Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jeremiah Athmer"'
Autor:
Joseph J. O’Connor, Lynden Voth, Jeremiah Athmer, Nicholas M. George, Christopher M. Connelly, Anthony R. Fehr
Publikováno v:
Pathogens, Vol 12, Iss 9, p 1082 (2023)
The continued circulation of SARS-CoV-2 and the increasing frequency of coronavirus (CoV) outbreaks over the decades demonstrates the enduring threat that the CoV family poses. There remains a significant need to develop tools to monitor and prevent
Externí odkaz:
https://doaj.org/article/43672355203640b384d89a8a2fa20a3a
Selective Packaging in Murine Coronavirus Promotes Virulence by Limiting Type I Interferon Responses
Autor:
Jeremiah Athmer, Anthony R. Fehr, Matthew E. Grunewald, Wen Qu, D. Lori Wheeler, Kevin W. Graepel, Rudragouda Channappanavar, Aimee Sekine, Dana Saud Aldabeeb, Michael Gale, Mark R. Denison, Stanley Perlman
Publikováno v:
mBio, Vol 9, Iss 3 (2018)
ABSTRACT Selective packaging is a mechanism used by multiple virus families to specifically incorporate genomic RNA (gRNA) into virions and exclude other types of RNA. Lineage A betacoronaviruses incorporate a 95-bp stem-loop structure, the packaging
Externí odkaz:
https://doaj.org/article/3da1a93d54de4efbb6a33718ce452b29
Autor:
Jeremiah Athmer, Anthony R. Fehr, Matthew Grunewald, Everett Clinton Smith, Mark R. Denison, Stanley Perlman
Publikováno v:
mBio, Vol 8, Iss 1 (2017)
ABSTRACT Coronavirus (CoV) replication and transcription are carried out in close proximity to restructured endoplasmic reticulum (ER) membranes in replication/transcription complexes (RTC). Many of the CoV nonstructural proteins (nsps) are required
Externí odkaz:
https://doaj.org/article/03db014b31c54495bdaf97407c1c54f8
Autor:
Anthony R. Fehr, Rudragouda Channappanavar, Gytis Jankevicius, Craig Fett, Jincun Zhao, Jeremiah Athmer, David K. Meyerholz, Ivan Ahel, Stanley Perlman
Publikováno v:
mBio, Vol 7, Iss 6 (2016)
ABSTRACT ADP-ribosylation is a common posttranslational modification that may have antiviral properties and impact innate immunity. To regulate this activity, macrodomain proteins enzymatically remove covalently attached ADP-ribose from protein targe
Externí odkaz:
https://doaj.org/article/0097247f8f7044de91270e91079a1c7f
Publikováno v:
Virology
ADP-ribosylation is a common post-translational modification, although how it modulates RNA virus infection is not well understood. While screening for ADP-ribosylated proteins during coronavirus (CoV) infection, we detected a ~55 kDa ADP-ribosylated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdd6517e2ef63879c6f8384b49224660
Autor:
Rudragouda Channappanavar, Nitin A. Pagedar, Rahul Vijay, Stanley Perlman, Jeremiah Athmer, Xiaoyang Hua, David K. Meyerholz, Stephen L. Tilley
The nasal mucosa is an important component of mucosal immunity. Immunogenic particles in inspired air are known to activate the local nasal mucosal immune system and can lead to sinonasal inflammation; however, little is known about the effect of thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbfde43e6f583e390808292629083ca6
https://europepmc.org/articles/PMC6124400/
https://europepmc.org/articles/PMC6124400/
Selective Packaging in Murine Coronavirus Promotes Virulence by Limiting Type I Interferon Responses
Autor:
Aimee Sekine, Matthew E. Grunewald, Jeremiah Athmer, Dana Aldabeeb, Kevin W. Graepel, Rudragouda Channappanavar, Wen Qu, D. Lori Wheeler, Anthony R. Fehr, Mark R. Denison, Michael Gale, Stanley Perlman
Publikováno v:
mBio, Vol 9, Iss 3, p e00272-18 (2018)
mBio, Vol 9, Iss 3 (2018)
mBio
mBio, Vol 9, Iss 3 (2018)
mBio
Selective packaging is a mechanism used by multiple virus families to specifically incorporate genomic RNA (gRNA) into virions and exclude other types of RNA. Lineage A betacoronaviruses incorporate a 95-bp stem-loop structure, the packaging signal (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b4e835a077314244d932a33197bfc3e
https://doaj.org/article/0c7edc7255234ff8827fe3a858f18d6d
https://doaj.org/article/0c7edc7255234ff8827fe3a858f18d6d
Autor:
Jeremiah Athmer, Anthony R. Fehr, Rudragouda Channappanavar, Judith M. Phillips, David K. Meyerholz, Stanley Perlman
Publikováno v:
Journal of Virology
All coronaviruses encode a macrodomain containing ADP-ribose-1″-phosphatase (ADRP) activity within the N terminus of nonstructural protein 3 (nsp3). Previous work showed that mouse hepatitis virus strain A59 (MHV-A59) with a mutated catalytic site
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ef614f0202f0a7703b77b77c78fd925
https://doi.org/10.1128/jvi.02596-14
https://doi.org/10.1128/jvi.02596-14
Publikováno v:
Journal of Virology
Viral infection of the central nervous system (CNS) is complicated by the mostly irreplaceable nature of neurons, as the loss of neurons has the potential to result in permanent damage to brain function. However, whether neurons or other cells in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12a8db48fb4ecd6379ebaadb457790cb