Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jerald Schindler"'
Publikováno v:
Pharmaceutical Statistics. 14:172-179
A late-stage clinical development program typically contains multiple trials. Conventionally, the program's success or failure may not be known until the completion of all trials. Nowadays, interim analyses are often used to allow evaluation for earl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a27195d8074f7f8e18ad636502c2c4fc
https://doi.org/10.1002/pst.1670
https://doi.org/10.1002/pst.1670
Autor:
Weili He, Keaven M. Anderson, James A. Bolognese, Lina Li, Nicole Dossin, Jerald Schindler, Mark Harmer, Yevgen Tymofyeyev, Cathy Leahy, Olga M. Kuznetsova
Publikováno v:
Drug Information Journal. 46:160-174
There is great potential for clinical trials designed with adaptive features to result in more efficient decision making within a drug development program. However, clinical trials with adaptive features are more complex to implement than traditional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::301d20139d34ab8dfbee2958135efe6d
https://doi.org/10.1177/0092861512436580
https://doi.org/10.1177/0092861512436580
Publikováno v:
Pharmaceutical statistics. 14(3)
A late-stage clinical development program typically contains multiple trials. Conventionally, the program's success or failure may not be known until the completion of all trials. Nowadays, interim analyses are often used to allow evaluation for earl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3a50c925a41d25341953733ace883e95
https://pubmed.ncbi.nlm.nih.gov/25645143
https://pubmed.ncbi.nlm.nih.gov/25645143
Autor:
Marc A. Pfeffer, Lu Tian, Jerald Schindler, Lee-Jen Wei, Scott D. Solomon, Hajime Uno, Lihui Zhao
Background Consider a comparative, randomized clinical study with a specific event time as the primary end point. In the presence of censoring, standard methods of summarizing the treatment difference are based on Kaplan–Meier curves, the logrank t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d58bb0f5a1f79c3fdb9862d5d3490e0
https://europepmc.org/articles/PMC3705645/
https://europepmc.org/articles/PMC3705645/
Autor:
Gallo, Paul1 (AUTHOR) paul.gallo@novartis.com, Chuang-Stein, Christy2 (AUTHOR), Dragalin, Vladimir3 (AUTHOR), Gaydos, Brenda4 (AUTHOR), Krams, Michael5 (AUTHOR), Pinheiro, José1 (AUTHOR)
Publikováno v:
Journal of Biopharmaceutical Statistics. Jun2006, Vol. 16 Issue 3, p275-283. 9p.
Publikováno v:
Pharmaceutical Statistics; May2015, Vol. 14 Issue 3, p172-179, 8p