Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Jerald J. Bernstein"'
Publikováno v:
Neuroscience Letters. 322:62-66
Cells cultured from Alzheimer disease leptomeninges or skin were grafted into the cortex of adult thymectomized rats. At 3 days post-implant, plaque-like aggregates were found in the cortex, corpus callosum, septum and caudate nucleus. These structur
Autor:
Giles H. Vince, Karl H. Plate, Joerg-Christian Tonn, Roland Goldbrunner, Klaus Roosen, Jerald J. Bernstein
Publikováno v:
Journal of Neuroscience Research. 55:486-495
Aim of this study was to develop and characterize an applicable in vivo model to investigate angiogenesis of human gliomas. An established glioblastoma spheroid model was used to investigate the neovascularization of a standardized avascular solid tu
Publikováno v:
Microscopy Research and Technique. 43:250-257
Cell adhesion receptors of the integrin superfamily, CD44, and adhesion receptors of the immunoglobulin superfamily are expressed by high-grade astrocytic tumors of the central nervous system. These receptors are critical for the invasion of these tu
Publikováno v:
International Journal of Developmental Neuroscience. 14:681-687
The following series of experiments explores the post-xenografting differentiation of a naturally occurring, non-neuronal cell cultured from the leptomeninges of an 84-year-old woman. In culture, flat process-bearing human cells from the leptomeninge
Autor:
Jerald J. Bernstein, Sean M. Karp
Publikováno v:
International Journal of Developmental Neuroscience. 14:177-180
Astrocytes appear to be excluded from blood vessels. In order to test this observation, pial blood vessels were seeded upon cultures of purified E14 fetal astrocytes. One to seven days later co-cultures were immunohistochemically stained for laminin
Autor:
Jerald J. Bernstein, W J Goldberg
Publikováno v:
Spinal Cord. 33:250-253
Publikováno v:
Neurosurgery. 36:124-132
Glioblastoma is very rarely found outside the central nervous system. The ability of rat C6 glioblastoma cells to intravasate into central nervous system and pial blood vessels is tested using a rat homografting model and two in vitro models. In vivo
Autor:
William J. Goldberg, Gauri Tadvalkar, Lawrence R. Wood, Kirstiaan V. Levine, Edward R. Laws, Jerald J. Bernstein
Publikováno v:
Neurosurgery. 28:652-658
Cortically homografted C6 glioma-astrocytoma cells both invade the rat host brain as a mass and migrate as individual cells. In contrast, fetal astrocytes derived from homografted whole pieces of fetal cortex migrate only as individual cells througho
Publikováno v:
International Journal of Developmental Neuroscience. 9:427-433
Cultured C6 glioma cells were prelabeled with the plant lectin Phaseolus vulgaris leuco-agglutinin (PHAL) and grafted as a cell suspension (10(6) cells in 5.0 microliters) into freshly made cortical implantation pockets in adult host rats. Animals we
Publikováno v:
Restorative Neurology and Neuroscience. 2:261-270
In a 'double blind' study, 2 series of adult rats were trained to traverse a narrow bar or a horizontal ladder for a water reward. Hindlimb placement (measured as hindlimb foot slips) of the subjects trained on the narrow platform was ranked. The sub