Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jeppe S, Holm"'
Autor:
David Hoyos, Roberta Zappasodi, Isabell Schulze, Zachary Sethna, Kelvin César de Andrade, Dean F. Bajorin, Chaitanya Bandlamudi, Margaret K. Callahan, Samuel A. Funt, Sine R. Hadrup, Jeppe S. Holm, Jonathan E. Rosenberg, Sohrab P. Shah, Ignacio Vázquez-García, Britta Weigelt, Michelle Wu, Dmitriy Zamarin, Laura F. Campitelli, Edward J. Osborne, Mark Klinger, Harlan S. Robins, Payal P. Khincha, Sharon A. Savage, Vinod P. Balachandran, Jedd D. Wolchok, Matthew D. Hellmann, Taha Merghoub, Arnold J. Levine, Marta Łuksza, Benjamin D. Greenbaum
Publikováno v:
Hoyos, D, Zappasodi, R, Schulze, I, Sethna, Z, de Andrade, K C, Bajorin, D F, Bandlamudi, C, Callahan, M K, Funt, S A, Hadrup, S R, Holm, J S, Rosenberg, J E, Shah, S P, Vázquez-García, I, Weigelt, B, Wu, M, Zamarin, D, Campitelli, L F, Osborne, E J, Klinger, M, Robins, H S, Khincha, P P, Savage, S A, Balachandran, V P, Wolchok, J D, Hellmann, M D, Merghoub, T, Levine, A J, Łuksza, M & Greenbaum, B D 2022, ' Fundamental immune–oncogenicity trade-offs define driver mutation fitness ', Nature, vol. 606, pp. 172-179 . https://doi.org/10.1038/s41586-022-04696-z
Missense driver mutations in cancer are concentrated in a few hotspots1. Various mechanisms have been proposed to explain this skew, including biased mutational processes2, phenotypic differences3–6 and immunoediting of neoantigens7,8; however, to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::788159a08120de98426bcab992e37aaa
https://doi.org/10.1038/s41586-022-04696-z
https://doi.org/10.1038/s41586-022-04696-z
Autor:
David, Hoyos, Roberta, Zappasodi, Isabell, Schulze, Zachary, Sethna, Kelvin César, de Andrade, Dean F, Bajorin, Chaitanya, Bandlamudi, Margaret K, Callahan, Samuel A, Funt, Sine R, Hadrup, Jeppe S, Holm, Jonathan E, Rosenberg, Sohrab P, Shah, Ignacio, Vázquez-García, Britta, Weigelt, Michelle, Wu, Dmitriy, Zamarin, Laura F, Campitelli, Edward J, Osborne, Mark, Klinger, Harlan S, Robins, Payal P, Khincha, Sharon A, Savage, Vinod P, Balachandran, Jedd D, Wolchok, Matthew D, Hellmann, Taha, Merghoub, Arnold J, Levine, Marta, Łuksza, Benjamin D, Greenbaum
Publikováno v:
Nature. 606(7912)
Missense driver mutations in cancer are concentrated in a few hotspots
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ee1a0a2d5947f6c1e1c6274891165a11
https://pubmed.ncbi.nlm.nih.gov/35641605
https://pubmed.ncbi.nlm.nih.gov/35641605
Autor:
David Hoyos, Roberta Zappasodi, Isabell Schulze, Zachary Sethna, Kelvin César de Andrade, Dean F. Bajorin, Chaitanya Bandlamudi, Margaret K. Callahan, Samuel A. Funt, Sine R. Hadrup, Jeppe S. Holm, Jonathan E. Rosenberg, Sohrab P. Shah, Ignacio Vázquez-García, Britta Weigelt, Michelle Wu, Dmitriy Zamarin, Laura F. Campitelli, Edward J. Osborne, Mark Klinger, Harlan S. Robins, Payal P. Khincha, Sharon A. Savage, Vinod P. Balachandran, Jedd D. Wolchok, Matthew D. Hellmann, Taha Merghoub, Arnold J. Levine, Marta Łuksza, Benjamin D. Greenbaum
Publikováno v:
Nature. 606:E5-E5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d63d3199802a7b376dfb7162949ed15a
https://doi.org/10.1038/s41586-022-04879-8
https://doi.org/10.1038/s41586-022-04879-8