Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jerca Pahor"'
Publikováno v:
Synthesis. 48:3763-3772
Seven new masked analogues of phosphopantothenate, suitable for an evaluation of their potential ability to restore intracellular coenzyme A (CoA) levels, were successfully synthesized in good to moderate yields. The preparation of derivatives masked
Autor:
Emanuela Rizzetto, Marianne de Villiers, Alen Čusak, Marianne van der Zwaag, Jerca Pahor, Susan J. Hayflick, Balaji Srinivasan, Ody C. M. Sibon, Jeffrey Hamada, Nicola A. Grzeschik, Gregor Kosec, Cristina Colombelli, Valeria Tiranti, Pieter G. Tepper, Suh Young Jeong, Clara H Harrs, Randall L. Woltjer, Liza L. Lahaye, Rachel Fox, Theo de Boer, Ivano Di Meo, Branko Jenko
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports, 7(1):11260. Nature Publishing Group
Scientific Reports
Scientific Reports, 7(1):11260. Nature Publishing Group
Scientific Reports
Coenzyme A is an essential metabolite known for its central role in over one hundred cellular metabolic reactions. In cells, Coenzyme A is synthesized de novo in five enzymatic steps with vitamin B5 as the starting metabolite, phosphorylated by panto
Autor:
Branko Jenko, Gregor Kosec, Hrvoje Petkovic, Ajda Podgorsek Berke, Jerca Pahor, Alen Čusak, Ody Sibon, Balaji Srinivasan
Publikováno v:
University of Groningen
The invention relates to (S)-acyl-4'-phosphopantetheine derivatives, methods of their synthesis, and related medical uses of such compounds. Preferred medical uses relate to the treatment of neurodegenerative diseases, such as PKAN.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5f0687a87c4955a8498f38c5ba10c034
https://research.rug.nl/en/publications/61bfd703-1c15-4a78-bb65-01ecb3e4601f
https://research.rug.nl/en/publications/61bfd703-1c15-4a78-bb65-01ecb3e4601f