Zobrazeno 1 - 10 of 18 pro vyhledávání: '"Jeran K Stratford"'
1
Akademický článek
Genetic and pharmacological inhibition of TTK impairs pancreatic cancer cell line growth by inducing lethal chromosomal instability.
Autor: Jeran K Stratford, Feng Yan, Rebecca A Hill, Michael B Major, Lee M Graves, Channing J Der, Jen Jen Yeh
Publikováno v: PLoS ONE, Vol 12, Iss 4, p e0174863 (2017)
Pancreatic ductal adenocarcinoma, which accounts for the majority of pancreatic cancers, is a lethal disease with few therapeutic options. Genomic profiling of pancreatic ductal adenocarcinoma has identified a complex and heterogeneous landscape. Und
Externí odkaz: https://doaj.org/article/a4307da2b3164585b704755c21db35c6
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2
Akademický článek
Differential gene expression between African American and European American colorectal cancer patients.
Autor: Biljana Jovov, Felix Araujo-Perez, Carlie S Sigel, Jeran K Stratford, Amber N McCoy, Jen Jen Yeh, Temitope Keku
Publikováno v: PLoS ONE, Vol 7, Iss 1, p e30168 (2012)
The incidence and mortality of colorectal cancer (CRC) is higher in African Americans (AAs) than other ethnic groups in the U. S., but reasons for the disparities are unknown. We performed gene expression profiling of sporadic CRCs from AAs vs. Europ
Externí odkaz: https://doaj.org/article/20a8c1a0632241e18c13baf27136bdc0
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3
Akademický článek
A six-gene signature predicts survival of patients with localized pancreatic ductal adenocarcinoma.
Autor: Jeran K Stratford, David J Bentrem, Judy M Anderson, Cheng Fan, Keith A Volmar, J S Marron, Elizabeth D Routh, Laura S Caskey, Jonathan C Samuel, Channing J Der, Leigh B Thorne, Benjamin F Calvo, Hong Jin Kim, Mark S Talamonti, Christine A Iacobuzio-Donahue, Michael A Hollingsworth, Charles M Perou, Jen Jen Yeh
Publikováno v: PLoS Medicine, Vol 7, Iss 7, p e1000307 (2010)
Pancreatic ductal adenocarcinoma (PDAC) remains a lethal disease. For patients with localized PDAC, surgery is the best option, but with a median survival of less than 2 years and a difficult and prolonged postoperative course for most, there is an u
Externí odkaz: https://doaj.org/article/8637234746224f3e9ffbe1636aaf9a1d
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8
Abstract 394: Prognosis and molecular characteristics of patients with TRK fusion cancer in the 100,000 Genomes Project
Autor: Karen Keating, Lyudmila Bazhenova, Jihong Zong, John A. Reeves, Amanda Bruno, John Bridgewater, Xiaolong Jiao, Jeran K. Stratford, Mounika Parimi, Atanas Kamburov, Arndt Schmitz, Clare Flach, Marc Mardoche Fellous
Publikováno v: Cancer Research. 81:394-394
Background: NTRK gene fusions are oncogenic drivers in various tumor types. Overall survival (OS) of patients (pts) with tumors harboring NTRK fusions compared to pts without is unknown, and data on co-occurrence of NTRK fusions with other oncogenic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8d838ee718ae02287142c3492da28c7e
https://doi.org/10.1158/1538-7445.am2021-394
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9
CNV Radar: an improved method for somatic copy number alteration characterization in oncology
Autor: Wendell D. Jones, Angela Dispenzieri, Daniel Auclair, Faith E. Davies, Nizar J. Bahlis, Michael Schaffer, Hervé Avet-Loiseau, Jonathan J Keats, A. Kate Sasser, Jordan M. Schecter, Christopher Chiu, Chad Brown, Ming Qi, Jeran K. Stratford, David Soong, Jason G. Powers
Publikováno v: BMC Bioinformatics
BMC Bioinformatics, Vol 21, Iss 1, Pp 1-18 (2020)
Background Cancer associated copy number variation (CNV) events provide important information for identifying patient subgroups and suggesting treatment strategies. Technical and logistical issues, however, make it challenging to accurately detect ab
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc4ef559ba38c7506cbc0d1a73903fd2
https://pubmed.ncbi.nlm.nih.gov/32143562
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10
Response to MLN8237 in Pancreatic Cancer Is Not Dependent on RalA Phosphorylation
Autor: Jeffrey Ecsedy, Nicole F. Neel, Vaishali Shinde, Channing J. Der, Jeran K. Stratford, Jen Jen Yeh, Timothy D. Martin
Publikováno v: Molecular Cancer Therapeutics. 13:122-133
The high prevalence of KRAS mutations and importance of the RalGEF–Ral pathway downstream of activated K-ras in pancreatic ductal adenocarcinoma (PDAC) emphasize the importance of identifying novel methods by which to therapeutically target these p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25e9fb6c27ec2f67a34b1f19caf4f303
https://doi.org/10.1158/1535-7163.mct-12-1232
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