Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jer Jang Chang"'
Autor:
Kuo Hsuing Lee, De Cheng Zhang, Hsien Chang Chang, Chang Ming Cheng, Jer Jang Chang, Hsien Tsung Chen, Yoshiki Kashiwada, Yuh Pan Chen
Publikováno v:
Journal of Natural Products. 56:2077-2082
Three new p-coumaroyl triterpenes, asprellic acids A [1], B [2], and C [3], were isolated from the EtOH extract of dried leaves of Ilex asprella. The structures for 1-3 have been established as 3,27-di-O-trans-p-coumaroyl [1], 3-O-trans-p-coumaroyl-2
Autor:
K.‐H. Lee, Toshihiro Fujioka, Yoshiki Kashiwada, Kunihide Mihashi, Ih Sheng Chen, Jer Jang Chang
Publikováno v:
ChemInform. 24
Publikováno v:
ChemInform. 25
6-Amino-2-mercapto-5-methylpyrimidine-4-carboxylic acid (AMMPCA) was found to be a potent hypolipidemic agent at oral closes of 10 and 20 mg/kg/day in rodents. This agent was observed to affect de novo lipid synthesizing enzyme activities in a manner
Autor:
Kunihide Mihashi, Jer Jang Chang, Ih-Sheng Chen, Yoshiki Kashiwada, Toshihiro Fujioka, Kuo Hsiung Lee
Publikováno v:
The Journal of Organic Chemistry. 57:6946-6953
Six new triterpene glucosides, cumingianosides A-F (1-6) as well as trisnor- and a tetranortriterpene glucoside, cumindysosides A (7) and B (8), wiht a 14,18-cycloapoeuphane-type skeleton have been isolated from Dysoxylum cumingianum as antileukemic
Publikováno v:
Journal of Natural Products. 55:1033-1043
Fifty-seven tannins and related compounds, including gallotannins, ellagitannins, and condensed and complex tannins, were evaluated for their cytotoxicities against human tumor cell lines, including malignant melanoma, lung carcinoma, ileocecal adeno
Autor:
Hui Kang Wang, Kou Maou Hwang, Su Ying Liu, Jer Jang Chang, Kuo Hsiung Lee, Jing Xi Xie, Lawrence M. Ballas, Jack B. Jiang
Publikováno v:
Journal of Medicinal Chemistry. 35:2717-2721
Shiraiachrome-A and -B have been isolated from the mycelium of the Chinese bamboo fungus Shiraia bambusicola as the cytotoxic principles. A series of new perylene derivatives (7-27) related to Shiraiachrome-A and -B as well as Calphostin-C have been
Autor:
Kunihide Mihashi, Jer Jang Chang, Ih-Sheng Chen, Yoshiki Kashiwada, Toshihiro Fujioka, Kuo Hsiung Lee
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 2:395-398
Cumindysoside A, a novel trisnortriterpene glucoside with a 14, 18-cycloapoeuphane-type skeleton, has been isolated from Dysoxylum cumingianum as a cytotoxic principle. Its structure was established from spectroscopic evidence.
The Cytotoxic Principles ofPseudolarix kaempferi: Pseudolaric Acid-A and -B and Related Derivatives1
Publikováno v:
Planta Medica. 56:383-385
Pseudolaric acid-A and -B, the novel diterpene acids isolated from Pseudolarix kaempferi, and their related derivatives have been tested for cytotoxicity against KB, A-549, HCT-8, P-388, and L-1210 tumor cells. The results showed that pseudolaric aci
Autor:
Chii M. Lin, Ernest Hamel, Hong Zin Lee, Jer Jang Chang, Dan Lednicer, Kuo Hsiung Lee, Tian Shung Wu, Yih Tyng Lin, Jung Pin Juang, Sheng-Chu Kuo, Kenneth D. Paull
Publikováno v:
Journal of medicinal chemistry. 36(9)
A series of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds have been synthesized and evaluated as cytotoxic compounds and as antimitotic agents interacting with tubulin. The 2-phenyl-4-quinolones (22-30) with substit
Autor:
Jer Jang Chang, Ernest Hamel, Andrew T. McPhail, Chii M. Lin, Li Sun, Susan Bane Hastie, Kuo Hsiung Lee
Publikováno v:
Journal of medicinal chemistry. 36(5)
A series of novel thiocolchicine analogs, 5,6-dihydro-6(S)-(acyloxy)-and 5,6-dihydro-6(S)-[(aroyloxy)-methyl]-1,2,3-trimethoxy-9-(methylthi o)-8H- cyclohepta[a]naphthalen-8-ones, possessing a six-membered ring B, have been synthesized and evaluated f