Zobrazeno 1 - 10
of 509
pro vyhledávání: '"Jerald P, Radich"'
Autor:
Jasmine Naru, Megan Othus, ChenWei Lin, Melinda A. Biernacki, Marie Bleakley, Thomas R. Chauncey, Harry P. Erba, Min Fang, Matthew P. Fitzgibbon, Phillip R. Gafken, Richard G. Ivey, Jacob J. Kennedy, Travis D. Lorentzen, Soheil Meshinchi, Anna Moseley, Era L. Pogosova‐Agadjanyan, Vivian M. Liu, Jerald P. Radich, Uliana J. Voytovich, Pei Wang, Jeffrey R. Whiteaker, Cheryl L. Willman, Feinan Wu, Amanda G. Paulovich, Derek L. Stirewalt
Publikováno v:
eJHaem, Vol 5, Iss 6, Pp 1243-1251 (2024)
Abstract Introduction Acute myeloid leukemia (AML) remains one of the deadliest hematopoietic malignancies. A better understanding of the molecular biology governing AML may lead to improved risk stratification and facilitate the development of novel
Externí odkaz:
https://doaj.org/article/18d3b04e042e48a2a897b435a871a0b6
Autor:
Jayastu Senapati, Koji Sasaki, Ghayas C. Issa, Jeffrey H. Lipton, Jerald P. Radich, Elias Jabbour, Hagop M. Kantarjian
Publikováno v:
Blood Cancer Journal, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract With the improving knowledge of CML and its management, the goals of therapy need to be revisited to ensure an optimal use of the BCR::ABL1 TKIs in the frontline and later-line therapy of CML. In the frontline therapy of CML in the chronic p
Externí odkaz:
https://doaj.org/article/f3199252ca5c405e9dd66942feadd154
Autor:
Era L. Pogosova-Agadjanyan, Xing Hua, Megan Othus, Frederick R. Appelbaum, Thomas R. Chauncey, Harry P. Erba, Matthew P. Fitzgibbon, Isaac C. Jenkins, Min Fang, Stanley C. Lee, Anna Moseley, Jasmine Naru, Jerald P. Radich, Jenny L. Smith, Brooke E. Willborg, Cheryl L. Willman, Feinan Wu, Soheil Meshinchi, Derek L. Stirewalt
Publikováno v:
Biomarker Research, Vol 11, Iss 1, Pp 1-12 (2023)
Abstract Background Studies have not systematically compared the ability to verify performance of prognostic transcripts in paired bulk mononuclear cells versus viable CD34-expressing leukemic blasts from patients with acute myeloid leukemia. We hypo
Externí odkaz:
https://doaj.org/article/068af1ff03784be8bc61228665d49697
Autor:
Laura W. Dillon, Jake Higgins, Hassan Nasif, Megan Othus, Lan Beppu, Thomas H. Smith, Elizabeth Schmidt, Charles C. Valentine III, Jesse J. Salk, Brent L Wood, Harry P. Erba, Jerald P. Radich, Christopher S. Hourigan
Publikováno v:
Haematologica, Vol 109, Iss 2 (2023)
The presence of measurable residual disease (MRD) is strongly associated with treatment outcomes in acute myeloid leukemia (AML). Despite the correlation with clinical outcomes, MRD assessment has yet to be standardized or routinely incorporated into
Externí odkaz:
https://doaj.org/article/5ddca69089a4412bafc0c569c3e4ed97
Autor:
Christina M. Termini, Anna Moseley, Megan Othus, Frederick R. Appelbaum, Thomas R. Chauncey, Harry P. Erba, Min Fang, Stanley C. Lee, Jasmine Naru, Era L. Pogosova-Agadjanyan, Jerald P. Radich, Cheryl L. Willman, Feinan Wu, Soheil Meshinchi, Derek L. Stirewalt
Publikováno v:
Haematologica, Vol 108, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/4c2f1cc13a4d4e82997fde8282f05c18
Autor:
Deepti Reddi, Brandon W. Seaton, David Woolston, Lauri Aicher, Luke D. Monroe, Zhengwei J. Mao, Jill C. Harrell, Jerald P. Radich, Anjali Advani, Nikolaos Papadantonakis, Cecilia C. S. Yeung
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract To investigate aldo–keto reductase 1C3 (AKR1C3) expression in T and B acute lymphoblastic leukemia/lymphoma (ALL) patients. Three commercial antibodies were evaluated for AKR1C3 immunohistochemistry (IHC) staining performance: Polyclonal T
Externí odkaz:
https://doaj.org/article/d9f0d764d2d24b37b37880b7ec019bff
Autor:
Jerald P. Radich, Matthew Wall, Susan Branford, Catarina D. Campbell, Shalini Chaturvedi, Daniel J. DeAngelo, Michael Deininger, Justin Guinney, Andreas Hochhaus, Timothy P Hughes, Hagop M. Kantarjian, Richard A. Larson, Sai Li, Rodrigo Maegawa, Kaushal Mishra, Vanessa Obourn, Javier Pinilla-Ibarz, Das Purkayastha, Islam Sadek, Giuseppe Saglio, Alok Shrestha, Brian S. White, Brian J. Druker
Publikováno v:
Haematologica, Vol 108, Iss 6 (2023)
Tyrosine kinase inhibitor therapy revolutionized chronic myeloid leukemia treatment and showed how targeted therapy and molecular monitoring could be used to substantially improve survival outcomes. We used chronic myeloid leukemia as a model to unde
Externí odkaz:
https://doaj.org/article/0ea048e8ba4f46a6a15bd5a4b185ec55
Autor:
Shishir Reddy, Ling-Hong Hung, Olga Sala-Torra, Jerald P. Radich, Cecilia CS Yeung, Ka Yee Yeung
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-8 (2021)
Abstract Background Long-read sequencing has great promise in enabling portable, rapid molecular-assisted cancer diagnoses. A key challenge in democratizing long-read sequencing technology in the biomedical and clinical community is the lack of graph
Externí odkaz:
https://doaj.org/article/ff2c02551adb4007b0a074feaace793b
Autor:
Seth Rowley, Pat Garcia-Gonzalez, Jerald P. Radich, Ann Kim Novakowski, Irina Usherenko, Joseph B. Babigumira
Publikováno v:
Cost Effectiveness and Resource Allocation, Vol 19, Iss 1, Pp 1-8 (2021)
Abstract Purpose To estimate the resource gap in the polymerase chain reaction (PCR) monitoring for patients with chronic myeloid leukemia (CML) in low- and middle-income countries (LMICs). Methods We developed a model of demand and supply of PCR mon
Externí odkaz:
https://doaj.org/article/9a67a2fcc9e14ad592b545c83ce441b8
Autor:
Kathryn E. Flynn, Ehab Atallah, Li Lin, Neil P. Shah, Richard T. Silver, Richard A. Larson, Javier Panilla-Ibarz, James E. Thompson, Vivian G. Oehler, Jerald P. Radich, Vamsi Kota, Michael J. Mauro, Charles A. Schiffer, Jorge Cortes, Kevin P. Weinfurt
Publikováno v:
Haematologica, Vol 107, Iss 11 (2022)
For patients with optimally treated chronic myeloid leukemia (CML), discontinuation of tyrosine kinase inhibitor (TKI) therapy can lead to treatment-free remission. In previous trials, TKI discontinuation has been associated with increased musculoske
Externí odkaz:
https://doaj.org/article/fde5fc50709645bd8d4231a3125fa50f