Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jerôme Gilleron"'
Autor:
Serena Petracchini, Daniel Hamaoui, Anne Doye, Atef Asnacios, Florian Fage, Elisa Vitiello, Martial Balland, Sebastien Janel, Frank Lafont, Mukund Gupta, Benoit Ladoux, Jerôme Gilleron, Teresa M. Maia, Francis Impens, Laurent Gagnoux-Palacios, Mads Daugaard, Poul H. Sorensen, Emmanuel Lemichez, Amel Mettouchi
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)
Uropathogenic strains of Escherichia coli (UPEC) are a leading cause of urinary tract infections (UTIs) and invasion involves Rho GTPase members, notably Rac1, to drive actin cytoskeleton rearrangement leading to engulfment. Here, Petracchini et al.
Externí odkaz:
https://doaj.org/article/1958110237ff42f391f49c167f39e785
Autor:
Alexandre Gallerand, Bastien Dolfi, Marion I. Stunault, Zakariya Caillot, Alexia Castiglione, Axelle Strazzulla, Chuqiao Chen, Gyu Seong Heo, Hannah Luehmann, Flora Batoul, Nathalie Vaillant, Adélie Dumont, Thomas Pilot, Johanna Merlin, Fairouz N. Zair, Jerome Gilleron, Adeline Bertola, Peter Carmeliet, Jesse W. Williams, Rafael J. Arguello, David Masson, David Dombrowicz, Laurent Yvan-Charvet, Denis Doyen, Arvand Haschemi, Yongjian Liu, Rodolphe R. Guinamard, Stoyan Ivanov
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Monocytes directly contribute to atherosclerosis development by their recruitment to plaques in which they differentiate into macrophages. In the present study, we ask how modulating monocyte glucose metabolism could affect their homeostasis
Externí odkaz:
https://doaj.org/article/75ff188150004c8a83111624efceb8a1
Autor:
Marina Blanc, Lama Habbouche, Peng Xiao, Cynthia Lebeaupin, Marion Janona, Nathalie Vaillant, Marie Irondelle, Jérôme Gilleron, Florent Murcy, Déborah Rousseau, Carmelo Luci, Thibault Barouillet, Sandrine Marchetti, Sandra Lacas-Gervais, Laurent Yvan-Charvet, Philippe Gual, Alessandra K. Cardozo, Béatrice Bailly-Maitre
Publikováno v:
Cell Death and Disease, Vol 15, Iss 5, Pp 1-13 (2024)
Abstract The prevalence of diabetes steadily increases worldwide mirroring the prevalence of obesity. Endoplasmic reticulum (ER) stress is activated in diabetes and contributes to β-cell dysfunction and apoptosis through the activation of a terminal
Externí odkaz:
https://doaj.org/article/04bf8949dea34eb980f757a66bea4105
Autor:
Jérôme Gilleron, Abderrahman Chafik, Sandra Lacas-Gervais, Jean-François Tanti, Mireille Cormont
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-21 (2024)
Abstract Background The trafficking of cargoes from endosomes to the trans-Golgi network requires numerous sequential and coordinated steps. Cargoes are sorted into endosomal-derived carriers that are transported, tethered, and fused to the trans-Gol
Externí odkaz:
https://doaj.org/article/5ad83691a217409291345c0fa586ceec
Autor:
Alexandre Gallerand, Marion I. Stunault, Johanna Merlin, Hannah P. Luehmann, Deborah H. Sultan, Maria M. Firulyova, Virginie Magnone, Narges Khedher, Antoine Jalil, Bastien Dolfi, Alexia Castiglione, Adelie Dumont, Marion Ayrault, Nathalie Vaillant, Jérôme Gilleron, Pascal Barbry, David Dombrowicz, Matthias Mack, David Masson, Thomas Bertero, Burkhard Becher, Jesse W. Williams, Konstantin Zaitsev, Yongjian Liu, Rodolphe R. Guinamard, Laurent Yvan-Charvet, Stoyan Ivanov
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Adipose tissue is composed of a number of adipocytes and a number of other cells including immune cells. Here the authors use single-cell sequencing of murine brown adipose tissue immune cells and describe multiple macrophage and monocyte subsets and
Externí odkaz:
https://doaj.org/article/e27f3045057046fd93f4d2ad42eab91a
