Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Jerel Adam Fields"'
Autor:
Bryant Avalos, Jacqueline R. Kulbe, Mary K. Ford, Anna Elizabeth Laird, Kyle Walter, Michael Mante, Jazmin B. Florio, Ali Boustani, Antoine Chaillon, Johannes C. M. Schlachetzki, Erin E. Sundermann, David J. Volsky, Robert A. Rissman, Ronald J. Ellis, Scott L. Letendre, Jennifer Iudicello, Jerel Adam Fields
Publikováno v:
Viruses, Vol 16, Iss 10, p 1509 (2024)
Triggering receptor expressed on myeloid cells 2 (TREM2) is involved in neuroinflammation and HIV-associated neurocognitive impairment (NCI). People with HIV (PWH) using cannabis exhibit lower inflammation and neurological disorders. We hypothesized
Externí odkaz:
https://doaj.org/article/4d637d679e76456dbcdd30adf98db292
Autor:
Armando Garces, Bryan Martinez, Roberto De La Garza, Deepa Roy, Kaylie-Anna Vallee, Jerel Adam Fields, David J. Moore, Hansapani Rodrigo, Upal Roy
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract The United Nations projects that one in every six people will be over the age of 65 by the year 2050. With a rapidly aging population, the risk of Alzheimer's disease (AD) becomes a major concern. AD is a multifactorial disease that involves
Externí odkaz:
https://doaj.org/article/11d3d3eb92894b549065c2cb5539754d
Autor:
Jacqueline Renee Kulbe, Lauren Nguyen, Alexandra Anh Le, Anna Elizabeth Laird, Michael A. Taffe, Jacques D. Nguyen, Jerel Adam Fields
Publikováno v:
Brain Sciences, Vol 13, Iss 11, p 1556 (2023)
E-cigarette use has been marketed as a safer alternative to traditional cigarettes, as a means of smoking cessation, and are used at a higher rate than the general population in people with HIV (PWH). Early growth receptor 2 (EGR2) and Activity-Regul
Externí odkaz:
https://doaj.org/article/d0263fec3a8b4b5a9879a281f21b34c6
Autor:
Jerel Adam Fields, Mary Swinton, Erin E. Sundermann, Nicholas Scrivens, Kaylie-Anna Juliette Vallee, David J. Moore
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
People with HIV (PWH) continue to suffer from dysfunction of the central nervous system, as evidenced by HIV-associated neurocognitive disorder (HAND), despite antiretroviral therapy and suppressed viral loads. As PWH live longer they may also be at
Externí odkaz:
https://doaj.org/article/4afb9e818e594363b6a4c7323f53ff43
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-16 (2020)
Abstract Background HIV-associated neurocognitive disorders (HAND) persist in the era of combined antiretroviral therapy (ART) despite reductions in viral load (VL) and overall disease severity. The mechanisms underlying HAND in the ART era are not w
Externí odkaz:
https://doaj.org/article/c55b2e94972b4e5e81d771671e6768dd
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/23527cc34e83488c8a953e8e4d64a094
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
HIV-associated distal sensory polyneuropathy (HIV-DSP) affects about one third of people with HIV and is characterized by distal degeneration of axons. The pathogenesis of HIV-DSP is not known and there is currently no FDA-approved treatment. HIV tra
Externí odkaz:
https://doaj.org/article/250f64692be744eea19101f3ebf3bd1b
Publikováno v:
Brain Sciences, Vol 12, Iss 3, p 308 (2022)
Therapeutic interventions are greatly needed for age-related neurodegenerative diseases. Astrocytes regulate many aspects of neuronal function including bioenergetics and synaptic transmission. Reactive astrocytes are implicated in neurodegenerative
Externí odkaz:
https://doaj.org/article/e53654dabb6544cea7d9988f6032e70e
Autor:
Changyoun Kim, Brian Spencer, Edward Rockenstein, Hodaka Yamakado, Michael Mante, Anthony Adame, Jerel Adam Fields, Deborah Masliah, Michiyo Iba, He-Jin Lee, Robert A. Rissman, Seung-Jae Lee, Eliezer Masliah
Publikováno v:
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-18 (2018)
Abstract Background Synucleinopathies of the aging population are an heterogeneous group of neurological disorders that includes Parkinson’s disease (PD) and dementia with Lewy bodies (DLB) and are characterized by the progressive accumulation of
Externí odkaz:
https://doaj.org/article/dadb293950f74e659342843756240f2d
Autor:
Mary K. Swinton, Erin E. Sundermann, Lauren Pedersen, Jacques D. Nguyen, David J. Grelotti, Michael A. Taffe, Jennifer E. Iudicello, Jerel Adam Fields
Publikováno v:
Viruses, Vol 13, Iss 9, p 1742 (2021)
HIV-associated neurocognitive disorders (HAND) persist despite the advent of antiretroviral therapy (ART), suggesting underlying systemic and central nervous system (CNS) inflammatory mechanisms. The endogenous cannabinoid receptors 1 and 2 (CB1 and
Externí odkaz:
https://doaj.org/article/adfb2710ac0648b692b7360140d470f1