Výsledky vyhledávání - "Jeremiah Boles"

Anthracycline treatment of the human monocytic leukemia cell line THP-1 increases phosphatidylserine exposure and tissue factor activity

Autor: Raj S. Kasthuri, Jeremiah Boles, Rachel M. Hollingsworth, Julie C. Williams, Jianguo Wang, A. Phillip Owens, Nigel Mackman, Nigel S. Key, David A. Barcel, Sam L. Glover

Publikováno v: Thrombosis Research. 129:197-203

Introduction Cancer associated thrombosis is a well-recognized phenomenon that results in considerable patient morbidity and mortality. Malignancy conveys an increased risk for thrombosis and chemotherapy further elevates this risk. The pathophysiolo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b63e3b6595a556fe015981ce877741b
https://doi.org/10.1016/j.thromres.2011.06.022

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Pre-analytical and analytical variables affecting the measurement of plasma-derived microparticle tissue factor activity

Autor: D.A. Barcel, Julie C. Williams, Jianguo Wang, Nigel S. Key, Rebecca D. Lee, David Manly, Nigel Mackman, Jeremiah Boles

Publikováno v: Thrombosis Research. 129:80-85

Tissue factor (TF) is a transmembrane protein that is the primary initiator of the coagulation cascade. TF is constitutively expressed on perivascular cells and epithelial cells and activates the clotting cascade in the event of vascular injury [1–

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86c0776b8a233fbe623b18c132cfd377
https://doi.org/10.1016/j.thromres.2011.06.004

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B cell acute lymphocytic leukemia in pregnancy

Autor: Jeremiah Boles, Mark A. Brown, Justin Bottsford-Miller, Arthur M. Baker, Sina Haeri

Publikováno v: Archives of Gynecology and Obstetrics. 284:303-306

Acute lymphocytic leukemia (ALL) is a rare occurrence in pregnancy and can be rapidly fatal if left untreated. The need for immediate treatment of ALL, coupled with the maternal-fetal risks from the chemotherapy regimen render a therapeutic dilemma i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9bbe29e262b39d1cc7f7b49e510009d
https://doi.org/10.1007/s00404-010-1647-2

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PPPS-2013: Pulsed spherical reactor dynamics in a fissionable gas

Autor: Jeremiah Boles, William Culbreth

Publikováno v: 2013 Abstracts IEEE International Conference on Plasma Science (ICOPS).

Summary form only given. Pulsed gaseous fission reactors can be used to provide a transient source of neutrons for research or for power production. A mixture of gaseous, enriched UF6 and He may serve as the fuel and moderator for this design1. By us

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4d9be8edf2e54673dda03b3e34b4183f
https://doi.org/10.1109/plasma.2013.6634998

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Role of Tissue Factor in Venous Thrombosis

Autor: David Manly, Jeremiah Boles, Nigel Mackman

Venous thromboembolism (VTE) is a leading cause of morbidity and mortality worldwide. However, the mechanisms by which clots are formed in the deep veins have not been determined. Tissue factor (TF) is the primary initiator of the coagulation cascade

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dac4cc1acbdb71ada8e05da051052e83
https://europepmc.org/articles/PMC3076951/

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Tissue factor and tissue factor pathway inhibitor as key regulators of global hemostasis: measurement of their levels in coagulation assays

Autor: Raj S. Kasthuri, Jeremiah Boles, Sam L. Glover, Nigel Mackman

Publikováno v: Seminars in thrombosis and hemostasis. 36(7)

The tissue factor (TF)/factor (F)VIIa complex is the primary initiator of coagulation in vivo. Tissue factor pathway inhibitor (TFPI) is the physiological inhibitor of the TF/FVIIa complex. Deficiencies of either TF or TFPI have not been reported in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::083c3a72fd43483190a434037431a0f6
https://pubmed.ncbi.nlm.nih.gov/20978997

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