Autor:
Bastien Dolfi, Alexandre Gallerand, Maria M. Firulyova, Yingzheng Xu, Johanna Merlin, Adélie Dumont, Alexia Castiglione, Nathalie Vaillant, Sandrine Quemener, Heidi Gerke, Marion I. Stunault, Patricia R. Schrank, Seung-Hyeon Kim, Alisha Zhu, Jie Ding, Jerome Gilleron, Virginie Magnone, Pascal Barbry, David Dombrowicz, Christophe Duranton, Abdelilah Wakkach, Claudine Blin-Wakkach, Burkhard Becher, Sophie Pagnotta, Rafael J. Argüello, Pia Rantakari, Svetoslav Chakarov, Florent Ginhoux, Konstantin Zaitsev, Ki-Wook Kim, Laurent Yvan-Charvet, Rodolphe R. Guinamard, Jesse W. Williams, Stoyan Ivanov
Publikováno v:
Cell Reports, Vol 39, Iss 11, Pp 110949- (2022)
Summary: Despite the ubiquitous function of macrophages across the body, the diversity, origin, and function of adrenal gland macrophages remain largely unknown. We define the heterogeneity of adrenal gland immune cells using single-cell RNA sequenci
Externí odkaz:
https://doaj.org/article/845024ae304b4b1f9ea363f1e31a4bbd
Autor:
Stéphanie Torrino, Victor Tiroille, Bastien Dolfi, Maeva Dufies, Charlotte Hinault, Laurent Bonesso, Sonia Dagnino, Jennifer Uhler, Marie Irondelle, Anne-sophie Gay, Lucile Fleuriot, Delphine Debayle, Sandra Lacas-Gervais, Mireille Cormont, Thomas Bertero, Frederic Bost, Jerome Gilleron, Stephan Clavel
Publikováno v:
eLife, Vol 10 (2021)
To adapt in an ever-changing environment, cells must integrate physical and chemical signals and translate them into biological meaningful information through complex signaling pathways. By combining lipidomic and proteomic approaches with functional
Externí odkaz:
https://doaj.org/article/3b8ac826e8224f39920b2d2a0010217a
Autor:
Georges Raad, Fabrizio Serra, Luc Martin, Marie-Alix Derieppe, Jérôme Gilleron, Vera L Costa, Didier F Pisani, Ez-Zoubir Amri, Michele Trabucchi, Valerie Grandjean
Publikováno v:
eLife, Vol 10 (2021)
Obesity is a growing societal scourge. Recent studies have uncovered that paternal excessive weight induced by an unbalanced diet affects the metabolic health of offspring. These reports mainly employed single-generation male exposure. However, the c
Externí odkaz:
https://doaj.org/article/a53a94fde4e94facb24dc53adb55cc91
Autor:
Camille Loubiere, Stephan Clavel, Jerome Gilleron, Rania Harisseh, Jeremy Fauconnier, Issam Ben-Sahra, Lisa Kaminski, Kathiane Laurent, Stephanie Herkenne, Sandra Lacas-Gervais, Damien Ambrosetti, Damien Alcor, Stephane Rocchi, Mireille Cormont, Jean-François Michiels, Bernard Mari, Nathalie M. Mazure, Luca Scorrano, Alain Lacampagne, Abdallah Gharib, Jean-François Tanti, Frederic Bost
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Mitochondrial integrity is critical for the regulation of cellular energy and apoptosis. Metformin is an energy disruptor targeting complex I of the respiratory chain. We demonstrate that metformin induces endoplasmic reticulum (ER) stress,
Externí odkaz:
https://doaj.org/article/3c81dba573894f44b340dafd88a5e78b
Autor:
Simon Nicolas, Vincent Blasco‐Baque, Audren Fournel, Jerome Gilleron, Pascale Klopp, Aurelie Waget, Franck Ceppo, Alysson Marlin, Roshan Padmanabhan, Jason S Iacovoni, François Tercé, Patrice D Cani, Jean‐François Tanti, Remy Burcelin, Claude Knauf, Mireille Cormont, Matteo Serino
Publikováno v:
Molecular Systems Biology, Vol 13, Iss 3, Pp 1-17 (2017)
Abstract Gut microbiota dysbiosis has been implicated in a variety of systemic disorders, notably metabolic diseases including obesity and impaired liver function, but the underlying mechanisms are uncertain. To investigate this question, we transfer
Externí odkaz:
https://doaj.org/article/b955560a33e845d1b23e5d096d6e2b27