Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Jerónimo Jurado‐Arjona"'
Extensive transcriptional and chromatin changes underlie astrocyte maturation in vivo and in culture
Autor:
Michael Lattke, Robert Goldstone, James K. Ellis, Stefan Boeing, Jerónimo Jurado-Arjona, Nicolás Marichal, James I. MacRae, Benedikt Berninger, Francois Guillemot
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Astrocytes have functions crucial for brain homeostasis, which are disrupted in many neurological disorders, but how these functions are established during astrocyte maturation is largely unknown. Here the authors show transcriptional and chromatin c
Externí odkaz:
https://doaj.org/article/798f138617cc451ba7602ca0f438bd2d
Autor:
Julia Pose-Utrilla, Lucía García-Guerra, Ana Del Puerto, Abraham Martín, Jerónimo Jurado-Arjona, Noelia S. De León-Reyes, Andrea Gamir-Morralla, Álvaro Sebastián-Serrano, Mónica García-Gallo, Leonor Kremer, Jens Fielitz, Christofer Ireson, Mª José Pérez-Álvarez, Isidro Ferrer, Félix Hernández, Jesús Ávila, Marina Lasa, Miguel R. Campanero, Teresa Iglesias
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
Excitotoxicity due to excessive glutamate release causes oxidative stress and neuronal death, and is a feature of many brain diseases. Here the authors show that protein kinase D1 is inactivated by excitotoxicity in a model of stroke and that its act
Externí odkaz:
https://doaj.org/article/cb128c406cd844578138ccf113906e62
Autor:
Marta Bolós, María Llorens-Martín, Juan Ramón Perea, Jerónimo Jurado-Arjona, Alberto Rábano, Félix Hernández, Jesús Avila
Publikováno v:
Molecular Neurodegeneration, Vol 12, Iss 1, Pp 1-14 (2017)
Abstract Background Extracellular Tau is toxic for neighboring cells, and it contributes to the progression of AD. The CX3CL1/CX3CR1 axis is an important neuron/microglia communication mechanism. Methods We studied Tau clearance by microglia both in
Externí odkaz:
https://doaj.org/article/cb2fab112be14c36a4efe1761104760f
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
In rodents, the hippocampal dentate gyrus gives rise to newly generated dentate granule cells (DGCs) throughout life. This process, named adult hippocampal neurogenesis (AHN), converges in the functional integration of mature DGCs into the trisynapti
Externí odkaz:
https://doaj.org/article/d057576ab6cc4472999713005fb69abc
Autor:
Julia Pose-Utrilla, Lucía García-Guerra, Ana Del Puerto, Abraham Martín, Jerónimo Jurado-Arjona, Noelia S. De León-Reyes, Andrea Gamir-Morralla, Álvaro Sebastián-Serrano, Mónica García-Gallo, Leonor Kremer, Jens Fielitz, Christofer Ireson, Mª José Pérez-Álvarez, Isidro Ferrer, Félix Hernández, Jesús Ávila, Marina Lasa, Miguel R. Campanero, Teresa Iglesias
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
The original version of this Article contained an error in the spelling of the author Álvaro Sebastián-Serrano, which was incorrectly given as Álvaro Sebastián Serrano. This has now been corrected in both the PDF and HTML versions of the Article.
Externí odkaz:
https://doaj.org/article/60592296656942d89b1afe3ede1df2f3
Autor:
Wenqiang Fan, Jerónimo Jurado‐Arjona, Gregorio Alanis‐Lobato, Sophie Péron, Christian Berger, Miguel A Andrade‐Navarro, Sven Falk, Benedikt Berninger
Publikováno v:
The EMBO Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::630636bad9f72ffeeafcca7258ecdd32
https://doi.org/10.15252/embj.2021110384
https://doi.org/10.15252/embj.2021110384
Autor:
Wenqiang Fan, Jerónimo Jurado-Arjona, Gregorio Alanis-Lobato, Sophie Péron, Christian Berger, Miguel A. Andrade-Navarro, Sven Falk, Benedikt Berninger
Most adult hippocampal neural stem cells (NSCs) remain quiescent with only a minor portion undergoing active proliferation and neurogenesis. The molecular mechanisms that trigger eventually the transition from quiescence to activation are still poorl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::714a9f7313870c090e1f17ede139e633
https://doi.org/10.1101/2022.01.12.475985
https://doi.org/10.1101/2022.01.12.475985
Publikováno v:
Brain Research. 1712:47-54
We have studied the consequences of in vivo GSK3β overexpression in the cerebellum using transgenic mice with conditional expression where the transactivator tTA protein expression is driven by GFAP promoter. We demonstrate an increase in GSK3β in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60b104a614275b6cbd76b01a98ab3c28
https://doi.org/10.1016/j.brainres.2019.01.040
https://doi.org/10.1016/j.brainres.2019.01.040
Extensive transcriptional and chromatin changes underlie astrocyte maturation in vivo and in culture
Autor:
François Guillemot, Nicolás Marichal, James I. MacRae, Benedikt Berninger, Stefan Boeing, Michael Lattke, James K. Ellis, Jerónimo Jurado-Arjona, Robert J. Goldstone
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Astrocytes have essential functions in brain homeostasis that are established late in differentiation, but the mechanisms underlying the functional maturation of astrocytes are not well understood. Here we identify extensive transcriptional changes t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::073737f48b50fb566ad906fb0e088406
https://pubmed.ncbi.nlm.nih.gov/34267208
https://pubmed.ncbi.nlm.nih.gov/34267208
Autor:
Marta Bolós, Juan Ramón Perea, Julia Terreros-Roncal, Jesús Avila, María Llorens-Martín, Jerónimo Jurado-Arjona, Noemí Pallas-Bazarra
Publikováno v:
Translational Psychiatry, Vol 7, Iss 12, Pp 1-16 (2017)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Translational Psychiatry
Digital.CSIC. Repositorio Institucional del CSIC
instname
Translational Psychiatry
Tau is a neuronal microtubule-associated protein with countless physiological functions. Although the detrimental effects of insoluble aggregated Tau have been widely studied, recent evidence supports the notion that soluble Tau (composed mostly of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99251d9cf5f110e684a0317578743f56
http://link.springer.com/article/10.1038/s41398-017-0013-6
http://link.springer.com/article/10.1038/s41398-017-0013-6