in patients with solid tumors remains challenging. Due to potency, low levels of target antigen expression on n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6442899ddb12569f97e7248a2000f18
https://doi.org/10.1136/jitc-2021-004336
https://doi.org/10.1136/jitc-2021-004336
Autor:
Maia Vinogradova, Danielle E. Dettling, Russell Wall, Jessica L. Krakow, Aakash Datt, Elizabeth Pongo, Tseng-Hui T Chen, Andisheh Bagheri, Brian J. Hillier, Patricia Culp, Ying Zhu, Chad May, Robert B. Dubridge, Jeremiah D. Degenhardt, Pui Seto, Anand Panchal
Publikováno v:
mAbs
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Conditionally active COBRA™ (COnditional Bispecific Redirected Activation) T cell engagers are engineered to overcome the limitations of inherently active first-generation T cell engagers, which are unable to discern between tumor and healthy tissu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab2fd557a45866fee279d7f92d7371bd
https://doi.org/10.1080/19420862.2020.1792130
https://doi.org/10.1080/19420862.2020.1792130