Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Jerel A. Fields"'
Autor:
Ronald J. Ellis, Monica Diaz, Ned Sacktor, Christina Marra, Ann C. Collier, David B. Clifford, Nigel Calcutt, Jerel A. Fields, Robert K. Heaton, Scott L. Letendre, for the CNS Antiretroviral Therapy Effects Research (CHARTER) Study Group
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 7, Pp 1166-1173 (2020)
Abstract Objective Distal sensory polyneuropathy (DSP) and neuropathic pain are important clinical concerns in virally suppressed people with HIV. We determined how these conditions evolved, what factors influenced their evolution, and their clinical
Externí odkaz:
https://doaj.org/article/9cb1cb04db55467e948211f52ff738fd
Autor:
Ali Boustani, Jacqueline R. Kulbe, Mohammadsobhan Sheikh Andalibi, Josué Pérez-Santiago, Sanjay R. Mehta, Ronald J. Ellis, Jerel Adam Fields
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4732 (2024)
Distal sensory polyneuropathy (DSP) and distal neuropathic pain (DNP) remain significant challenges for older people with HIV (PWH), necessitating enhanced clinical attention. HIV and certain antiretroviral therapies (ARTs) can compromise mitochondri
Externí odkaz:
https://doaj.org/article/629f8b7dfe1e403685a18a7315a31d22
Autor:
Mohammadsobhan Sheikh Andalibi, Jerel Adam Fields, Jennifer E. Iudicello, Monica M. Diaz, Bin Tang, Scott L. Letendre, Ronald J. Ellis
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 8, p 4245 (2024)
Distal sensory polyneuropathy (DSP) is a disabling, chronic condition in people with HIV (PWH), even those with viral suppression of antiretroviral therapy (ART), and with a wide range of complications, such as reduced quality of life. Previous studi
Externí odkaz:
https://doaj.org/article/39eea6e0a8814efc82e1043987a7a71e
Autor:
Jerel Adam Fields, Mary Swinton, Erin E. Sundermann, Nicholas Scrivens, Kaylie-Anna Juliette Vallee, David J. Moore
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
People with HIV (PWH) continue to suffer from dysfunction of the central nervous system, as evidenced by HIV-associated neurocognitive disorder (HAND), despite antiretroviral therapy and suppressed viral loads. As PWH live longer they may also be at
Externí odkaz:
https://doaj.org/article/4afb9e818e594363b6a4c7323f53ff43
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-16 (2020)
Abstract Background HIV-associated neurocognitive disorders (HAND) persist in the era of combined antiretroviral therapy (ART) despite reductions in viral load (VL) and overall disease severity. The mechanisms underlying HAND in the ART era are not w
Externí odkaz:
https://doaj.org/article/c55b2e94972b4e5e81d771671e6768dd
Publikováno v:
Brain Sciences, Vol 12, Iss 3, p 308 (2022)
Therapeutic interventions are greatly needed for age-related neurodegenerative diseases. Astrocytes regulate many aspects of neuronal function including bioenergetics and synaptic transmission. Reactive astrocytes are implicated in neurodegenerative
Externí odkaz:
https://doaj.org/article/e53654dabb6544cea7d9988f6032e70e
Autor:
Changyoun Kim, Brian Spencer, Edward Rockenstein, Hodaka Yamakado, Michael Mante, Anthony Adame, Jerel Adam Fields, Deborah Masliah, Michiyo Iba, He-Jin Lee, Robert A. Rissman, Seung-Jae Lee, Eliezer Masliah
Publikováno v:
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-18 (2018)
Abstract Background Synucleinopathies of the aging population are an heterogeneous group of neurological disorders that includes Parkinson’s disease (PD) and dementia with Lewy bodies (DLB) and are characterized by the progressive accumulation of
Externí odkaz:
https://doaj.org/article/dadb293950f74e659342843756240f2d
Autor:
Eugenia Ricciardelli, Francesca Telese, Patricia Montilla-Perez, Jerel Adam Fields, Mary K Swinton
Publikováno v:
Cannabis and cannabinoid research, vol 7, iss 1
Cannabis Cannabinoid Res
Cannabis Cannabinoid Res
Background: Alterations of astrocyte function play a crucial role in neuroinflammatory diseases due to either the loss of their neuroprotective role or the gain of their toxic inflammatory properties. Accumulating evidence highlights that cannabinoid
Autor:
Jacqueline Kulbe, Mary Swinton, Anh Le, Anna Laird, Nicholas Scrivens, Michael Mante, Jazmin Florio, Robert Rissman, Jerel Adam Fields
Publikováno v:
Biological Psychiatry. 93:S186-S187
Autor:
Eliezer Masliah, Michael Mante, Anthony Adame, Brian Spencer, Seung-Jae Lee, Edward Rockenstein, Jerel A. Fields, Soo Jean Shin, Somin Kwon, Robert A. Rissman, Michiyo Iba, Changyoun Kim
Publikováno v:
Experimental & Molecular Medicine
Synucleinopathies are age-related neurological disorders characterized by the progressive deposition of α-synuclein (α-syn) aggregates and include Parkinson’s disease (PD) and dementia with Lewy bodies (DLB). Although cell-to-cell α-syn transmis